Effects of inhaled eotaxin on airway function and inflammatory cell influx in sensitised and non-sensitised guinea pigs

Pre-exposure to Staphylococcal enterotoxin A exacerbates the pulmonary allergic eosinophil recruitment in rats

“…Eotaxin and IL-5 are said to act synergistically to promote eosinophil recruitment into tissues [39][40][41]. Moreover, the increased number of eosinophils in BAL fluid has been correlated with higher eotaxin levels [42].…”

Inhibitory effects of Piper betle on production of allergic mediators by bone marrow-derived mast cells and lung epithelial cells

“…Eotaxin has high potency and selectivity as a chemoattractant for eosinophils in vivo and in vitro [17]. IL-8 is a chemotactic cytokine for neutrophils (which are involved in acute inflammation and cause various allergic symptoms) and primed eosinophils [18].…”

Estudo da resposta inflamatoria pulmonar alergica em ratos expostos a enterotoxina estafilococica do tipo A (SEA)

“…Acredita-se que a eotaxina e a IL-5 agem sinergicamente no recrutamento de eosinófilos para o tecido pulmonar inflamado (Palframan et al, 1998;Smith et al, 2006;Costa et al, 2007). Além disso, Young et al(1999) mostraram que o aumento no número de eosinófilos no LBA de macacos alérgicos correlaciona-se com os altos níveis de eotaxina.…”