Epidemiology, Clinical Manifestations, and Outcomes ofStreptococcus suisInfection in Humans

Abstract

Infection occurs mainly in Asia; occupational and food exposures are the primary risk factors.

Molecular Basis of Resistance to Selected Antimicrobial Agents in the Emerging Zoonotic Pathogen Streptococcus suis

“…Since the first human case was described in 1968 in Denmark (5), over 1,500 cases of S. suis infections in humans have been reported, mainly from Thailand, Vietnam, and China. The incidence of human infections has been described sporadically in Europe and North America (6). In Korea, until recently, S. suis infection had been described only in swine, mainly from slaughter pigs (7) and diseased pigs (8).…”

A Decennium of Etiology and Antimicrobial Susceptibility Patterns in Patients with Infective Endocarditis at a University Hospital, Thailand

“…Studies in Brazil and Belgium showed only 1.6% and 0.9% of Group B streptococcus IE, respectively (4,20). A meta-analysis showed that the prevalence of Streptococcus suis infection is highest in Asia, particularly in Thailand (36%) (21). There were different data for antimicrobial susceptibilities among Streptococcus spp., while Streptococcus suis had the highest MIC 90 .…”

Predominance of Streptococcus suis ST1 and ST7 in human cases in China, and detection of a novel sequence type, ST658

“…1 Human S. suis infections have been reported from more than 30 countries and/or regions, and the number of cases has increased considerably in the last decade, particularly in southeast Asian countries, such as China, Thailand, and Vietnam. [1][2][3] While most sporadic S. suis infections in humans have been reported to be occupational, especially in Western countries, 2 outbreaks in China (Sichuan in 2005, and Jiangsu in 1998) and one in Thailand (Phayao in 2007) were reported. The outbreaks aroused considerable public health concern about S. suis emerging as a zoonotic agent.…”

“…The outbreaks aroused considerable public health concern about S. suis emerging as a zoonotic agent. 2 In a global estimate, the numbers of human infections of S. suis reported from China, Thailand and Vietnam account for 22-36% of all cases reported worldwide. 2 Nearly 97% of all human cases of streptococcosis relate to serotype 2, but it has become increasingly important to genetically classify S. suis isolates according to their sequence type (ST) by multilocus sequence typing (MLST).…”

“…2 In a global estimate, the numbers of human infections of S. suis reported from China, Thailand and Vietnam account for 22-36% of all cases reported worldwide. 2 Nearly 97% of all human cases of streptococcosis relate to serotype 2, but it has become increasingly important to genetically classify S. suis isolates according to their sequence type (ST) by multilocus sequence typing (MLST). 1,4 To date, 33 and 10 STs have been recorded in Thailand and Vietnam, respectively (cf.…”