Helicobacter pylori colonization of the adenotonsillar tissue: Fact or fiction?

There has been conflicting results regarding the presence of H. pylori in tonsillar tissue. Our objective was to analyze for the presence of H. pylori in tonsillar tissue in patients undergoing tonsillectomy for chronic recurrent tonsillitis using rapid urease test in a Tertiary care academic medical center in a sub Saharan hospital. A prospective cross-sectional analysis of 39 consecutive cases of patients undergoing tonsillectomy secondary to chronic recurrent tonsilitis was done. Rapid urease test was conducted on each tonsillectomy tissue and results were determined using color change at specific time intervals within 24 h. Average age of the patients was 4.3 years. Among the 39 tonsillar tissues analysed using rapid urease test, H. pylori was present in 30.5 % of the samples. Colonisation by H. pylori of the palatine tonsils is a new frontier with conflicting results depending on the accuracy of the test method used and population studied. More studies need to be performed to ascertain the different rates of colonisation based on geographical regions.

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“…Other studies have disputed the presence of H. pylori in extra gastric reservoirs, including tonsil tissue [12,13].…”

Section: Discussionmentioning

confidence: 99%

“…The human palatine tonsil has been proposed as one of the extra gastric reservoirs of H. pylori and various studies have been undertaken to study its role [7][8][9][10][11]. Other studies dispute the fact that the human palatine tonsil may be an extragastric reservoir of H. pylori [12,13].…”

Section: Introductionmentioning

confidence: 99%

Prevalence of H. Pylori in Tonsillar Tissue of Patients with Chronic Recurrent Tonsillitis Using Rapid Urease Test in a Tertiary Referral Hospital in Sub Saharan Africa

Ochung’o

Mugwe

Masinde

et al. 2014

Indian J Otolaryngol Head Neck Surg

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“…Because it may affect the treatment methods, it is extremely important to clarify the etiology. There have been studies reported in the recent years [7][8][9][10]. H. pylori is a gram-negative, spiral-shaped microorganism that mainly exists in the gastric mucosa [11 12].…”

Section: Discussionmentioning

confidence: 99%

“…According to these routes of transmission, there are reported studies on the colonization of H. pylori in upper respiratory tract and oral mucosa [5][6][7]. In the recent years, adenotonsillar tissue has being started to be considered as one of the reservoir for the microorganism [8].…”

Section: Introductionmentioning

confidence: 99%

Is Helicobacter Pylori a Possible Etiopathogenic Factor in Chronic Tonsillitis?

Ozgun¹

2015

Ann Clin Anal Med

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Anahtar KelimelerHelikobakter Pilori; Tonsillektomi; Tonsil; Tonsillit; Giemsa Abstract Aim: Helicobacter pylori is the major gastric pathogen which has an important role in the etiopathogenesis of chronic gastritis. We investigated the presence of Helicobacter pylori as an extragastric reservoir in the tonsillectomy specimens to display if it is an etiologic factor in the development of chronic tonsilitis. Material and Method: In the current study, 100 cases with chronic tonsilitis were examined in bilateral tonsillectomy specimens. The colonization of the microorganism have been evaluated with hematoxylineosin and giemsa stains under the light microscope.Results: Helicobacter pylori has been detected in 33 cases (33%) on one side of the bilateral tonsillectomy specimens while it has been seen in 15 cases (15%) on both sides which demonstrated positivity in 48 cases (48%) in total. No colonization has been observed in the remaining 52 cases (52%). Discussion: Due to the considerable positivity in our study, the histopathologic evaluation of tonsillary Helicobacter pylori colonization may be instrumental in the etiologic association with chronic tonsillitis.

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“…It is known to be present in the oropharyngeal area in subgingival plaques, dental plaques and saliva (1). In recent years, research has shown its presence in middle ear effusions and tonsil and adenoid tissues (8,9).…”

Section: Discussionmentioning

confidence: 99%