Extraction and purification of solanesol from tobacco(I). Extraction and silica gel column chromatography separation of solanesol

Tang, De-Song; Zhang, Lin; Chen, Huan-Lin; Liang, Yue-Rong; Lu, Jian-Liang; Liang, Hu; Zheng, Xin-Qiang

doi:10.1016/j.seppur.2007.01.040

Cited by 45 publications

(16 citation statements)

References 16 publications

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“…[1] Due to its special properties, the separation and purification of SSO has attracted extensively attention all over the world. [2][3][4][5] On the basis of structure predetermination, specific recognition, and extensive practicability, [6] molecular imprinting technique has been used in membrane separation, solid phase extraction and chromatographic separation, [7][8][9] and molecular imprinted polymers (MIPs) have become an increasingly active field of study for the construction of new materials capable of molecular recognition. [10] Some exciting results were obtained using SSO-MIP.…”

Section: Introductionmentioning

confidence: 99%

Preparation and adsorption property of solanesol molecular imprinted polymers

Long

Chen

Liu

et al. 2015

Designed Monomers and Polymers

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Molecular imprinted polymers of solanesol (SSO-MIPs) were synthesized through solution polymerization using solanesol (SSO) as the template molecule, N-vinylpyrrolidone (NVP) and acrylic acid (AA) as functional monomers, ethyleneglycol dimethacrylate (EGDMA) as cross-linker and azodiisobutyronitrile (AIBN) as initiator. Focused on the adsorption capacity and separation degree of MIP-SSO to SSO from the mixture of SSO and Triacontanol (TAL), the effects of the monomers, cross-linker and initiators on them were investigated and optimized. Finally, the structure of MIP-SSO prepared under the optimal conditions was characterized using Fourier transform infrared and scanning electron microscope. To obtain the more objective results, non-imprinted molecular polymers (NMIPs) prepared under the same condition was also characterized as contrast.

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Section: Introductionmentioning

confidence: 99%

Preparation and adsorption property of solanesol molecular imprinted polymers

Long

Chen

Liu

et al. 2015

Designed Monomers and Polymers

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“…Furthermore, the traditional solvent extraction methods used more than 10-fold solvent [14,26] and extracted the materials for two or more times [12,27] in microwave-assisted [14,15] or ultrasoundassisted [11,26] maceration extractions, or extracted the materials at high temperatures in refluxing extraction [12,27]. Our work presented here combined the extraction of nicotine and solanesol, the saponification or hydrolysis of solanesol esters and the release of bound form nicotine into one step using a carefully designed alkali extraction solvent.…”

Section: Purification Of Solanesolmentioning

confidence: 99%

“…Tobacco is the main natural source for the isolation of nicotine and solanesol. Many protocols have been published for the extraction of nicotine and solanesol from tobacco leaves and wastes, which includes heat reflux extraction [11], solid phase extraction [12], ultrasound-assisted [11,13] or microwave-assisted extractions [14,15], and supercritical fluid extraction [16]. However, these reports are mainly for the extraction of a single compound.…”

Section: Introductionmentioning

confidence: 99%

Simultaneous extraction of nicotine and solanesol from waste tobacco materials by the column chromatographic extraction method and their separation and purification

Wang

et al. 2015

Separation and Purification Technology

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“…Besides, silica gel is very easily available commercially in many different forms. [24][25][26] In addition, silica gel column chromatography depends on the silica gel activity and on the polarity of the compounds. 26) However, in our previous research (unpublished) we did not obtain a good separation of DHAA in a large scale using silica gel alone as the adsorbent.…”

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confidence: 99%

Preparative Separation of High-Purity Dihydroartemisinic Acid from Artemisinin Production Waste by Combined Chromatography

Liu¹,

Ferreira

Tian³

et al. 2018

CHEMICAL & PHARMACEUTICAL BULLETIN

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In order to make full use of artemisinin production waste and thus to reduce the production cost of artemisinin, we developed an efficient and scalable method to isolate high-purity dihydroartemisinic acid from artemisinin production waste by combining anion-exchange resin with silica-gel column chromatography. The adsorption and desorption characteristics of dihydroartemisinic acid on 10 types of anion-exchange resin were investigated, and the results showed that the 717 anion-exchange resin exhibited the highest capacity of adsorption and desorption to dihydroartemisinic acid. Adsorption isotherms were established for the 717 anion-exchange resin and they fitted well with both Langmuir and Freundlich model. Dynamic adsorption and desorption properties of 717 anion-exchange resin were characterized to optimize the chromatographic conditions. Subsequently, the silica-gel column chromatography was performed and dihydroartemisinic acid with a purity of up to 98% (w/w) was obtained. Finally, the scale-up experiments validated the preparative separation of high-purity dihydroartemisinic acid from industrial waste developed in the present work. This work presented for the first time an isolation of dihydroartemisinic acid with a purity of 98% from Artemisia annua (A. annua) by-product, which adds more value to this crop and has the potential to lower the prices of anti-malarial drugs.

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Extraction and purification of solanesol from tobacco(I). Extraction and silica gel column chromatography separation of solanesol

Cited by 45 publications

References 16 publications

Preparation and adsorption property of solanesol molecular imprinted polymers

Preparation and adsorption property of solanesol molecular imprinted polymers

Simultaneous extraction of nicotine and solanesol from waste tobacco materials by the column chromatographic extraction method and their separation and purification

Preparative Separation of High-Purity Dihydroartemisinic Acid from Artemisinin Production Waste by Combined Chromatography

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