Fine structure study on low concentration zinc substituted hydroxyapatite nanoparticles

Hu, Wang; Ma, Jun; Wang, Jianglin; Zhang, Shengmin

doi:10.1016/j.msec.2012.07.014

Cited by 73 publications

(38 citation statements)

References 35 publications

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“…The width and the length of the rod-like particles are approximately 50-200 nm and 150-300 nm, respectively, and an aspect ratio is approximately 1.8. This is consistent with the work of Hu et al where rod-like Zn-doped HA nanoparticles were observed [9]. Similar result was also found in …”

Section: Phase and Morphology Of The Doped And Undoped Hydroxyapatitesupporting

confidence: 93%

Preparation of strontium- and/or zinc-doped hydroxyapatite nanoparticles and their polycaprolactone composite fibrous scaffolds

Pantasri

Seet

Suwanna

2017

J. Phys.: Conf. Ser.

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Section: Phase and Morphology Of The Doped And Undoped Hydroxyapatitesupporting

confidence: 93%

Preparation of strontium- and/or zinc-doped hydroxyapatite nanoparticles and their polycaprolactone composite fibrous scaffolds

Pantasri

Seet

Suwanna

2017

J. Phys.: Conf. Ser.

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“…The shift of the XRD peaks, with respect to the Cu-free HAP (JCPDS No. 09-0432), served as evidence of Cu substitution in obtained coatings [28]. The unit cell of HAP contains 10 Ca 2?…”

Section: Resultsmentioning

confidence: 96%

Antibacterial efficacy, corrosion resistance, and cytotoxicity studies of copper-substituted carbonated hydroxyapatite coating on titanium substrate

et al. 2014

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This work elucidated the antibacterial efficacy, corrosion resistance, and cytotoxicity of electroplated copper-substituted hydroxyapatite (CuHAP) coating on titanium (Ti). The fabricated CuHAP coatings were characterized by scanning electron microscopy, energydispersive X-ray analysis spectroscopy, Fourier transform infrared spectroscopy, and X-ray diffraction studies. The CuHAP coating had needle-like apatite crystals, the doping of Cu 2? into HAP reduced porosity, and the coating became denser. The CuHAP crystals were carbonated with a few of Cu 2? incorporation (about 0.80 wt%). The Cu 2? ions were homogenously deposited into HAP films. Potentiodynamic polarisation test revealed that the CuHAP coating provided good barrier characteristics and achieved superior corrosion protection for Ti substrates. The in vitro antibacterial activity of asprepared CuHAP coating was evaluated against Escherichia coli and was found to be effectively high against bacterial colonization. Bioactivity test conducted by soaking the coatings in simulated body fluid demonstrated that CuHAP coating can quickly induce bone-like apatite nucleation and growth. In vitro biocompatibility tests, MTT, were employed to assess the cytotoxicity of Cu-HAP coating with osteoblast-like MC3T3-E1 cells. The obtained HAP coating doped with a low content of Cu 2? exhibited good cytocompatibility and had no toxicity toward MC3T3-E1.

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“…Zn 2 þ doped HAs were synthesized to investigate their antimicrobial characteristics, microstructure, sintering behavior, and in-vivo responses [17][18][19][20][21]. It was shown that Zn incorporation into implants promotes bone formation around the implant and decreases the inflammatory response [16,22].…”

Section: Introductionmentioning

confidence: 99%

Co-doping of hydroxyapatite with zinc and fluoride improves mechanical and biological properties of hydroxyapatite

Uysal

Severcan

Tezcaner

et al. 2014

Progress in Natural Science: Materials International

107

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Hydroxyapatite (HA) co-doped with Zn 2 þ and F À ions was synthesized by precipitation method for the first time in this study. FTIR spectroscopy revealed Zn 2 þ and F À ions incorporation into HA structure. Co-doping of Zn 2 þ and F À ions decreased unit cell volume of HA and decreased grain sizes. Zn 2 þ or 5 mol% F À addition into HA significantly improved its density. Microhardness was increased with Zn 2 þ addition and further increase was detected with F À co-doping. Zn 2 þ and F À co-doped samples had higher fracture toughness than pure HA. Zn 2 þ incorporation to the structure resulted in an increase in cell proliferation and ALP activity of cells, and further increase was observed with 1 mol% F À addition. With superior mechanical properties and biological response 2Zn1F is a good candidate for biomedical applications.

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Fine structure study on low concentration zinc substituted hydroxyapatite nanoparticles

Cited by 73 publications

References 35 publications

Preparation of strontium- and/or zinc-doped hydroxyapatite nanoparticles and their polycaprolactone composite fibrous scaffolds

Preparation of strontium- and/or zinc-doped hydroxyapatite nanoparticles and their polycaprolactone composite fibrous scaffolds

Antibacterial efficacy, corrosion resistance, and cytotoxicity studies of copper-substituted carbonated hydroxyapatite coating on titanium substrate

Co-doping of hydroxyapatite with zinc and fluoride improves mechanical and biological properties of hydroxyapatite

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