FORMULASI KRIM EKSTRAK ETANOL DAUN KIRINYUH (Eupatorium odoratum L.) SEBAGAI ANTIINFLAMASI

Yenti, Revi; Afrianti, Ria; P, Agustina Endang

doi:10.36434/scientia.v4i1.72

Cited by 11 publications

(17 citation statements)

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“…Flavonoid compounds contain phenol compounds which have the ability to inhibit the formation of pathogenic fungal conidia, denature proteins and damage cell membranes so that it can be said that flavonoid compounds can act as antibacterial agents. According to Yenti (2011) [14]. flavonoids can inhibit bacterial growth by damaging the permeability of bacterial cell walls, microsomes and lysosomes as a result of interactions between flavonoids with bacterial DNA and also being able to release energy transduction to the bacterial cytoplasmic membrane and inhibit bacterial motility.…”

Section: Resultsmentioning

confidence: 99%

Bioactivity of Torch Ginger Umbut Extract (Etlingera elatior) Against Heal Wounds of Mice (Mus musculus)

Efendi

Sumarmin

Fadil

2020

Eksakta

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Torch ginger has a wide range of good antimicrobial, antioxidant, anticancer, larvicidal and repellent activities. Active compounds in Torch ginger that affect pharmacological activities are phenols, polyphenols, flavonoids, and terpenoids. Based on these ingredients Torch ginger can be used to heal wounds. This study aims to observe the effect of Torch ginger Umbut extract on wound healing in mice. This study hopes to add information about the effect of Torch ginger umbut extract on the healing of cuts in mice so that it can be another alternative for wound healing and can be a reference for other researchers. This study used a completely randomized design with 5 treatments and 3 replications. Tests carried out on adult male mice. The results showed that the optimal wound healing in P2 is treatment with 10% Torch ginger umbut extract which requires a range of wound healing 7-8 days. Based on these results, Torch ginger umbut extract can heal wounds.

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Section: Resultsmentioning

confidence: 99%

Bioactivity of Torch Ginger Umbut Extract (Etlingera elatior) Against Heal Wounds of Mice (Mus musculus)

Efendi

Sumarmin

Fadil

2020

Eksakta

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“…Adanya dampak negatif tersebut menyebabkan timbulnya pergeseran perspektif dari penggunaan bahan kimia ke bahan yang bersifat alami. Hingga saat ini, banyak riset telah dilakukan untuk menemukan ekstrak bahan alami yang dapat menstimulasi dan meningkatkan regenerasi penyembuhan luka (Amaliya, Soemantri, & Utami, 2013;Wijaya, Citraningtyas, & Wehantouw, 2014;Yanti, Afrianti, & Afriani, 2011). Penggunaan ekstrak bahan alami umumnya merupakan kebiasaan yang dilakukan oleh masyarakat tradisional secara turun-temurun.…”

Section: Pendahuluanunclassified

Daun Mangga (Mangifera indica L): Potensi Baru Penyembuh Luka Sayat

Risa¹,

Pantiwati²,

Mahmudati

et al. 2018

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The use of antiseptics in wounds can cause long-term side effects. This study aims to determine the potential of mango leaves (Mangifera indica L) as a natural ingredient for healing wounds. This true experimental research used six treatment groups. This study used a completely randomized design of four repetitions using 24 samples of white rats (Rattus norvegicus) taken randomly. The results of the Anova statistical test showed that there was a difference in the effect of giving mango leaf extract to incisive wound healing. The results showed that a concentration of 20% showed a faster recovery time of 7.25 days with an average wound closure of 4.02 mm. This indicates that the extract of mango leaves has the potential to be used as a healing wound for the incision.

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“…Pada penelitian sebelumnya telah dilakukan pengujian terhadap aktivitas antimikroba ekstrak daun kirinyuh, hasilnya menunjukkan positif terhadap bakteri Bacillus subtillis, Staphylococcus aureus dan Salmonella typhimurium (Vital & Rivera, 2009), juga telah dilakukan pengujian terhadap ekstrak etanol daun kirinyuh untuk pengobatan luka pada mencit jantan, kontrol dan pembanding, hasilnya menunjukkan bahwa ekstrak etanol daun kirinyuh memberikan efek penyembuhan luka yang lebih cepat (Yenti et al, 2011).…”

Section: Pendahuluanunclassified

TOKSISITAS AKUT EKSTRAK ETANOL DAUN KIRINYUH (CHROMOLAENA ODORATA (L) R.M. KING & H. ROB) PADA MENCIT PUTIH JANTAN

Nirwanto¹,

Ariadi²,

Arifin³

2018

MHSJ

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The acute toxicity of ethanol extracts from Kirinyuh (Chromolaena odorata (L) R.M.King & H. Rob) leaves to white mice males has been done. Parameters toxicity observed were LD50and delayed toxic effects for 14 days of observation including changes in weight, volume of waterconsumption, and relative weight of the organs like heart, liver, kidneys, stomach and lungs. Theethanol extract of Chromolaena odorata (L) R.M King & H. Rob leaves orally at a dose of 4 g/kgBB,8 g/kgBB and 16 g/kgBB, showed that was categorized practically non-toxic (LD50> 15 g/kgBB).Delayed toxic effects are seen from the significant differences in body weight, the volume of water,relative organ weight of lung and stomach (P<0.05). There were no significant differences in therelative organ weight of the heart, liver and kidneys (P<0.05).

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FORMULASI KRIM EKSTRAK ETANOL DAUN KIRINYUH (Eupatorium odoratum L.) SEBAGAI ANTIINFLAMASI

Cited by 11 publications

References 0 publications

Bioactivity of Torch Ginger Umbut Extract (Etlingera elatior) Against Heal Wounds of Mice (Mus musculus)

Bioactivity of Torch Ginger Umbut Extract (Etlingera elatior) Against Heal Wounds of Mice (Mus musculus)

Daun Mangga (Mangifera indica L): Potensi Baru Penyembuh Luka Sayat

TOKSISITAS AKUT EKSTRAK ETANOL DAUN KIRINYUH (CHROMOLAENA ODORATA (L) R.M. KING & H. ROB) PADA MENCIT PUTIH JANTAN

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