Effects of Nigella sativa (Kalonji) and Honey on Lipid Profile of Hyper lipidemic Smokers

Abstract

Background:Hyper lipidemia refers to the excess of lipids in the blood of patients. The present study was carried out to investigate the effect of Nigella sativa (kalonji) and honey as compared with Atorvastatin on the lipid profile of hyper lipidemia patients with habit of smoking. Methodology: Purposes, 60 patients (3 groups of 20) of 35-65 years were selected. These patients were treated with 1 g of Nigella sativa (kalonji) seed, one tablespoon of honey, and Atorvastatin 10 mg daily in the morning at fasting for a period of 30 days. Results: The results obtained showed that Nigella sativa (kalonji), honey as well as Atorvastatin lowered significantly the levels of total cholesterol (TC), low density lipoproteins (LDL) and triglycerides (TGs) after 30 days of treatment. On the other hand, all the treatments increased HDL levels significantly after 30 days treatments were non-significant on TC and LDL levels of smokers. But after 30 days of treatment, Atorvastatin was significantly more effective than honey and Nigella sativa (kalonji). Honey reduced TGs level of smokers significantly over Nigella sativa (kalonji) and Atorvastatin. Conclusion: It can be concluded that both Nigella sativa (kalonji) and honey were as effective as Atorvastatin or more effective in some cases in reducing TC, LDL and TGs of hyper lipidemic smokers significantly while HDL levels were increased significantly.

The efficacy of Nigella Sativa L extracts to reduce cardiovascular disease risk in diabetic dyslipidemia

“…The consumption of Nigella sativa L seed was a gram per day for 30 days. This treatment had decreased TC, TG, LDL, and increasing HDL [16]. It is still in accordance with those findings, Pourghassem-Gargari et al reported that the Nigella sativa L. powder treatment at dose 7.5 g/kgbw/day and the crushed Nigella sativa L. seed added with 0.5% cholesterol rabbit diet treatment given for two months each have significantly decreased LDL and increased HDL [17].…”

Traditional Herbal Medicines, Bioactive Metabolites, and Plant Products Against COVID-19: Update on Clinical Trials and Mechanism of Actions

“…Honey mixed with N. sativa has already shown remarkable potential for treating several other diseases. This gives researchers a ray of hope to use this combination in the current pandemic (Ameen et al, 2011;Bhatti et al, 2016;Moghimipour et al, 2019) Bacillus subtilis, isolated from honey, produces a very promising antiviral component known as levan (β-2,6-fructan) that functions against many pathogenic respiratory RNA viruses. By facilitating the aggregation of cells and viruses, levan amplifies the phagocytosis procedure.…”

The Effects of Nigella Sativa seed and Nigella Sativa Honeybee on Hypercholesterolemic Rats

“…Also, From table (2) can note that all treated groups decreased significantly as compared to the positive control group. Bhatti et al, (2016) showed that Nigella sativa and honey lowered significantly the levels of total cholesterol (TC), after 30 days of in hyperlipidemic smokers. Buriro and Tayyab (2007) indicated that Nigella sativa seeds in the diet has a favorable The Effects of Nigella Sativa seed and Nigella Sativa Honeybee on Hypercholesterolemic Rats ( 11 ) Egyptian Journal for Specialized Studies -N (16) Oct 2017 effect on lipid profile by lowering the total cholesterol in albino rats.…”