Evaluation of in vitro corrosion resistance and in vivo osseointegration properties of a FeMnSiCa alloy as potential degradable implant biomaterial

Trincă, Lucia Carmen; Burtan, L. C.; Mareci, Daniel; Fernández-Pérez, B.M.; Stoleriu, Iulian; Stanciu, Teodor; Stanciu, Sergiu; Solcan, Carmen; Izquierdo, Javier

doi:10.1016/j.msec.2020.111436

Cited by 27 publications

(12 citation statements)

References 67 publications

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“…Generally, there are several basic types of alloy additives: Noble metals as a second phase composite, like Pd [ 36 , 126 , 127 ], Cu [ 73 , 128 ], Ag [ 125 , 129 , 130 ] cause local galvanic corrosion, because of their high electrochemical potential. The addition of silicon drew the attention of scientists because devices made of the Fe-Mn-Si alloy have shape memory and a higher corrosion rate [ 54 , 68 , 72 , 83 , 131 , 132 ]. Elements from the second group, Mg and Ca, have strong negative electrochemical potentials (Mg = −2.38 V vs. SHE, Ca = −2.76 V vs. SHE).…”

Section: Iron Materials Modificationsmentioning

confidence: 99%

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Biodegradable Iron-Based Materials—What Was Done and What More Can Be Done?

2021

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Iron, while attracting less attention than magnesium and zinc, is still one of the best candidates for biodegradable metal stents thanks its biocompatibility, great elastic moduli and high strength. Due to the low corrosion rate, and thus slow biodegradation, iron stents have still not been put into use. While these problems have still not been fully resolved, many studies have been published that propose different approaches to the issues. This brief overview report summarises the latest developments in the field of biodegradable iron-based stents and presents some techniques that can accelerate their biocorrosion rate. Basic data related to iron metabolism and its biocompatibility, the mechanism of the corrosion process, as well as a critical look at the rate of degradation of iron-based systems obtained by several different methods are included. All this illustrates as the title says, what was done within the topic of biodegradable iron-based materials and what more can be done.

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Section: Iron Materials Modificationsmentioning

confidence: 99%

“…The addition of silicon drew the attention of scientists because devices made of the Fe-Mn-Si alloy have shape memory and a higher corrosion rate [ 54 , 68 , 72 , 83 , 131 , 132 ].…”

Section: Iron Materials Modificationsmentioning

confidence: 99%

Biodegradable Iron-Based Materials—What Was Done and What More Can Be Done?

2021

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“…The degradation rates of Fe–35Mn alloy (0.42 ± 0.03 mm/year vs 0.062 mm/year) and Zn–4Ag (silver) alloy (17.38 ± 0.78 μm/year vs 4.80 ± 0.82 μm/year) were significantly higher than those of their pure metals respectively [ 49 , 50 ]. For quaternary alloys, a study by Trincă et al.’s [ 51 ] showed the ability of FeMnSiCa alloys to degrade at higher corrosion rate when compared with base FeMnSi alloys. The degradation of metals in vivo is not catalyzed by enzymes but through electrochemical corrosion.…”

Section: Formation Of Composites To Optimize Materials Propertiesmentioning

confidence: 99%

Biologically modified implantation as therapeutic bioabsorbable materials for bone defect repair

et al. 2022

Regenerative Therapy

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For decades, researches have concentrated on the mechanical properties, biodegradation, and biocompatibility of implants used in the therapy of large size bone defect. In vivo studies demonstrate that bioabsorbable bone substitute materials can reduce the risk of common symptoms such as inflammation and osteonecrosis caused by bio-inert materials after long-term implantation. Several organic, inorganic, and composite materials have been approved for clinical application, based on their unique characteristics and advantages. Although some artificial bioabsorbable bone substitute materials have been used for years, there are still some disadvantages existing, such as low mechanical strength, high brittleness, and low degradation rate. Therefore, novel bioabsorbable composite materials biomaterials have been developed for bone defect repair. In this review, we provide an overview of the development of artificial bioabsorbable bone substitute materials and highlight the advantages and disadvantages. Furthermore, recent advances in bioabsorbable bone substitute materials used in bone defect repair are outlined. Finally, we discuss current challenges and further developments in the clinical application of bioabsorbable bone substitute materials.

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“…Therefore, the Fe30Mn6Si alloy is more prone to corrosion. The OCP shifted in the negative direction after exposure to SBF solution, suggesting the dissolution of the sample surface . Then, the OCP stabilized at certain values with further immersion, which indicated that the dissolution process had a stationary state.…”

Section: Resultsmentioning

confidence: 93%

“…The OCP shifted in the negative direction after exposure to SBF solution, suggesting the dissolution of the sample surface. 38 Then, the OCP stabilized at certain values with further immersion, which indicated that the dissolution process had a stationary state. In addition, the OCP of the Fe30Mn6Si alloy showed a faster decrease rate in the initial stage compared to Fe and Fe30Mn, implying a poor passivation effect.…”

Section: Resultsmentioning

confidence: 99%

Stress-Induced Dual-Phase Structure to Accelerate Degradation of the Fe Implant

Shuai

Zhong

Dong

et al. 2022

ACS Biomater. Sci. Eng.

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Fe is considered as a potential candidate for implant materials, but its application is impeded by the low degradation rate. Herein, a dual-phase Fe30Mn6Si alloy was prepared by mechanical alloying (MA). During MA, the motion of dislocations driven by the impact stress promoted the solid solution of Mn in Fe, which transformed α-ferrite into γ-austenite since Mn was an austenite-stabilizing element. Meanwhile, the incorporation of Si decreased the stacking fault energy inside austenite grains, which tangled dislocations into stacking faults and acted as nucleation sites for ε-martensite. Resultantly, Fe30Mn6Si powder had a dualphase structure composed of 53% γ-austenite and 47% εmartensite. Afterward, the powders were prepared into implants by selective laser melting. The Fe30Mn6Si alloy had a more negative corrosion potential of −0.76 ± 0.09 V and a higher corrosion current of 30.61 ± 0.41 μA/cm 2 than Fe and Fe30Mn. Besides, the long-term weight loss tests also proved that Fe30Mn6Si had the optimal degradation rate (0.25 ± 0.02 mm/year).

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Evaluation of in vitro corrosion resistance and in vivo osseointegration properties of a FeMnSiCa alloy as potential degradable implant biomaterial

Cited by 27 publications

References 67 publications

Biodegradable Iron-Based Materials—What Was Done and What More Can Be Done?

Biodegradable Iron-Based Materials—What Was Done and What More Can Be Done?

Biologically modified implantation as therapeutic bioabsorbable materials for bone defect repair

Stress-Induced Dual-Phase Structure to Accelerate Degradation of the Fe Implant

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