Effects of salts on the stability of the cationic radical of phenothiazine derivatives

Jelı́nek, Ivan; Němcová, I.; Rychlovský, Petr

doi:10.1016/0039-9140(91)80111-c

Cited by 19 publications

(16 citation statements)

References 8 publications

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“…NaClO4, LiCl, NaCl, KCl, NH4Cl, Na2SO4. 13 It was found that cationic radicals are stable in acidic media. This property was the basis for the development of a number of spectrophotometric methods for the determination of phenothiazines.…”

mentioning

confidence: 99%

Efficient Oxidizing Agents for Determination of 2,10-Disubstituted Phenothiazines

Puzanowska-Tarasiewicz

Kuźmicka

Karpińska

et al. 2005

ANAL. SCI.

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confidence: 99%

Efficient Oxidizing Agents for Determination of 2,10-Disubstituted Phenothiazines

Puzanowska-Tarasiewicz

Kuźmicka

Karpińska

et al. 2005

ANAL. SCI.

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“…The extent of the reaction leading to the formation of the coloured product and the stability of the formed compound also depend on the pH [33]. In addition, previous studies using FeCl 3 as oxidizing agent indicate an acidic media as the optimal condition for the formation of coloured products [34,35].…”

Section: Ph Effectmentioning

confidence: 99%

“…Several oxidants such as Fe , H 2 O 2 , have been reported for this purpose, being iron and its anionic complexes the most used ones [32][33][34]. FeCl 3 is the elected reagent due to the high stability of the intermediate radicals formed.…”

Section: Introductionmentioning

confidence: 99%

Disposable solid state probe for optical screening of chlorpromazine

Guerreiro

Sales

2011

Microchim Acta

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We are presenting a simple, low-cost and rapid solid-state optical probe for screening chlorpromazine (CPZ) in aquacultures. The method exploits the colourimetric reaction between CPZ and Fe(III) ion that occurs at a solid/liquid interface, the solid layer consisting of ferric iron entrapped in a layer of plasticized PVC. If solutions containing CPZ are dropped onto such a layer, a colour change occurs from light yellow to dark pink or even light blue, depending on the concentration of CPZ. Visual inspection enables the concentration of CPZ to be estimated. The resulting colouration was also monitored by digital image collection for a more accurate quantification. The three coordinates of the hue, saturation and lightness system were obtained by standard image processing along with mathematical data treatment. The parameters affecting colour were assessed and optimized. Studies were conducted by visible spectrophotometry and digital image acquisition, respectively. The response of the optimized probe towards the concentration of CPZ was tested for several mathematical transformations of the colour coordinates, and a linear relation was found for the sum of hue and luminosity. The limit of detection is 50 μM (corresponding to about 16 μg per mL). The probe enables quick screening for CPZ in real water samples with prior sample treatment.

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“…The acidity of the reaction medium is another factor significantly influencing the stability of the phenothiazine radical-cation. The radical-cation is stable only in strongly concentrated solutions of acids (2-10 mol/L) [7]. The oxidation processes of phenothiazine derivatives are carried out at relatively low redox potentials.…”

Section: Introductionmentioning

confidence: 99%

A spectrofluorimetric determination of phenothiazine derivatives after their photooxidation or chemical or electrochemical oxidation in a flow injection arrangement

Nesměrák

Červený

Hraníček

et al. 2013

Microchemical Journal

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Effects of salts on the stability of the cationic radical of phenothiazine derivatives

Cited by 19 publications

References 8 publications

Efficient Oxidizing Agents for Determination of 2,10-Disubstituted Phenothiazines

Efficient Oxidizing Agents for Determination of 2,10-Disubstituted Phenothiazines

Disposable solid state probe for optical screening of chlorpromazine

A spectrofluorimetric determination of phenothiazine derivatives after their photooxidation or chemical or electrochemical oxidation in a flow injection arrangement

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