Gelatin–Chitosan composite capped gold nanoparticles: a matrix for the growth of hydroxyapatite

Sobhana, S. S. Liji; Sundaraseelan, J.; Sekar, S.; Sastry, T. P.; Mandal, Asit Baran

doi:10.1007/s11051-008-9385-0

Cited by 47 publications

(16 citation statements)

References 30 publications

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“…Silver nanoparticles were prepared using chitosan solution by modifying the procedure described earlier [26]. Briefly, to 1 mL of chitosan solution, 1 mL of aqueous Ag 2 SO 4 solution (1 × 10 −4 M) was added followed by stirring for 1 h. To this solution, 0.2 mL of 1 M NaBH 4 (dissolved in 0.3 M NaOH) was added drop wise followed by stirring till the solution attained golden brown color.…”

Section: Preparation Of Silver Nanoparticles Using Chitosan (Ch-agnp)mentioning

confidence: 99%

Preparation, characterization and evaluation of biocomposite films containing chitosan and sago starch impregnated with silver nanoparticles

Arockianathan

Sekar

Kumaran

et al. 2012

International Journal of Biological Macromolecules

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Section: Preparation Of Silver Nanoparticles Using Chitosan (Ch-agnp)mentioning

confidence: 99%

Preparation, characterization and evaluation of biocomposite films containing chitosan and sago starch impregnated with silver nanoparticles

Arockianathan

Sekar

Kumaran

et al. 2012

International Journal of Biological Macromolecules

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“…Synthetic hydroxyapatite is prepared using a variety of chemical synthesis routes and reagents. Some of the techniques include wet processing (Monma and Kamiya 1987), dry processing (Fowler 1974), synthesizing via biological tissues (Liji Sobhana et al 2009;Sundaraseelan and Sastry 2007), sol-gel techniques (Yoshio et al 1990), electrochemical deposition etc. In our earlier studies, we have prepared calcined bone-based bone graft, and characterized and evaluated the same for its bone inducing capacity.…”

Section: Introductionmentioning

confidence: 99%

Preparation and characterization of a novel bone graft composite containing bone ash and egg shell powder

Krithiga

Sastry

2011

Bull Mater Sci

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Egg shells which were hitherto discarded as wastes were collected, purified and powdered into a particle size in the range of 5-50 μm. A composite bone graft material in cylindrical form was prepared using egg shell powder (ESP), bone ash (BA) and gelatin. These bone grafts were characterized for their FT-IR, TGA, XRD, SEM and mechanical properties. The mechanical studies indicate that the composite having a stoichiometric ratio of BA (3 g) and ESP (7 g) has shown better mechanical properties. X-ray diffraction (XRD) data indicated the crystallographic nature of BA is akin to hydroxyapatite (HA) and both BA and ESP did not lose their crystalline nature when bone grafts were prepared. This revealed that ESP may be used as a component in bone graft utilizing the solid waste from the poultry industry.

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“…After soaking, the scaffolds was dried at 120ºC for 1 day and the rates of weight loss of the scaffolds were measured with different Au NPs contents as a function of soaking time in SBF [28].…”

Section: In Vitro Degradation Test Of the Scaffoldmentioning

confidence: 99%

Evaluation, Characterization and Cell Viability of Ceramic Scaffold and Nano-gold loaded Ceramic Scaffold for Bone Tissue Engineering

Aly¹,

Eldesouky²,

Eid

2012

Am. J. Biomed. Sci.

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Orthopaedic implants and metal implantation are major technological contributions in the field of orthopaedic surgery. However, bacterial infection and inflammation are predicament issues that subsequently lead to implant failure and second surgery. Ceramic scaffold loaded with gold nanoparticles (Au NPs) posse's antimicrobial and anti-inflammatory properties, which would be more ideal for successful bone implantation and tissue regeneration. Thereby, Hydroxyapatite nanoparticles (nHA), β-Tricalcium Phosphate nanoparticles (nβ-TCP), and Au NPs were used for the fabrication of ceramic scaffold and Au NPs loaded ceramic scaffold. The effects of the Au NPs on the scaffold's mechanical properties, porosity and cell growth have been evaluated. Scanning Electron Microscope [1] and test metric universal testing machine were employed for characterization of the scaffolds. Gold loaded scaffold demonstrated enhanced porosity, degradability and mechanical properties compared with the ceramic scaffold. The porosity of the ceramic and Au NPs loaded ceramic scaffold ranged between 30-50% and 60-75%, respectively, while compressive strength ranged between 10-30mPa and 25-45mPa, respectively.. Scaffold synthesis can be used for implantation in organs that need high load bearing such as femurs, tibia and also as a substrate for Au NPs delivery. To our knowledge, Au NPs have not been incorporate previously with calcium phosphate for fabrication scaffold for bone grafting. Also this study the first report on the effects of Au NPS on the mechanical properties, porosity and degradation rates of ceramic scaffolds.

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Gelatin–Chitosan composite capped gold nanoparticles: a matrix for the growth of hydroxyapatite

Cited by 47 publications

References 30 publications

Preparation, characterization and evaluation of biocomposite films containing chitosan and sago starch impregnated with silver nanoparticles

Preparation, characterization and evaluation of biocomposite films containing chitosan and sago starch impregnated with silver nanoparticles

Preparation and characterization of a novel bone graft composite containing bone ash and egg shell powder

Evaluation, Characterization and Cell Viability of Ceramic Scaffold and Nano-gold loaded Ceramic Scaffold for Bone Tissue Engineering

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