High electrochemiluminescence of a new water-soluble iridium(iii) complex for determination of antibiotics

Abstract

A new water-soluble iridium(III) diimine complex with appended sugar was synthesized and characterized. The electrochemiluminescent behavior of the new complex in aqueous buffer was first studied and the ECL signal was found to be much higher than that of [Ru(bpy)(3)](2+) at a Pt working electrode. Tri-n-propylamine (TPA) and antibiotics were determined by the ECL of the iridium(III) complex in aqueous buffer at the Pt electrode and the method was found to show good sensitivity and reproducibility. The new iridium(III) complex was found to display good solubility in aqueous solution and a strong ECL signal at the Pt electrode, which might open up the possibility of its application in analysis.

Highly sensitive homogeneous electrochemical aptasensor for antibiotic residues detection based on dual recycling amplification strategy

“…Therefore, the detection of AMP residues in foodstuffs is very important for human health protection. In the past decades, many efforts have been made to develop efficient methods to detect the AMP residues in agricultural products and waters, including immunoassay (Kloth et al 2009), high-performance liquid chromatography-mass spectrometry (Chen et al 2015;Cheng et al 2015;Kipper et al 2011;Meng et al 2015;Straub and Voyksner 1993;Tylova et al 2013), nuclear magnetic resonance (Reinscheid 2006), colorimetry (Khan et al 2015;Xu et al 2004), fluorescence detection (Fernández.González et al 2003;Pena et al 2010), raman spectroscopy (Andreou et al 2015), electrochemiluminescence (Li et al 2011) and dual fluorescence-colorimetric biosensor (Song et al 2012). For example, Ban's group developed an aptasensor to detect AMP using its single-stranded DNA aptamer and gold nanoparticles-based dual fluorescence-colorimetric method (Song et al 2012a).…”

Synthesis of Iridium(III) Complex Bearing 1-Thio-β-D-glucose Tetraacetate Moieties and its Photogeneration of Singlet Oxygen

“…Ir(III) has also been reported in a pioneering synthetic study [11,12]. For photogeneration of singlet oxygen, iridium complexes having 2-phenylpyridinato ligand (ppy) are noteworthy that they emit phosphorescence in the visible light region with high quantum yields and their absorption properties (λ max ) can be tuned by modifying the ligands [13].…”

Electrogenerated chemiluminescence from newly synthesized α-diimine-ligated heteroleptic iridium(III) complexes

“…Lee and coworkers reported the synthesis and characterization of new iridium complexes of (pq) 2 Ir(acac) and (pq) 2 Ir(tmd) (pq = 2-phenylquinoline anion, acac = acetylacetonate anion, and tmd = 2,2′,6,6′-tetramethylhepta-3,5-dione anion) with much higher ECL efficiencies at 589 and 593 nm compared to that of Ru(bpy) 3 2+ [16]. Subsequently, a large number of novel iridium(III) complexes with various ligands have been prepared for ECL studies [17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32]. In particular, heteroleptic iridium(III) complexes such as Ir(dfppy) 2 (bpy) [27] and Ir(dfppy) 2 (PyBiz) [32] (dfppy = 2-(2,4-difluorophenyl) pyridine, PyBiz = 2-(2-pyridyl)benzimidazolato-N,N′) as the primary cyclometalating ligand have shown the highly enhanced ECL response compared to that of Ru(bpy) 3 2+ .…”

“…Among those heavy-metal complexes, cyclometalated iridium(III) complexes are, in particular, given strong attention as promising ECL emitters especially for the development of bright OLEDs in flat panel displays and highly sensitive ECL detection because they exhibit high ECL efficiency . Up to now, The cyclometalated iridium(III) complexes have been applied for the ECL detection of the antibiotics [19], ammonium ion [20], cancer cell [21], ammonia [24], and cytosensing [26]. Since the ECL emission wavelengths in cyclometalated iridium(III) complexes can be tuned from the near-infrared to blue via changing the structure of the ligand, they are particularly useful in the development of multichannel ECL-based assays [15,28,32].…”