Enzymes from carbohydrase group destroy biofilm matrix of gram-positive and gram-negative bacteria

Abstract

The effect of enzymes carbohydrases exopolysaccharide matrix of biofilms formed by gram-positive and gram-negative bacteria on abiotic surfaces was studied. The ability of a mixture of carbohydrase enzymes (hydrolases and lyases) to completely destroy the matrix of biofilms formed by gram-positive and gram-negative bacteria causing health-associated infections has been confirmed. An optimal mixture of carbohydrases possesed high anti-biofilm activity even when employed in relatively small concentrations and at a brief exposure time.