Efficient synthesis of 1,5-benzodiazepines catalyzed by silica supported 12-tungstophosphoric acid

Abdollahi‐Alibeik, Mohammad; Mohammadpoor‐Baltork, Iraj; Zaghaghi, Zahra; Yousefi, Behrooz H.

doi:10.1016/j.catcom.2008.07.004

Cited by 38 publications

(14 citation statements)

References 36 publications

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“…They have attracted special attention due to their important biological or pharmacological properties [1][2][3][4][5][6][7][8] and their wide field of application in different areas of medicine [9][10][11][12] and agriculture 13 . It was reported that the 1,5-benzodiazepines and its derivatives present interesting pharmacological and therapeutic properties.…”

Section: Introductionmentioning

confidence: 99%

Green and efficient method for the synthesis of 1,5-benzodiazipines using phosphate fertilizers as catalysts under free solvent

Sibous¹,

Ghailane²,

Serrar³

et al. 2017

Mediterr.J.Chem.,

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Three-component reaction in one pot transformation of aldehydes, ethylacetoacetate and o-phenylenediamine was employed for the synthesis, under solvent-free, of 1,5-benzodiazepine derivatives using fertilizers mono-ammonium phosphate (MAP), di-ammonium Phosphate (DAP) and triple super phosphate (TSP) as safe, clean, and recyclable catalysts. The synthesis method seems to be operationally simple and provides access to a variety of 1,5-benzodiazepines with excellent yields in a short reaction time.

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Section: Introductionmentioning

confidence: 99%

Green and efficient method for the synthesis of 1,5-benzodiazipines using phosphate fertilizers as catalysts under free solvent

Sibous¹,

Ghailane²,

Serrar³

et al. 2017

Mediterr.J.Chem.,

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“…The use of solid acid catalysts in organic transformations has attracted considerable attention because of their advantages such as the ease of recovery, reusability, ease of handling and environmental considerations [20]. Apart from various types of solid acids, 12-tungstophosphoric acid (TPA) as a Keggin type heteropoly acid has attracted considerable attention because of its high Brønsted acidity and thermal stability [21,22].…”

mentioning

confidence: 99%

“…Various mineral oxides such as silica [20], alumina [25], titania [26] and zirconia [27] have been used as the support for TPA in many catalytic reactions. Recent developments on mesoporous molecular sieves provide the possibility of using new high surface area supports for the immobilization of TPA.…”

mentioning

confidence: 99%

“…However, the use of bulk TPA has encountered some difficulties, which have reduced its application in some organic transformations. Some of the major problems associated with TPA in bulk form include low surface area (\10 m 2 g -1 ) [23], production of bulky residue in the reaction media, specially with amino functional groups [20], rapid deactivation and relatively poor stability [24].…”

mentioning

confidence: 99%

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12-Tungstophosphoric acid supported on nano sized MCM-41 as an efficient and reusable solid acid catalyst for the three-component imino Diels–Alder reaction

Abdollahi‐Alibeik

Pouriayevali

2011

Reac Kinet Mech Cat

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One pot three-component imino Diels-Alder reactions of various types of aldehydes, aniline and dihydropyrane were studied in the presence of nano sized MCM-41 supported 12-tungstophosphoric acid (TPA) as solid acid catalyst. MCM-41 as solid support was synthesized in nano size and the catalysts with different loading amounts of TPA (5-30 wt%) were prepared and characterized by XRD, FT-IR and SEM techniques. The results confirm a good dispersion of the heteropoly acid on the solid supports and based on the experimental results, the catalyst with 10 wt% heteropoly acid shows the best catalytic activity using 0.5 mol% heteropoly acid relative to the aldehyde. The recovery experiments show that the catalyst is reusable after calcination without significant loss in its activity.

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“…There were many methods known, which were considered for up-gradation in urgencies. Many catalyst reported in literatures with significant boundaries were Silica supported 12-tungstophosphoric acid [3], boron trifluoride ether complex [4], Ytterbium triflate [5], Magnesium oxide/phosphorus oxychloride [6]. All methods in literature has its distinct use and also has some limitations like green aproach, reusability, etc.…”

Section: Introductionmentioning

confidence: 99%

Reusable Nanocatalyst: Zirconia and Sulfated Zirconia

Gondaliya

Maheta

Mamtora

et al. 2014

ILCPA

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ABSTRACT1,5-benzodiazepines have been synthesized by Nano Zirconia and Nano Sulfated Zirconia in solvent free conditions. Synthesis was carried out by conventional as well as microwave method. Benzodiazepines were synthesized by reacting o-phenylenediamine and few ketones in the presence of catalytic amount of Nanoparticles. Particles used were sized in between 53-100 nm. Nanoparticles were characterized by FT-IR, DLS and powder XRD analysis.

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Efficient synthesis of 1,5-benzodiazepines catalyzed by silica supported 12-tungstophosphoric acid

Cited by 38 publications

References 36 publications

Green and efficient method for the synthesis of 1,5-benzodiazipines using phosphate fertilizers as catalysts under free solvent

Green and efficient method for the synthesis of 1,5-benzodiazipines using phosphate fertilizers as catalysts under free solvent

12-Tungstophosphoric acid supported on nano sized MCM-41 as an efficient and reusable solid acid catalyst for the three-component imino Diels–Alder reaction

Reusable Nanocatalyst: Zirconia and Sulfated Zirconia

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