Fabrication of PDMS multi-layer microstructure: The electroosmosis mechanism in fluidics for life sciences

The effect of exposure time and development time on photoresist thin film in Micro/Nano structure formation

“…For technology of device with nano size, misalignment must be controlled to operate within tolerable error limit or total elimination of misalignment but in most cases, such precision needs automatic alignment systems. This is a very challenging, since not every researcher in this field can afford such device but with careful design procedure, researchers can eliminate error dimension and yet maintain low cost of fabrication [11][12][13][14]. Hence, in this study, we demonstrated a good designed and fabrication method for realization of a minimum possible nano sizes wires, we have carried out the design of four wires of size 1nm, 2nm, 3nm, and 5nm which we were successfully established not only the design and fabrication parameters but we went further to establish some critical parameters such as resist coating, soft bake, exposure time and intensity, and development time used in realization of nano structures.…”

Chrome Mask Design for Microfluidic Fabrication

“…Eventually, various microfluidic fabrication technique has been develop however the fabrication using SU-8 as master template and pouring PDMS on master is well known simple and cost effective method [4]. SU-8 material are low cost negative resists which used to coated on silicon to form master template [5]. Conventional photolithography prosess which consists of three major step; 1) Coating photoresists on substrate, 2) Selectively exposing to UV radiation using mask, 3) Removing the region that remain soluble [6].…”

Design and Fabrication of PDMS Microchamber for Fast Reaction Assays in Biosensing Application

“…The sensing element was successfully surface modified and tested on real biomedical clinical sample for evaluation and validation. The integration of microfluidics with nano-electronic sensor for the implementation of complex reaction protocols Need Capillary that has no moving parts [1], is simple and easy to implement and thus is very attractive for low-cost Microfluidic devices is very important and There is a wide spread interest in micron-scale integrated bio-molecule analysis or synthesis systems which is referred to as lab-on-a-chip [1,2]. A critical to this is the ability to drive a sample through the device without both moving parts and an external actuation since at the microscale level moving parts in an active mixer are very fragile.…”

“…A critical to this is the ability to drive a sample through the device without both moving parts and an external actuation since at the microscale level moving parts in an active mixer are very fragile. Capillarity is a force that results from the interaction of cohesion of molecules of a liquid to each other and adhesion of these molecules to the surrounding material [1][2][3][4].…”