Evaluation of the Antioxidant Activities of Ya-hom Intajak, a Thai Herbal Formulation, and its Component Plants

Tuekaew, Jantanarak; Siriwatanametanon, Nisarat; Wongkrajang, Yuvadee; Temsiririrkkul, Rungravi; Jantan, Ibrahim

doi:10.4314/tjpr.v13i9.14

Cited by 24 publications

(24 citation statements)

References 16 publications

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“…In previous studies, the methanolic macerate of Anacyclus clavatus flowers yielded about 6,78 ± 0,23% [18]. Whereas, the A. pyrethrum ethanolic macerate, from Spain and India, recorded yields of 4,34% and 11,53% respectively [19,20]. In fact, rare works mentioned the yields of the different fractions prepared according to our methodology.…”

Section: Yield Of Phenolic Extractsmentioning

confidence: 80%

“…It also seems that the hydromethanolic extracts of the aerial and subterranean parts respectively of A. clavatus (Algeria) and A. pyrethrum (India) had a phenol content of 71,09 ± 3,84 and 62,89 ± 0,43 mg EAG/g extract respectively [23,24]. As a reminder, ethanolic extracts from roots of the same species, A. pyrethrum from India and Spain, were found to be rich in total polyphenols estimated at 159,63 ± 0,52 and 42,21 ± 1,59 mg EAG/g extract respectively [19,25].…”

Section: Dosage Of Total Phenolsmentioning

confidence: 94%

See 1 more Smart Citation

Total phenolic and flavonoid contents of Anacyclus pyrethrum Link plant extracts and their Antioxidant activity

Elazzouzi¹,

Zekri²,

Zair³

et al. 2019

Karbala International Journal of Modern Science

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Section: Yield Of Phenolic Extractsmentioning

confidence: 80%

Section: Dosage Of Total Phenolsmentioning

confidence: 94%

Total phenolic and flavonoid contents of Anacyclus pyrethrum Link plant extracts and their Antioxidant activity

Elazzouzi¹,

Zekri²,

Zair³

et al. 2019

Karbala International Journal of Modern Science

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“…Previously, antioxidant property of C.sappan was investigated and reported that the activity was according to the phenolic compounds (19) such as alkaloid, tannins, steroids, and flavonoids (14,20), which most of flavonoid compounds in the extracts are flavone and flavonol (21). Most of these compounds are not soluble in water.…”

Section: Discussionmentioning

confidence: 99%

Antioxidant activity and potential of <i>Caesalpinia sappan </i>aqueous extract on synthesis of silver nanoparticles

Suwan

Wanachantararak

Khongkhunthian

et al. 2018

DD&T

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Nowadays, silver nanoparticles (AgNPs) are of high interest due to their particular properties and wide applications. AgNPs are used to inhibit many pathogenic including bacteria such as Staphylococcus aureus, Escherichia coli, Salmonella enteritidis, and Pseudomonas aeruginosa (1-3) and fungi like Aspergillus and Candida spp. (4,5). AgNPs can be synthesized by redox reaction of silver salt as a precursor and a reducing agent from synthetic chemicals. Recently, the ecofriendly process of AgNPs production was developed using reducing agents from natural sources like plants (5), algae (6), and microorganisms (7). Caesalpinia sappan is a plant belongs to familily Leguminosae. It is wildly distributed and cultivated in Southeast Asia, Africa and the America (8). The wood of C. sappan contains several phytochemicals in alkaloids, phenolics, flavonoids, and glycosides (9). The major active compound of C. sappan is brazilin and brazilein, an oxidized from of brazilin (10,11). Many biological activities from different parts of C. sappan have been reported such as antioxidant activity from heart woods (12), antihelmintic property from leaves (13), and antimicrobial activity from barks (14). The aim of this study was to synthesize AgNPs Summary The aim of this study was to investigate the antioxidant activity of Caesalpinia sappan aqueous extract (CE) and its potential on synthesis of silver nanoparticles (AgNPs). The antioxidant activity of CE was investigated using ferric reducing antioxidant power (FRAP) assay and two radical scavenging methods using 2,20-azinobis-(3-ethylbenzothiazoline-6sulfonic acid) diammonium salt (ABTS) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) as free radicals. Silver nitrate (AgNO 3) was used as precursor for the synthesis of AgNPs. Effects of AgNO 3 concentration, reaction temperature, and duration of reaction were investigated. The obtained AgNPs was characterized using UV-Vis and photon correlation spectrophotometers. The antimicrobial activity of AgNPs was studied by means of diffusion method. The results from FRAP demonstrated that CE had high reducing property of 78.7 ± 2.4 mM Fe 2+ /mg. The trolox equivalent antioxidant capacity of CE determined by ABTS was 64.8 ± 4.2 µM/mg. The concentration of CE that can inhibit 50% of DPPH radicals (IC 50) was 51.2 ± 3.2 µM. These results indicated that CE possesses strong antioxidant and reducing activities. The present study also showed that CE can act as reducing agent to produce AgNPs. The concentration of AgNO 3 , reaction temperature, and reaction time play an important role on the particles size and zeta potential of the obtained AgNPs. The antimicrobial activity of the AgNPs against Escherichia coli, Candida albicans, and Streptococcus mutants was stronger than against Staphylococcus aureus.

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“…Nine additional articles were identified through manual searches of the references, bibliographies and consultations with experts. This yielded 24 articles which met the inclusion criteria including 2 in vitro cell lines or bacteria (Sripanidkulchai et al, 2007;Tepsuwan et al, 2011), 3 in vitro cell-free (Channarong et al, 2012;Nalinratana et al, 2014;Tuekaew et al, 2014), 5 in vitro animal tissue studies (Chantharangsikul et al, 2009;Nonthasawadsri et al, 2015;Nusuetrong et al, 2012;Pataloong and Sawasdimongkol, 1995;Suvitayavat et al, 2005b), 13 in vivo animal studies (Chavalittumrong et al, 2009;Intayoong, 2006;Jariyapongskul et al, 2006;Kengkoom and Ampawong, 2015;Kengkoom et al, 2012;Matangkasombat, 1974;Nernpermpisooth et al, 2015;Sirisangtragul and Sripanidkulchai, 2013;Sirisangtrakul and Sripanidkulchai, 2011;Suvitayavat et al, 2004;Suvitayavat et al, 2005a;Thongpraditchote et al, 1999) and 1 human study (Suvitayavat et al, 2005) (Fig 1).…”

Section: Search Resultsmentioning

confidence: 99%

“…Cell-free studies rated Yahoms as moderately high phenolic content as judged by as high reducing capacities (Channarong et al, 2012;Nalinratana et al, 2014;Tuekaew et al, 2014) (Table 3). But how these translate to the in vivo environment is unclear.…”

Section: Pharmacological Effects Of Yahommentioning

confidence: 99%

Efficacy and safety of “Yahom” as a traditional Thai herbal therapy: A systematic review

Chootip

Chaiyakunapruk

Soonthornchareonnon

et al. 2017

Journal of Ethnopharmacology

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Most studies supported declared objectives relating to perceived Yahom actions, but lacked background demonstrating clinical efficacy, and mechanistic data that would validate conclusions. Our study suggests that research into traditional medicinal herbs needs underpinning by appropriate clinical interventions and pharmacovigilance, thereby optimising efficacy and minimizing toxicity by combining traditional wisdom and modern testing.

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Evaluation of the Antioxidant Activities of Ya-hom Intajak, a Thai Herbal Formulation, and its Component Plants

Abstract: FRAP (r = 0.908, p < 0.01) and DPPH activities (r = 0.648, p < 0.01

Cited by 24 publications

References 16 publications

Total phenolic and flavonoid contents of Anacyclus pyrethrum Link plant extracts and their Antioxidant activity

Total phenolic and flavonoid contents of Anacyclus pyrethrum Link plant extracts and their Antioxidant activity

Antioxidant activity and potential of <i>Caesalpinia sappan </i>aqueous extract on synthesis of silver nanoparticles

Efficacy and safety of “Yahom” as a traditional Thai herbal therapy: A systematic review

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