Glandular odontogenic cyst of the mandible

Chavez, Julie A.; Richter, Kenneth J.

doi:10.1016/s0278-2391(99)90291-4

Cited by 21 publications

(7 citation statements)

References 13 publications

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“…Literature review shows that GOC may mimic a wide clinicopathologic spectrum ranging from lateral periodontal cyst to a destructive malignant neoplasm such as Central Mucoepidermoid Carcinoma [1–3, 5–7, 11–13, 16–21]. …”

Section: Discussionmentioning

confidence: 99%

Glandular Odontogenic Cyst: Report of Two Cases and Review of Literature

Anuthama

Sherlin

Ramalingam

et al. 2009

Head and Neck Pathol

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Glandular odontogenic cyst (GOC) is an uncommon jaw bone cyst of odontogenic origin described in 1987 by Gardner et al. It is a cyst having an unpredictable and potentially aggressive behaviour. It also has the propensity to grow to a large size and tendency to recur with only 111 cases having been reported thus far. The first case occurred in a 42-year-old female and presented as a localized swelling extending from 19 to 29 regions. There was a history of traumatic injury at the site. There was evidence of bicortical expansion and radiographs revealed a multilocular radiolucency. The second case occurred in a 21-year-old male, as a large swelling in the mandible and radiograph revealed radiolucency in the region. On histopathological examination, these lesions were diagnosed as GOC. It was concluded that, two cases submitted by us correlate with the existing literature that GOC’s affect more commonly in the middle age group, having predilection for mandible and that trauma could be a precipitating factor for its occurrence. The increased recurrence rates can be due to its intrinsic biological behavior, multilocularity of the cyst, and incomplete removal of the lining following conservative treatment.

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Section: Discussionmentioning

confidence: 99%

Glandular Odontogenic Cyst: Report of Two Cases and Review of Literature

Anuthama

Sherlin

Ramalingam

et al. 2009

Head and Neck Pathol

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“…To date, a total of 111 cases of GOC have been reported in 48 articles in the English language literature, approximately half of these in the last 7 years (Padayachee and Van Wyk, 1987; Gardner et al , 1988; Ficarra et al , 1990; Lindh and Larsson, 1990; Patron et al , 1991; Sadeghi et al , 1991; Van Heerden et al , 1992; Gardner and Morency, 1993; De Carvalho et al , 1994; Semba et al , 1994; Takeda, 1994; Toida et al , 1994; Economopoulou and Patrikiou, 1995; Hussain et al , 1995; High et al , 1996; Ide et al , 1996; Savage et al , 1996; Baliga et al , 1997; Machade de Sousa et al , 1997; Magnusson et al , 1997; Manojlovic et al , 1997; Ramer et al , 1997; Koppang et al , 1998; Chavez and Richter, 1999; Damm and Fantasia, 2000; Jose et al , 2000; Lin et al , 2000; Tosios et al , 2000; Barreto et al , 2001; Bhatt et al , 2001; Babburi et al , 2003; Ertas et al , 2003; Geist et al , 2003; Manor et al , 2003; Ferreira et al , 2004; Pires et al , 2004; Tran et al , 2004; Abu‐Id et al , 2005; Demetriades et al , 2005; Kaplan et al , 2005a; Lo Muzio et al , 2005; Qin et al , 2005; Velez, 2006; Kasaboglu et al , 2006; Shen et al , 2006; Sittitavornwong et al , 2006).…”

Section: Incidence and Prevalencementioning

confidence: 99%

Glandular odontogenic cyst: a challenge in diagnosis and treatment

2008

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The present review analyzes the accumulated data from all cases of glandular odontogenic cyst (GOC) reported in the English language literature. In the 20 years since it was first described, 111 cases have been reported, an incidence of 0.2% of odontogenic cysts. The age range is 14-75, mean 45.7, with a M/F ratio of 1.3:1. GOC has a predilection for the mandible (70%), affecting both anterior and posterior areas. It is typically radiolucent, well defined, either unilocular (53.8%) or multilocular (46.2%). Frequent perforation (61%) and of thinning of cortical plates (24.4%) indicate aggressiveness. Sufficient follow-up indicates that 30% of cases can recur. Treatment by enucleation or curettage carries the highest risk for recurrence, especially in large and multilocular lesions. Peripheral osteoectomy or marginal resection can eliminate the risk. Defined criteria for microscopic diagnosis are described, which in addition to Ki67 and p53 can help in differentiating GOC from lesions with histological similarities (cysts with mucous metaplasia, botryoid and surgical ciliated cysts, low-grade mucoepidermoid carcinoma). Definite diagnosis may not be possible in small incisional biopsies due to the focal presentation of characteristic features required for diagnosis. There is now evidence to support an odontogenic rather than a sialogenic origin.

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“…[ 12 ] The identification of superficial cuboidal cells, epithelial whorls, ciliated cells, and intraepithelial microcysts highly suggests GOC in differentiating GOC and low-grade mucoepidermoid carcinoma. [ 13 ]…”

Section: Discussionmentioning

confidence: 99%

Glandular odontogenic cyst: Case series

et al. 2017

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Glandular odontogenic cyst (GOC) is an uncommon and aggressive jaw cyst with a high recurrence rate. It may grow into a large size. Diagnosis of the cyst is challenging since it may be confused with some other jaw cysts and malignancies. Treatment methods vary from conservative surgery to radical bone resection. In this case series, we briefly present five cases of GOC diagnosed and treated at our clinic. Thorough histopathological diagnosis and long-term follow-up are necessary in patients with GOC.

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Glandular odontogenic cyst of the mandible

Cited by 21 publications

References 13 publications

Glandular Odontogenic Cyst: Report of Two Cases and Review of Literature

Glandular Odontogenic Cyst: Report of Two Cases and Review of Literature

Glandular odontogenic cyst: a challenge in diagnosis and treatment

Glandular odontogenic cyst: Case series

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