Fatty metamorphosis in hepatocellular carcinoma: radiologic features in 10 cases

T2‐weighted MR imaging for focal hepatic lesion detection: Supplementary value of breath‐hold imaging with half‐fourier single‐shot fast spin‐echo and multishot spin‐echo echoplanar sequences

“…Although ideally histologic proof should be obtained from all tumors by definitive surgery, lesions can otherwise be confirmed with intraoperative sonography; it is becoming more infrequent to obtain surgical proof, especially in patients with hepatocellular carcinoma because small hepatocellular carcinomas are often treated with transcatheter arterial chemoembolization or percutaneous ablation, particularly in cirrhotic patients whose functional reserve is severely impaired. Some hepatocellular carcinomas undergo fatty metamorphosis (20), and the use of fat suppression may obscure such lesions although we did not experience this in the present study. We did not include dysplastic nodules in cirrhosis, which may have a premalignant potential and can be seen as hypointense lesions with T2-weighted images, because the clinical significance of these nodules is still controversial.…”

Atypically large well-differentiated hepatocellular carcinoma with extensive fatty metamorphosis: Report of a Case

“…Some HCC include fatty tissue within the tumor (3)(4)(5). It is reported that 10 of 600 HCC cases demonstrated fat metamorphosis (6). Fatty changes are noted to be diffuse in smaller tumors within 35 mm and concentrated in lager tumors.…”

Hepatic angiomyolipoma

“…Hepatomas may contain fat and this may be seen diffusely scattered throughout the tumor or localized in small foci or as a mosaic pattern [20,25,26]. Other fat- Angiography is usually used to define the vascular anatomy of a tumor prior to resection.…”