Formation of hydroxyl radicals and Co3+ in the reaction of Co2+-EDTA with hydrogen peroxide. catalytic effect of Fe3+

Eberhardt, Manfred K.; Santos, Cynthia Barbosa Albuquerque dos; Soto, Margie Ann

doi:10.1016/0304-4165(93)90084-l

Cited by 36 publications

(22 citation statements)

References 14 publications

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“…22,23 The reaction mixture contained 1.9 mM deoxyribose, 0.15 mM indoline derivative dissolved in DMSO or 2.2M DMSO as a control, 0.38 mM CoCl 2 , and 3.8 mM H 2 O 2 . The reactions were carried out in phosphate buffer, pH 8.0 (66 mM KH 2 PO 4 , 66 mM Na 2 HPO 4 ).…”

Section: Methodsmentioning

confidence: 99%

Scavenging of reactive oxygen species by novel indolin‐2‐one and indoline‐2‐thione derivatives

Aboul‐Enein¹,

Kładna

Kruk

et al. 2005

Biopolymers

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The antioxidant behavior of a series of new synthesized substituted indoline-2-ones and indolin-2-thiones was investigated in this study using an oxygen radical absorbance capacity assay (ORAC(ROO*-) and 2,2'-azobis(2-amidino-propane) dihydrochloride (AAPH) as the radical generator; system generating superoxide anion radical, O2*- (18-crown-6/KO(2)/DMSO), and the Fenton-like reaction [Co(II) + H(2)O(2) --> Co(III) + HO(*) + HO(-)]. Measurements were done using fluorescence, chemiluminescence methods, and a deoxyribose assay based on the spectrophotometry method, respectively. The results obtained indicated that the examined indoline derivatives had effective activities as radical scavengers and may be considered as an effective source for combating oxidative damage.

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Section: Methodsmentioning

confidence: 99%

Scavenging of reactive oxygen species by novel indolin‐2‐one and indoline‐2‐thione derivatives

Aboul‐Enein¹,

Kładna

Kruk

et al. 2005

Biopolymers

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“…As reported previously, the reaction between Co(II) and H 2 O 2 produces HO radicals in aqueous solution as follows 17 :…”

Section: Resultsmentioning

confidence: 83%

Effect of psoralens on Fenton‐like reaction generating reactive oxygen species

et al. 2002

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Psoralens (psoralen, khellin, and visnagin) in 1 mM doses were shown to enhance the generation of reactive oxygen species, such as the hydroxyl radical (HO ⅐ ), the superoxide anion radical (O 2 Ϫ • ), and singlet oxygen ( 1 O 2 ), from the system generating chemiluminescence (CL), as well as free radicals in the absence of light. The system that generated CL was made up of CoCl 2 and H 2 O 2 . Incubation of psoralens in 0.2 mM doses with the generating system showed that only 8-methoxypsoralen and khellin have antioxidative effects. Antioxidative effects were also observed in the case of visnagin but in low concentration (0.05 mM). High doses of psoralens (1 mM) showed prooxidative effects. Measurements were done using a deoxyribose assay, the CL method, and spin-trapping with 5,5-dimethyl-1-pyrroline-N-oxide and 2,2,6,6-tetramethylpiperidine combined with electron spin resonance spectroscopy and spectrophotometry methods.

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“…As has been reported [10] the reaction between Co(II) and H2O2 in the presence of EDTA produces HO radicals as follows:…”

Section: Resultsmentioning

confidence: 92%

Antioxidant action of severalβ‐adrenergic blockers and related compounds

Aboul‐Enein¹,

Kruk

Lichszteld

1999

Toxicological & Environmental Chemistry

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Formation of hydroxyl radicals and Co3+ in the reaction of Co2+-EDTA with hydrogen peroxide. catalytic effect of Fe3+

Cited by 36 publications

References 14 publications

Scavenging of reactive oxygen species by novel indolin‐2‐one and indoline‐2‐thione derivatives

Scavenging of reactive oxygen species by novel indolin‐2‐one and indoline‐2‐thione derivatives

Effect of psoralens on Fenton‐like reaction generating reactive oxygen species

Antioxidant action of severalβ‐adrenergic blockers and related compounds

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