Formulation and Evaluation of Herbal Anti-bacterial gel containing Ethanolic extracts of <i>Rosa indica</i> and <i>Tagetes minuta</i>

Mandadi, Sandhya; Prathyusha, K.; Rani, Mary Shobha; Goud, K. Sridivya; Reddy, Kalivemula Divya; Swamy, Mahadeswara

doi:10.5958/0975-4377.2020.00007.5

Rese. Jour. Pharmaceut. Dosag. Form. and Technol.

2020

DOI: 10.5958/0975-4377.2020.00007.5

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Formulation and Evaluation of Herbal Anti-bacterial gel containing Ethanolic extracts of Rosa indica and Tagetes minuta

Sandhya Mandadi¹,

K. Prathyusha²,

Mary Shobha Rani³

et al.

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Cited by 5 publications

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Phytochemical screening and antioxidant activity of methanolic extracts of 53 antimalarial plants from Bagira in Eastern DR Congo

Chiribagula¹,

Bakari²,

Ndjolo³

et al. 2020

GSC Biol. and Pharm. Sci.

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A previous study inventoried 53 plants used in traditional medicine in Bagira in Eastern Democratic Republic of Congo (DRC) in the management of malaria. During malaria disease, oxidative stress is responsible for the worsening of the patient's condition. This study aims to identify phytochemical groups and to evaluate antioxidant activity of 53 plants used in traditional medicine in Bagira to treat malaria. The phytochemical screening was carried out by conventional reactions in solution and antioxidant activity used in vitro method with 1,1-diphenyl-2-picrylhydrazyl radical (DPPH). Chemical screening has identified secondary metabolites with both antimalarial and antioxidant potential such as coumarins, steroids, saponins, tannins and terpenoids in more than 70% of plants. Antioxidant screening revealed for the first-time antioxidant activity of 18 plants, among which Dalbergia katangensis, Dialium angolense and Solanecio cydoniifolius with IC50 ≤ 1.6 µg / mL having the highest activities. This study shows that among plants used as antimalarial in Bagira several possess antioxidant power and contain many of groups presumed to be both antioxidant and antimalarial. This suggests that further studies continue to isolate compounds responsible for the proven activity.

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Phytochemical screening and antioxidant activity of methanolic extracts of 53 antimalarial plants from Bagira in Eastern DR Congo

Chiribagula¹,

Bakari²,

Ndjolo³

et al. 2020

GSC Biol. and Pharm. Sci.

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Hair Growth-Promoting Activity of Hair Tonic containing Delipidated Ethanol Extract of Capsicum frutescens L. Leaves on Male Rabbit (Oryctolagus cuniculus)

Tendri Adjeng,

Puspita Sarry,

Muhammad Ali

et al. 2023

RJPT

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Background: One of the common features of unhealthy hair is abnormal hair loss which can lead to alopecia (baldness). Capsicum frutescens L.leaves contain saponins to increase blood flow to hair follicles and flavonoids that inhibit free radicals that cause hair loss.Hairtonic is a cosmetic product that deals with hair problems because it is easy to apply and not sticky. Objective: to formulate Hair tonic from delipidated ethanol extract of Capsicum frutescens L. leaves and to observe its hair growth-promoting effectivenesson male rabbits (Oryctolagus cuniculus). Methods: Capsicum frutescens L. leaves were extracted with ethanolby using maceration method,delipidation extract was obtained by using liquid-liquid separation technique with n-hexane as nonpolar phase, hair tonic formulations with 5%, 10% and 20% were prepared by using dissolving and stirring without heating. Results: Hair Tonic were light to dark brown, pH range was 4.5 - 5.9; Averagehair growth for 3 weeks of normal control was 6.88±0.50; negative control was 7.59±0.94; Positive control was 34.54±0.93; Hair Tonic with delipidated ethanol extract at 5%, 10% and 20%, respectively, were 18.28±0.74; 24.53±0.88; and 33.33±0.86. Conclusion: Hair Tonic with delipidated ethanol extract of Capsicum frutescens L. at 5%, 10% and 20% has potential for hair-promoting growth.Hair Tonic with delipidated ethanol extract of Capsicum frutescens L. at 5%, 10% and 20% has potential for hair-promoting growth when compared to placebo (Negative control) and Normal control. With concentration of 20%, the formulation of Hair Tonic Delipidated Ethanol Extract of Capsicum frutescens L. Leaves has hair growth-promoting activity roughly equivalent to hair tonic containing 2% Minoxidil (Positive control).

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Efficacy of Spermococe Hispida Oil preparation against Scalp Yeast and Bacterial Infections

Sree N,

et al. 2024

RJPT

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Spermacoce hispida L (Rubiaceae) commonly called Nattai Choori in Tamil has been utilized in common folk medicine. This study conducted an extraction and antibacterial analysis of crude Spermacoce hispida seed (SHS) oil. In a Soxhlet device, the dried and powdered plant material of Spermacoce hispida was heated for extraction using methanol for 48 hours and concentrated in a rotatory evaporator. Preparation of SHS Gel was done by stirring (150 RPM) with paraffin and olive oils in equal concentrations for 5 min to obtain a homogenous transparent mixture. Methanolic extract of SHS was added to the mixture at a concentration of 0.1% w/w. The antibacterial properties of the SHS oil extract were tested against Candida albicans, E. Coli, Streptococcus aureus, and Staphylococcus aureus. Throughout the test extracts investigated for their antifungal action, fluconazole was the reference medication, whereas ciprofloxacin was employed for the antibacterial experiments. The findings demonstrated that the SHS oil had significantly higher effectiveness against the investigated bacterial and fungal species. Thus SHS gel can be better product for antibacterial treatment and anti-fungal treatment against candida albicans and can also be incorporated in the preparation of any other novel antifungal formulation for treatment of scalp yeast infections.

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Formulation and Evaluation of Herbal Anti-bacterial gel containing Ethanolic extracts of Rosa indica and Tagetes minuta

Cited by 5 publications

References 0 publications

Phytochemical screening and antioxidant activity of methanolic extracts of 53 antimalarial plants from Bagira in Eastern DR Congo

Phytochemical screening and antioxidant activity of methanolic extracts of 53 antimalarial plants from Bagira in Eastern DR Congo

Hair Growth-Promoting Activity of Hair Tonic containing Delipidated Ethanol Extract of Capsicum frutescens L. Leaves on Male Rabbit (Oryctolagus cuniculus)

Efficacy of Spermococe Hispida Oil preparation against Scalp Yeast and Bacterial Infections

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