Frequency Analysis of Evoked Otoacoustic Emissions in Meniere's Disease

Kubo, Takeshi; Sakashita, Tetsushi; Kusuki, Makoto; Nakai, Yousuke

doi:10.3109/00016489509121923

Cited by 12 publications

(8 citation statements)

References 12 publications

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“…Other reports tend to concur with this negative view. Kubo et al (1995) reported that after glycerol administration, the OAE spectral components presenting the largest energy tended to be found at higher frequencies, but this happened only in a few ears. Magliulo et al (2001) reported highly variable results with little or no change either in DPOAEs or pure-tone thresholds in a sizeable percentage of glycerol-treated ears.…”

Section: Discussionmentioning

confidence: 94%

Effects of glycerol intake and body tilt on otoacoustic emissions reflect labyrinthine pressure changes in Menière’s disease

2009

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Section: Discussionmentioning

confidence: 94%

Effects of glycerol intake and body tilt on otoacoustic emissions reflect labyrinthine pressure changes in Menière’s disease

2009

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“…TEOAE were also observed to be altered in the glycerol test. Kubo et al [20] noted that endolymphatic hydrops decompression resulted in dominating TEOAE otoemission shift toward higher frequencies.…”

Section: Discussionmentioning

confidence: 99%

Dynamics of pure tone audiometry and DPOAE changes induced by glycerol in Meniere’s disease

Jablonka-Strom

Pośpiech

Zatoński

et al. 2012

Eur Arch Otorhinolaryngol

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The purpose of this study is to follow up the dynamics of pure tone threshold and DPOAE amplitude changes induced by glycerol with reference to its activity in the inner ear. Selection was made among 38 patients with Meniere’s disease for those having positive glycerol test. Pure-tone audiometry and DP-gram were performed in four series: as an initial examination before glycerol intake, 1, 2 and 3 h after. Audiometric changes formed distinct biphasal pattern at all frequencies between 250 and 4,000 Hz. The most dynamic pure tone threshold decrease occurred during the first hour. Between the first and second hour after glycerol ingestion there was a phase of no significant hearing changes. Further pure tone threshold decrease went on within the third hour reaching its top. Observing DPOAE changes, the highest DP amplitude growth occurred after the second and the third hour at DP-gram frequencies 2, 3 and 4 kHz. The fastest DP-amplitude increase was registered as well during the first hour after glycerol ingestion. In 11 persons with both audiometry and DPOAE positive glycerol test, parallel dynamics in the course of the glycerol test was observed. Biphasal glycerol test dynamics suggests the possibility of two mechanisms of glycerol activity in the inner ear.

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“…9 These results are supported by more recent findings. [11][12][13] Another potential application of OAE measurement is to augment glycerol testing in the diagnosis of Ménière's disease. An improvement in hearing upon glycerol administration is considered a positive finding for hydrops, but behavioral testing is OAEs have been found to reflect effects of glycerol on hydrops, typically increased output.…”

Section: Clinical Observationsmentioning

confidence: 99%

“…An improvement in hearing upon glycerol administration is considered a positive finding for hydrops, but behavioral testing is OAEs have been found to reflect effects of glycerol on hydrops, typically increased output. 11,13,14 Another intriguing issue is the prevalence of spontaneous OAEs in cases of hydrops. SOAEs are frequently observed in cases of totally normal hearing but rarely with even small subclinical hearing losses.…”

Section: Clinical Observationsmentioning

confidence: 99%

Possible Effects of Cochlear Hydrops and Related Phenomena

Avan¹,

Durrant²,

Büki³

2001

Semin Hear

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There is some question in the literature concerning the effects of hydrops on otoacoustic emissions (OAEs), and the usefulness of OAE measurement in the differential diagnosis of Ménière's disease and related disorders remains unclear. It is reasonable to expect different effects in various cochlear pathologies, especially between those causing primarily lowfrequency (LF) versus high-frequency (HF) hearing losses, as typically associated with putative fluid mechanical lesions versus hair cell damage, respectively. We report observations on distortion product OAEs in patients with LF and combinations of LF and HF losses and discuss problems of relating DPOAE output to the LF "hydrops" audiogram. We then describe effects specifically of intralabyrinthine pressure on OAEs, a possible factor in hydrops. It is clear from results in the literature and in our own clinics and laboratories that OAEs are sensitive to intralabyrinthine static pressure. These measures may or may not accurately reflect the hydrops hearing loss. The results are thus complex, doubtlessly reflecting the complexity and dynamics of diseases such as Ménière's. On the other hand, the effect of intralabyrinthine pressure per se is predictable and can be demonstrated to be rather predictable in humans.Learning Outcomes: As a result of this activity, the reader will be able to (1) explore the range of effects of Ménière's disease or hydrops on otoacoustic emissions and (2) learn of the sensitivity of otoacoustic emissions to intralabyrinthine pressure changes.

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Frequency Analysis of Evoked Otoacoustic Emissions in Meniere's Disease

Cited by 12 publications

References 12 publications

Effects of glycerol intake and body tilt on otoacoustic emissions reflect labyrinthine pressure changes in Menière’s disease

Effects of glycerol intake and body tilt on otoacoustic emissions reflect labyrinthine pressure changes in Menière’s disease

Dynamics of pure tone audiometry and DPOAE changes induced by glycerol in Meniere’s disease

Possible Effects of Cochlear Hydrops and Related Phenomena

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