Faktor Resiko yang Berhubungan dengan Kejadian Kanker Payudara di Rumah Sakit Umum Daerah dr. H.Abdoel Moeloek Provinsi Lampung

Abstract

Risk Factor Related to Breast Cancer Incident in General Hospital dr. H. ABDUL Moeloek Lampung. Data on the incidence of breast cancer in 2014 at the Regional General Hospital dr. H. Abdul Moeloek Bandar Lampung as many as 1,347 people, while data on outpatient during 2014 as many as 3,500 people. This research uses a quantitative method with cross sectional study design. The study population of all patients who visit the hospital either outpatient care during the study period as many as 1,347 people. The sample was 99 people. The sampling technique using simple random sampling method. Data analysis was performed using chi-square and logistic regression. The results showed that there is influence of genetic factors (pvalue= 0.000), age (p-value = 0.000), early menarche (p-value= 0.001), use of contraception (pvalue= 0.012) and obesity (p-value= 0.012) on the incidence of breast cancer in the Regional General Hospital dr. H. Abdul Moeloek Bandar Lampung in 2014. The most influential factor on the incidence of breast cancer in the Regional General Hospital dr. H. Abdul Moeloek Bandar Lampung in 2014 is the age factor with OR= 12.769. Advice, respondents expected to increase their knowledge about BSE, especially with age where age >50 years is the age most susceptible to breast cancer. Results of this study are expected to be used as input and the recommendation to health institution, especially the units closest to the public health services to improve health education programs in particular about early detection of breast cancer by providing counseling to mothers to prevent and reviews with breast cancer.

Correlation between Age and Body Mass Index (BMI) with Histopathological Features of Breast Cancer Patients in RSUP Haji Adam Malik Medan

“…Obesity might activate the other molecular pathway than the estrogenic circuit, which played a role in breast cancer pathogenesis. It is also verified by research by Suryani et al [19] that a p=0.012 indicated a correlation between obesity factor and breast cancer incidence. Besides, another research obtained an OR value of 2.199, meaning that obese women had a risk of 2.199 bigger become breast cancer compared to women who were not obese [27].…”

“…Obese patients in the postmenopausal period have estrogenic production from adipose tissue, where IGF-1 and insulin are growth factors [11]. The combined effects of both will decrease normal apoptosis and continuously stimulate cell division, which can cause breast cancer [19]. This study's limitations were related to obtaining research data and not discussing the difference between patients with breast cancer and patients without breast cancer.…”

“…Further research is expected using better research design and discussing other factors that correlate with breast cancer occurrence. higher; besides, physiologically, there is a decreased organ function and endurance [19].…”

Pengetahuan Wanita Usia Subur Tentang Pencegahan Kanker Payudara

“…Menurut (Anggorowati, 2013) bahwa faktor yang berhubungan dengan kejadian kanker payudara adalah obesitas, usia melahirkan anak pertama, riwayat pemberian ASI, dan usia menarche. Bahwa ada hubungan faktor genetik, usia, menarche dini, penggunaan kontrasepsi dan obsesitas terhadap kejadian kanker payudara (Suryani et al, 2016). Faktor risiko yang paling berpengaruh terhadap kejadian kanker payudara adalah riwayat keluarga yang memiliki dibandingkan wanita yang tidak memiliki riwayat keluarga yang sedang atau pernah menderita kanker payudara (Priyatin et al, 2013).…”

Adverse Drug Reactions (ADRS) Antikanker pada Pasien Ca Mammae yang Menjalani Kemoterapi di RSUD Kota Yogyakarta

“…Sebanyak 12 pasien (29,3%) mempunyai riwayat kanker dari keluarga (riwayat dari ibu/saudara perempuan/sepupu perempuan) yang pernah mengalami ca mammae. Menurut penelitian (Suryani et al, 2016) Dalam penelitian ini sebanyak 23 pasien (56,1%) mempunyai riwayat sebagai perokok pasif (suami/anak laki/saudara serumah yang merokok). Hasil ini sejalan dengan penelitian (Metsky et al, 2017) pada pasien ca mammae menunjukkan bahwa wanita yang terkena paparan sebagai perokok pasif dalam waktu lama yaitu ≥20 tahun sebagai orang dewasa di rumah dan ≥10 tahun sebagai orang dewasa di tempat kerja akan memiliki risiko ca mammae 32% lebih tinggi dibandingkan dengan wanita yang tidak termasuk perokok pasif.…”