Evaluation of the Antioxidant activity of the roots and Rhizomes of<i>Cyperus rotundus</i>L.

Pal, D.K.; Dutta, Shanti Chaya

doi:10.4103/0250-474x.25731

Cited by 40 publications

(27 citation statements)

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“…Non-enzymatic glycosylation of haemoglobin is an oxidation reaction and an antioxidant can counter this reaction, thereby preventing the process of glycosylation. Since GW demonstrated significant antioxidant potential, it can prevent haemoglobin glycosylation as well [15,21]. Glucose uptake assay by yeast cells showed 64% increase in glucose uptake when treated with GW.…”

Section: Discussionmentioning

confidence: 99%

Antidiabetic and Antioxidant Potential of GancidinW from Streptomyces Paradoxus VITALK03

Ravi¹,

Ragunathan²,

Каннабиран³

2017

TOBCJ

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Background:The aim of the present study was to analyse the antidiabetic and antioxidant potential of GancidinW (GW) extracted from Streptomyces paradoxus VITALK03. Materials and Methods:Antidiabetic potential of GW was evaluated by assay of α-amylase and α-glucosidase inhibitory activity; haemoglobin glycosylation and yeast glucose uptake. The antioxidant potential of GW was assessed by 2,2-Diphenyl-1-picrylhydrazyl (DPPH) assay, 2,2′azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical cation decolorization assay and superoxide assay. The inhibition of α-amylase and α-glucosidase by GW was also studied by in Silico molecular docking analysis. Results:GW (1mg/ml) showed 69.32% of α-amylase and 54.04% of α-glucosidase inhibitory activity. GW (1mg/ml) prevented haemoglobin glycosylation up to 30.92% and the glucose uptake by yeast cells was increased up to 64.38%. The binding interaction GW with αamylase showed the least free binding energy of -6.09Kcal/mol and -7.53Kcal/mol with α-glucosidase by docking studies. GW also demonstrated moderate antioxidant activity in all the antioxidant assays performed. Conclusion:The results of this study suggests that the antidiabetic and antioxidant potential of GW can be probed further to develop GW as effective antidiabetic agent.

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Section: Discussionmentioning

confidence: 99%

Antidiabetic and Antioxidant Potential of GancidinW from Streptomyces Paradoxus VITALK03

Ravi¹,

Ragunathan²,

Каннабиран³

2017

TOBCJ

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“…HG is an in vitro non-enzymatic method based on an oxidation reaction where an antioxidant is expected to inhibit the reaction [27]. Each value is a mean of three replicates ± SE.…”

Section: Hg Assaymentioning

confidence: 99%

In Vitro Regulation of Non-enzymatic Antioxidant Efficiency of Momordica dioica Roxb by Elicitation and Salt Stress

K¹

2014

Med Aromat Plants

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“…Cyperus rotundus possesses anti-oxidant, antiobesity, anti-candida, anti-inflammatory, anti-diabetic, antidiarrhoeal, anti-mutagenic, anti-microbial, anti-bacterial, antipyretic, cytotoxic & apoptotic, cytoprotective as well as analgesic activities. [1][2][3][4][5][6][7][8][9][10][11] Embelia ribes, besides being a good antioxidant, anti-bacterial and analgesic like Cyperus rotundus, has been shown to possess anti-anxiety, anti-cancer, anti-fertility activities with neuroprotective and cardioprotective action. 12 , while Plumbago zeylanica is reported to be a potent anti-oxidant with anti-atherogenic, antifungal, antitumor, hepatoprotective, neuroprotective and cardiotonic activity.…”

Section: Introductionmentioning

confidence: 99%

In Vitro Free Radical Scavenging Potential of Trimad (A Polyherbal Formulation)

Salunke¹,

Giramkar²,

Bhalerao³

2017

Int. J. Res. Ayurveda Pharm.

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The objective of the present study was to evaluate aqueous extract of Trimad for its in vitro antioxidant activity. A battery of in vitro biochemical tests such as total phenol content, ferric reducing power, ABTS [2, 2 azino-bis (3-ethylbenzothiazoline-6-sulphonic acid)] scavenging activity and Lipid peroxidation inhibitory activity was used. The total phenol content of Trimad was found to be 279.5 mg/g dry mass. In case of DPPH scavenging activity, Trimad was found to be more potent than ascorbic acid at all given concentrations. It also showed significant ferric reducing potential (0.110% at 20μg/ml) and ABTS scavenging activity (31% at 80μg/ml). Trimad however showed very minimal (4.754% at 100μg/ml) lipid peroxidation activity. Our findings indicate promising antioxidant activity of Trimad extract however it needs further attention for its effective use in both modern and traditional system of medicines

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Evaluation of the Antioxidant activity of the roots and Rhizomes ofCyperus rotundusL.

Cited by 40 publications

References 0 publications

Antidiabetic and Antioxidant Potential of GancidinW from Streptomyces Paradoxus VITALK03

Antidiabetic and Antioxidant Potential of GancidinW from Streptomyces Paradoxus VITALK03

In Vitro Regulation of Non-enzymatic Antioxidant Efficiency of Momordica dioica Roxb by Elicitation and Salt Stress

In Vitro Free Radical Scavenging Potential of Trimad (A Polyherbal Formulation)

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