Effects of the Thyroid Hormone on Differentiation, Growth, and Proteolysis in Cultured Muscle Cells during Serum Deprivation.

Doi, Junko; Shinbori, Yuki; Ohtsuka, Akira; Hayashi, Kunioki

doi:10.3177/jnsv.48.265

Cited by 4 publications

(2 citation statements)

References 21 publications

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“…8) Doi et al have also found that serum deprivation induces myofibrillar proteolysis and that insulin and thyroid hormones suppress serum deprivation-induced myofibrillar proteolysis in cultured muscle cells. 17) The main purpose of the present experiments was to determine the proteolytic mechanism(s) involved in a serum deprivation-dependent increase in myofibrillar proteolysis. We measured the mRNA levels of components of the ubiquitinproteasome system (non-lysosomal ATP-dependent proteolysis).…”

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confidence: 99%

Effects of Serum Deprivation on Expression of Proteolytic-Related Genes in Chick Myotube Cultures

Nakashima

Yamazaki

Abé

2005

Bioscience, Biotechnology, and Biochemistry

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confidence: 99%

Effects of Serum Deprivation on Expression of Proteolytic-Related Genes in Chick Myotube Cultures

Nakashima

Yamazaki

Abé

2005

Bioscience, Biotechnology, and Biochemistry

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“…22,23) Recently, Doi et al have also demonstrated that insulin and thyroid hormones suppress myoˆbrillar proteolysis of cultured muscle cells in serum-free medium. 24) When cultured cells are deprived of serum, the rate of intracellular proteolysis increase. [1][2][3][4][5][6][7] Cells in culture show a series of changes in intracellular protein degradation in response to serum deprivation that is similar to alterations in degradation in the tissues of a starved animal.…”

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confidence: 99%

Effects of Serum Deprivation on Myofibrillar Proteolysis in Chick Myotube Cultures

Nakashima¹,

Nonaka²,

Shimizu³

2003

Bioscience, Biotechnology, and Biochemistry

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We examined the eŠects of serum deprivation on myoˆbrillar proteolysis in chick myotubes. Myotubes were incubated with serum-free medium for 24 hours. N t -methylhistidine release, as an index of myoˆbrillar proteolysis, as well as protease activities such as calpain, proteasome, and cathepsins (B＋L and D) activities were increased by serum deprivation. These results indicate that serum deprivation induces calpain, proteaosme, and cathepsins activities, resulting in an increase in myoˆbrillar proteolysis in chick myotubes.

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Managing the Prenatal Environment to Enhance Livestock Productivity

Greenwood¹,

Bell

Vercoe

et al. 2010

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PrefaceGlobal demand for livestock products is expanding and the role of developing countries in meeting this demand is increasing. Nutrition of the reproductive female in livestock production systems in developed and developing countries is a key to satisfying this increased demand because it influences the number, size and survival of offspring, and the frequency with which they are produced. One field of research that is attracting increasing attention is in utero nutrition of the fetus because of evidence that it influences postnatal productivity and health in the long-term.Livestock in the developing world endure unique challenges from their environments, which are generally harsher and less managed than those faced by livestock in the developed countries. A feature of livestock production systems in developing countries is the fluctuation in the amount and quality of feed resources accessible to livestock. The fetus, therefore, is exposed to various challenges that are mostly, but not exclusively, of nutritional origin and that may influence its lifetime performance. The local genotypes within developing countries are unique in that they often have evolved, been selected for, or been exposed to trans-generational environmental effects, which dictate that survival is the overriding production objective. Often, little or no knowledge exists on whether the maternal environment influences the subsequent productive performance of offspring from these genotypes. A better understanding of how fetal development can be enhanced to improve lifetime performance in local genotypes will provide more opportunities to satisfy the increasing demand for livestock products.

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Effects of the Thyroid Hormone on Differentiation, Growth, and Proteolysis in Cultured Muscle Cells during Serum Deprivation.

Cited by 4 publications

References 21 publications

Effects of Serum Deprivation on Expression of Proteolytic-Related Genes in Chick Myotube Cultures

Effects of Serum Deprivation on Expression of Proteolytic-Related Genes in Chick Myotube Cultures

Effects of Serum Deprivation on Myofibrillar Proteolysis in Chick Myotube Cultures

Managing the Prenatal Environment to Enhance Livestock Productivity

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