Hexamethylenetetramine grafted layered double hydroxides as a novel and green heterogeneous ionic liquid catalyst for the synthesis of pyrido[2,3-d]pyrimidine derivatives

Synthesis of pyrido[2,3‐d:5,6‐d′]dipyrimidines using CuFe2O4/KCC‐1/PMA as a novel and efficient nanocatalyst under solvent‐free conditions

“…Heterocyclic compounds are an important group of organic compounds due to various biological and medicinal activities and existence in the structure of the natural products. [1][2][3] Pyrido[2,3-d:5,6-d 0 ]dipyrimidines [4,5] are a specific group of the heterocyclic compounds which containing pyrimidine ring in their structure. Pyridodipyrimidine derivatives have many biological activities such as antitumor, [6] inhibiting dihydrofolate reductases or tyrosine kinases, [7] anti-inflammatory, [8] antifolate, [9] antihypertensive, [10] antibacterial, [11] anti-HIV, [12] anticonvulsants, [13] antimicrobial, [14] calcium channel antagonists, [15] analgesic, [16] tuberculostatic, [17] and potassium sparing.…”

Review on synthesis of pyrrole derivatives promoted by nanoparticles

“…Magnetic nanoparticles (MNPs) [54,55a,b] [56] and separation of these nanoparticles in comparison to other nanoparticles is comfortable and easily separated from the reaction mixture using an external magnet [57] and has the capability of recovery and reusability for several times. In recent years, synthesis of different heterocycle compounds such as pyrroles, pyridopyrimidines, [58] pyranes, [59] pyridines, [59] pyrazolopyranopyrimidines, [60] thiazoles, [61] tetrazoles, [62] quinazolines, [63] polyhydroquinolines [63] derivatives, and some other heterocycles, using nanoparticles due to the advantages of this catalysts in compare to homogeneous and heterogeneous catalysts, is increased.…”

Zn (II)‐Schiff base covalently anchored to CaO@SiO2: A hybrid nanocatalyst for green synthesis of 4H‐pyrans

“…According to the principals of green chemistry, the use of green reaction conditions including nontoxic stating materials and elimination of hazardous materials has become a huge challenge in academic and industry aspects. [1] Multicomponent reactions (MCRs) are a green and powerful strategy for the synthesis of different biologically active organic compounds. These reactions have many useful advantages over traditional multistep processes including short reaction times, low costs, high efficiency, atom economy, and environmentally friendliness.…”

“…According to the principals of green chemistry, the use of green reaction conditions including nontoxic stating materials and elimination of hazardous materials has become a huge challenge in academic and industry aspects. [ 1 ]…”