Evidence on the Health Benefits of Supplemental Propolis

Abstract

Propolis is a honey-related product with reported health benefits such as improved immunity, lowered blood pressure, treated allergies and skin conditions. A literature review and narrative synthesis were conducted to investigate the evidence on the reported health benefits and future direction of propolis products. Using a predefined search strategy we searched Medline (OvidSP), Embase and Central for quantitative and qualitative studies (1990–2018). Citation, reference, hand searches and expert consultation were also undertaken. Studies of randomised control trials and observational data on humans with health-related outcomes were included. Collected data were entered into NVivo software (Version 12, QRS International) and analysed using a thematic framework and a narrative synthesis of emergent themes. A total of 63 publications were discussed. The majority were cell-based and animal studies, with a few key human trials conducted. There is significant promise for propolis as an effective antioxidant and anti-inflammatory agent with particular promise in cardiometabolic health.

Effect of Chinese Propolis as an Intracanal Medicament on Post-Operative Endodontic Pain: A Double-Blind Randomized Controlled Trial

“…Placing intracanal medicaments is one of the most conservative methods for reducing the microbial load and incidence of interappointment pain. In vitro studies regarding the anti-microbial [16,27,28], anti-inflammatory [29,30], and biocompatibility [31] properties along with other benefits of propolis due to its antioxidant effects have shown immense potential [32]. However, the effect of propolis on post-instrumentation pain was unknown.…”

Natural Compounds: A Dynamic Field of Applications

“…Propolis and honey are valuable natural products with several health applications already described in the literature [69,70]. However, the properties and chemical composition of these natural products significantly depend on several factors such as the plant species used in their production [71].…”

Fonksi̇yonel Bi̇r Ürün Olan Propoli̇si̇n Sağlik Üzeri̇ne Etki̇si̇

“…2013. Genel olarak kullanımının güvenli olduğu bildirilen propolisin çeşitli araştırmalarda belirlenen toksik etkileri nedeniyle kullanımında tıbbi tavsiye alması gerekmektedir (Braakhuis 2019).…”