Encapsulation of therapeutic lavender oil in an electrolyte assisted polyacrylonitrile nanofibres for antibacterial applications

Kandasubramanian, Balasubramanian; Kodam, Kisan M.

doi:10.1039/c4ra09425e

Cited by 75 publications

(56 citation statements)

References 56 publications

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“…So far a wide variety of essential oils have been electrospun, including cinnamon [39][40][41][42][43][44], oregano [45][46][47][48], peppermint [44,[49][50][51][52], clove [41,[53][54][55][56][57], thyme [58][59][60][61], lavender [62][63][64], eucalyptus [65], ginger [66], tea tree [67,68], Manuka [68], black pepper [69], and sage [69]. This review focuses on works that report the addition of EOs to polymeric solutions before conducting the electrospinning process.…”

Section: Electrospun Fibres Containing Eos and Their Applicationsmentioning

confidence: 99%

“…The main components of L. angustifolia and L. latifolia EOs are oxygenated monoterpenes: linalool (25-38%), linalyl acetate (25-45%) and lavandulyl acetate (3.4-6.2%) for L. angustifolia EO; linalool (34-50%), 1,8-cineole (16-39%) and camphor (10-20%) for L. latifolia EO [101]. So far, lavender EOs have been encapsulated in electrospun fibres of sodium alginate [62], polyurethane [63], and polyacrylonitrile [64], to promote wound healing and skin regeneration. Polyurethane (Tecoflex) fibres containing different concentrations of silver nanoparticles (1-7% w/w) and lavender EO (5-20% w/w) have been electrospun at a voltage of 15 kV, flow rate of 0.5 mL/h and needle-to-collector distance of 15 cm [63].…”

Section: Lavender Essential Oilmentioning

confidence: 99%

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Electrospinning of Essential Oils

Mele

2020

Polymers

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The extensive and sometimes unregulated use of synthetic chemicals, such as drugs, preservatives, and pesticides, is posing big threats to global health, the environment, and food security. This has stimulated the research of new strategies to deal with bacterial infections in animals and humans and to eradicate pests. Plant extracts, particularly essential oils, have recently emerged as valid alternatives to synthetic drugs, due to their properties which include antibacterial, antifungal, anti-inflammatory, antioxidant, and insecticidal activity. This review discusses the current research on the use of electrospinning to encapsulate essential oils into polymeric nanofibres and achieve controlled release of these bioactive compounds, while protecting them from degradation. The works here analysed demonstrate that the electrospinning process is an effective strategy to preserve the properties of essential oils and create bioactive membranes for biomedical, pharmaceutical, and food packaging applications.

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Section: Electrospun Fibres Containing Eos and Their Applicationsmentioning

confidence: 99%

Section: Lavender Essential Oilmentioning

confidence: 99%

Electrospinning of Essential Oils

Mele

2020

Polymers

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“…Due to its importance in textile, water treatment or medicinal industries, many strategies are found to develop antimicrobial PAN materials in the latest years [9,[16][17][18][19][20][21][22][23][24]. For instance, recent research has focused on antimicrobial PAN nanofibers by adding silver nanoparticles [22,25,26], blends with other bioactive polymers [20,21,27], composites [19,23,28,29], chemical modification [30] or even adding antibiotics [18,22,25,31]. However, there exist only a few reported examples of antimicrobial PAN copolymers [32][33][34].…”

Section: Introductionmentioning

confidence: 98%

Copolymers of acrylonitrile with quaternizable thiazole and triazole side-chain methacrylates as potent antimicrobial and hemocompatible systems

et al. 2015

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“…36 Electrospun nanofibers of Polyacrylonitrile (PAN) containing lavender oil have been recently developed for antibacterial and drug delivery applications. 37 Although both inorganic and organic antiseptic agents have shown a certain degree of success for various medical applications, the use of all-natural medicinal extracts, such as LO, can further boost pharmaceutical applications and improve patient recovery and quality of life.…”

Section: Introductionmentioning

confidence: 99%

Alginate–lavender nanofibers with antibacterial and anti-inflammatory activity to effectively promote burn healing

et al. 2016

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This is an Accepted Manuscript, which has been through the Royal Society of Chemistry peer review process and has been accepted for publication.Accepted Manuscripts are published online shortly after acceptance, before technical editing, formatting and proof reading. Using this free service, authors can make their results available to the community, in citable form, before we publish the edited article. We will replace this Accepted Manuscript with the edited and formatted Advance Article as soon as it is available.You can find more information about Accepted Manuscripts in the Information for Authors. One of the current challenges in wound care is the development of multifunctional dressings that can both protect the wound from external agents and promote the regeneration of the new tissue. Here, we show the combined use of two naturally derived compounds, sodium alginate and lavender essential oil, for the production of bioactive nanofibrous dressings by electrospinning, and their efficacy for the treatment of skin burns induced by midrange ultraviolet radiation (UVB). We demonstrate that the engineered dressings reduce the risk of microbial infection of the burn, since they stop the growth of Staphylococcus aureus. Furthermore, they are able to control and reduce the inflammatory response that is induced in human foreskin fibroblasts by lipopolysaccharides, and in rodents by UVB exposure. In particular, we report a remarkable reduction of pro-inflammatory cytokines when fibroblasts or animals are treated with the alginate-based nanofibers. The down-regulation of cytokines production and the absence of erythema on the skin of the treated animals confirm that the here described dressings are promising as advanced biomedical devices for burn management.

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Encapsulation of therapeutic lavender oil in an electrolyte assisted polyacrylonitrile nanofibres for antibacterial applications

Abstract: Electrospinning, a feasible nanotechnology, has been exploited to engineer polyacrylonitrile (PAN) nanofibrous mats enclosing a representative hydrophobic drug like essential oil of lavender.

Cited by 75 publications

References 56 publications

Electrospinning of Essential Oils

Electrospinning of Essential Oils

Copolymers of acrylonitrile with quaternizable thiazole and triazole side-chain methacrylates as potent antimicrobial and hemocompatible systems

Alginate–lavender nanofibers with antibacterial and anti-inflammatory activity to effectively promote burn healing

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