Evaluation of the Reflux Symptom Index and the Endolaryngeal Findings Scale after Treatment in Individuals with Laryngopharyngeal Reflux

Abstract

Introduction Laryngopharyngeal reflux (LPR) is a prevalent condition in outpatients visiting the otorhinolaryngological clinic, with many controversies regarding its diagnosis and follow-up. Therefore, there is a need for clinical instruments that can diagnose individuals and monitor the results of their treatment. Objective To evaluate the applicability of the scores translated and adapted to Brazilian Portuguese: Reflux Symptom Index (RSI) and Endolaryngeal Reflux Findings Scale (ERFS), as instruments for post-treatment follow-up of LPR. Method A total of 35 individuals with atypical symptoms of gastroesophageal reflux disease and with an objective diagnosis of LPR, confirmed by high digestive endoscopy and 24-hour esophageal pH-metry dual probe test were submitted to the RSI and ERFS questionnaires, used in the pre- and post-treatment of 90 days with a Proton Pump Inhibitor. Result The evaluation of RSI and ERFS in the pre- and post-treatment showed a reduction in the results of the two scores, with a higher drop in the RSI (p < 0.001) than in the ERFS (p = 0.014). Although there was an improvement in the values in 23.9% of the individuals in the ERFS, there was no change in the category (p = 0.057), different from the RSI (p < 0.001), where there was a 67.4% improvement in values, as well as change in category (score went from positive to negative). There was a correlation between RSI and ERFS, moderate in the pretreatment and strong in the post-treatment. Conclusion The RSI and ERFS scores, when translated and adapted for Brazilian Portuguese and applied simultaneously, can be considered a good tool for post-treatment LPR follow-up.

Improvement of the Life Quality for Laryngopharyngeal Reflux Patients After Receiving Proton Pump Inhibitor (Ppi) Therapy at the Ent-Kl Polyclinic of Uki Hospital January 2021 - February 2021

“…Another study conducted by Lee et al Also stated a significant change in the RSI score after receiving PPI therapy for four weeks, from 13.15 with a standard deviation of 8.68 to 10.03 with a standard deviation of 8.97 (p. <0.01) Lee et al (2014). It is also in line with a study conducted by Silva et al, which showed a significant decrease in the RSI score after PPI administration, from the mean initial score before treatment of 16.0 to 10.5 after being given therapy (p <0.001) Álvaro Siqueira Silva et al (2021).…”

“…It is consistent with Somashekara & Kamath's research in 2015, which showed that LPR incidence was more common in women (56.66%) than men (43.33%) Somashekara and Kamath (2015). Other studies also show that LPR is dominated by women, namely 85.7%, while men are only 14.3% Álvaro Siqueira Silva et al (2021). Another research conducted at RSUP DR. M. Djamil Padang for the period 2017 showed that LPR patients were found in 66.27% women and only 33.73% in men with a ratio of male to female ratio of 1: 2 Sa&apos;an and N (2017).…”

Laryngopharyngeal Reflux Disease: Outcome of Patients After Treatment in Otolaryngology Clinics

“…The RFS and RSI showed significant improvement after initiation of treatment at the 4th week and 12th week, respectively, and the p-value was found to be significant (< 0.01). The study results were found comparable with Belafsky et al [9][10] and Silva et al [12]. Belafsky continued treatment for a period of six months, whereas, in our study, treatment was given for three months.…”

“…In our study, we found the mean age of patients who were diagnosed with LPR was 41.8 (SD=±10.1) years, which was comparable with studies in the published literature [ 12 ]. While most of the patients were female, i.e.…”

Analysis of Helicobacter pylori in Saliva of Patients with Laryngopharyngeal Reflux and Non-Laryngopharyngeal Reflux

“…Another study conducted by Silva et al found a higher average age in LPR patients, which was 47.2 years, from the age of 29 years to 73 years. All of these studies shown that the average age of LPR patients globally is above 40 years [12], [13].…”