Enantioselective vanadium-catalyzed transformations. An update

Integrated experimental/computational approaches to characterize the systems formed by vanadium with proteins and enzymes

“…18,24,27 On the other hand, the artificial metalloenzyme (ArM) community could exploit the high availability of V, its higher biocompatibility compared with heavy metals, and its catalytic properties toward asymmetric oxidation and C-C coupling reactions, among others. [28][29][30][31] However, after pioneering studies in the late 1990s by Allenmark 32 and Wever 33 on semi-synthetic haloperoxidases, and by Sheldon [34][35][36] on phytase, little was done in the field of V-based ArMs. 37,38 The reasons for little progress being made in the above mentioned promising fields could be partially ascribed to the lack of structural and mechanistic knowledge of V-containing biosystems, which is one of the main factors for which VCs are not or rarely considered by pharmaceutical companies.…”

“…The V-based homogeneous catalysts demonstrated high efficiency in epoxidations, sulfoxidations, haloperoxidations, C-C bond, Mannich-type processes, polymerizations and bond cleavage, including asymmetric and stereoselective processes. [29][30][31] Moreover, the presence of vanadium in natural biocatalysis, such as in haloperoxidases (HPOs) and nitrogenases, 45 makes vanadium a perfect candidate to be incorporated into artificial metalloenzyme.…”

Oxido- and Dioxido-Vanadium(V) Complexes Supported on Carbon Materials: Reusable Catalysts for the Oxidation of Cyclohexane

“…Vanadium compounds are active catalysts towards several oxidative organic transformations [1][2][3][4][5][6][7][8][9][10][11][12]. They are often used as homogeneous catalysts and can exhibit high activity (in terms of yield) and enantioselectivity [1][2][3][4][5][6][7][8][9][10][11][12].…”

“…Vanadium compounds are active catalysts towards several oxidative organic transformations [1][2][3][4][5][6][7][8][9][10][11][12]. They are often used as homogeneous catalysts and can exhibit high activity (in terms of yield) and enantioselectivity [1][2][3][4][5][6][7][8][9][10][11][12]. However, the homogenous catalytic systems present some limitations concerning catalyst separation from the reaction products, recycling and potential application to continuous flow processes.…”

Vanadium(V) Complex-Catalyzed One-Pot Synthesis of Phenanthridines via a Pictet-Spengler-Dehydrogenative Aromatization Sequence

“…Organometallic vanadium(V) complexes have been employed in the development of a wide range of organic reactions [16][17][18][19][20][21][22][23]. Their high valency and ability to exist in multiple oxidation states enable vanadium complexes to act as Lewis acid and/or redox catalysts.…”