"Estudo comparativo do desempenho em testes neuropsicológicos de pacientes com diagnóstico de doença de Alzheimer e demência vascular"

Although the main initial deficit is considered to be in the memory domain, an early impairment of executive functions is also found in AD where these deficits are correlated to functional impairment. Ecological tests are more indicated to evaluate executive impairment, and are better able to assist in treating AD patients than more commonly used tests.ObjectivesThe aim of this preliminary study is to verify the performance in executive functions using the Behavioural Assessment of the Dysexecutive Syndrome (BADS) in elder controls and mild AD patients, and to analyze its applicability in our environment.MethodsThe BADS was performed by 17 healthy elders and 17 early AD patients matched for age, schooling and gender.ResultsThere were significant differences among controls and AD patients on MMSE scores, and in measures of executive functions, memory, and motor speed. Some sub items of BADS (rule shift cards, modified six elements, total score, standard, standard by age and overall classification by age) were also different between groups. Differences were also significant on the Dysexecutive Questionnaire (DEX) of BADS self-ratings and other-ratings.ConclusionBADS was efficacious in detecting executive deficits in this sample, as confirmed by other executive functions tests applied.

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“…There was no difference on the CLOX 1, which evaluates executive function, in contrast with previous reports showing discrepant findings. 38 …”

Section: Discussionmentioning

confidence: 99%

Behavioural assessment of the dysexecutive syndrome (BADS) in healthy elders and Alzheimer´s disease patients: preliminary study

Canali

Brucki

Bueno

2007

Dement. neuropsychol.

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“…Some studies have shown that these tests are highly sensitive for diagnosing dementia and detecting executive impairment in early AD. 3,4,22,23,[26][27][28] These results demonstrate early EF alterations in early AD patients, who also performed worse than the control group on the BADS (all subtests), and were mostly rated as impaired. A similar result was found by Amanzio et al using the BADS on AD patients as part of a cognitive testing procedure to examine the relationship between performance on the latter and comprehension of metaphors.…”

Section: Discussionmentioning

confidence: 83%

Reliability study of the Behavioral Assessment of the Dysexecutive Syndrome adapted for a Brazilian sample of older-adult controls and probable early Alzheimer's disease patients

Canali

Brucki

Bertolucci

et al. 2011

Rev. Bras. Psiquiatr.

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Objective: Ecological tests are useful in assessing executive function deficits and may be of value in appraising response to treatment in Alzheimer's disease patients. Our aims were to examine executive function using the Behavioral Assessment of the Dysexecutive Syndrome for a Brazilian sample of older-adult controls and probable early Alzheimer's disease patients, and verify the applicability of this test battery. Method: Forty-one older-adult controls were matched with mild Alzheimer's disease patients by age, education, and gender. Results: There significant inter-group differences in overall profile and almost all subtests except temporal judgment, time spent on planning the first and second Zoo Map visit, number of errors when copying drawings, naming pictures and Six Modified Elements arithmetic, and dysexecutive questionnaire self-rating. The Behavioral Assessment of the Dysexecutive Syndrome item that best discriminated controls from patients was the Modified Six Elements -adapted (general index), with a sensitivity of 80% and specificity of 90%, (AUC = 0.91, p < 0.001). Conclusion: Behavioral Assessment of the Dysexecutive Syndrome was effective in detecting executive function deficits in mild Alzheimer's disease patients, particularly the task switching, time monitoring, and rule-shift subtests. Descriptors

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“…The test can be used for assessing executive functions in elderly people with normal cognition or with cognitive impairment, to identify specific subtypes of mild cognitive impairment and the risk of dementia conversion, as well as in the context of the authors’ initial idea, i.e., to establish functional status, self-care deficits and to predict problematic behaviors or psychiatric disturbances of demented subjects. 2 , 12 - 15 …”

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confidence: 99%

EXIT25 - Executive interview applied to a cognitively healthy elderly population with heterogeneous educational background

Matioli

Caramelli

Marques

et al. 2008

Dement. neuropsychol.

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Education interferes with the performance in most cognitive tests, including executive function assessment.ObjectiveTo investigate the effects of education on the performance of healthy elderly on the Brazilian version of the Executive Interview (EXIT25).MethodsThe EXIT25 was administered to a sample of 83 healthy elderly. The subjects were also submitted to the Mini-Mental State Examination (MMSE), a delayed recall test, clock drawing and category fluency (animals/min) tests in order to rule out cognitive impairment. The Geriatric Depression Scale (GDS) was employed to exclude clinically-relevant depressive symptoms. The total sample was divided into three groups according to educational level: G1 (1–4 years), G2 (5–8 years) and G3 (>8 years).ResultsThe mean values for age, educational level, MMSE and EXIT25 scores of all subjects were 72.2, 7.5, 27.6 and 6.9, respectively. The scores on the EXIT25 for each group were: G1=8.3, G2=5.9 and G3=5.8. There was a statistical difference between the performance of G1 and the other two groups on the EXIT25.ConclusionsThe Brazilian version of the EXIT25 proved straightforward to administer. The performance of this sample of healthy elderly on the test was significantly influenced by educational level.

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"Estudo comparativo do desempenho em testes neuropsicológicos de pacientes com diagnóstico de doença de Alzheimer e demência vascular"

Cited by 6 publications

References 22 publications

Behavioural assessment of the dysexecutive syndrome (BADS) in healthy elders and Alzheimer´s disease patients: preliminary study

Behavioural assessment of the dysexecutive syndrome (BADS) in healthy elders and Alzheimer´s disease patients: preliminary study

Reliability study of the Behavioral Assessment of the Dysexecutive Syndrome adapted for a Brazilian sample of older-adult controls and probable early Alzheimer's disease patients

EXIT25 - Executive interview applied to a cognitively healthy elderly population with heterogeneous educational background

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