The article is devoted to the question of the influence of various agro-technological methods on the development of diseases, pests, as well as on the lodging of spring wheat. Over the years of research (2019–2020) on spring wheat crops, the effect of calculated doses of fertilizers at different rates of sowing seeds on plant damage by latent pests and leaf rust damage, as well as the resistance of spring wheat plants to lodging was studied. On the basis of the results obtained, it was possible to establish that at strongly reduced seeding rates, regardless of the nutritional background, the number of damaged plants by the fruit fly, as well as damage by leaf rust, increased sharply. At the same time, excessive thickening of crops did not contribute to a significant further decrease in damage and susceptibility, as well as to lodging of plants.