How an aging society affects the economic costs of inactivity in Germany: empirical evidence and projections

Dallmeyer, Sören; Wicker, Pamela; Breuer, Christoph

doi:10.1186/s11556-017-0187-1

Cited by 25 publications

(16 citation statements)

References 41 publications

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“…Maresova [15] obtained estimates of different magnitudes for the Czech Republic; according to her results, the costs of physical inactivity were equal to 0.4% of total healthcare costs. Dallmeyer et al [16] estimated the costs of inactivity in the context of population ageing in Germany and is the only study to address physical inactivity and population ageing together. To do so, they estimated the proportion of a given disease that could be attributed to physical inactivity for five selected diseases and accordingly calculated the total costs of inactivity.…”

Section: Introductionmentioning

confidence: 99%

Physical Activity and Healthcare Costs: Projections for Poland in the Context of an Ageing Population

Kalbarczyk

Mackiewicz-Łyziak

2019

Appl Health Econ Health Policy

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Background The proportion of older people in many countries, including Poland, is expected to increase, which will lead to a rise in healthcare costs. Objectives This study aims to analyse the impact of older adults’ physical activity on public spending on healthcare in Poland over the long term. Method To include the physical activity factor needed for our long-term projections, we modified the macro-simulation model used by the European Commission in Poland. We used the Survey of Health, Ageing and Retirement in Europe database to calculate the number of healthcare users depending on their level of physical activity. We used three measures of healthcare users: people with chronic diseases, people who were in hospital or visited a doctor more than once in the previous year, and people who subjectively evaluated their health as fair or poor. Results We found that a higher level of physical activity in older adults is associated with lower public expenditure on healthcare for all measures adopted. However, the magnitude of this effect differed depending on the measure used, with gains ranging from 0.4 to 1.2% of gross domestic product per year by the end of the projection horizon. Conclusion Our findings provide a strong argument for social policy in Poland to intensify the promotion of physical activity in society to decrease future healthcare costs of older adults.

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Section: Introductionmentioning

confidence: 99%

Physical Activity and Healthcare Costs: Projections for Poland in the Context of an Ageing Population

Kalbarczyk

Mackiewicz-Łyziak

2019

Appl Health Econ Health Policy

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“…It is predicted that by the year 2050, the number of Americans over 85 years of age will triple from 2015 (United Nations Department of Economic and Social Affairs, 2015; Jaul and Barron, 2017). Larger percentages of the elderly and their increased risk for diseases can affect the economy, and social and health care costs (Dallmeyer et al, 2017). For instance, immune system dysfunction and cognitive decline due to aging increases the risk of neurodegenerative diseases, such as Alzheimer's disease (AD) (Jevtic et al, 2017; Mattson and Arumugam, 2018).…”

Section: Introductionmentioning

confidence: 99%

Data-Driven Analysis of Age, Sex, and Tissue Effects on Gene Expression Variability in Alzheimer's Disease

Brooks

Mias

2019

Front. Neurosci.

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Alzheimer's disease (AD) has been categorized by the Centers for Disease Control and Prevention (CDC) as the 6 th leading cause of death in the United States. AD is a significant health-care burden because of its increased occurrence (specifically in the elderly population), and the lack of effective treatments and preventive methods. With an increase in life expectancy, the CDC expects AD cases to rise to 15 million by 2060. Aging has been previously associated with susceptibility to AD, and there are ongoing efforts to effectively differentiate between normal and AD age-related brain degeneration and memory loss. AD targets neuronal function and can cause neuronal loss due to the buildup of amyloid-beta plaques and intracellular neurofibrillary tangles. Our study aims to identify temporal changes within gene expression profiles of healthy controls and AD subjects. We conducted a meta-analysis using publicly available microarray expression data from AD and healthy cohorts. For our meta-analysis, we selected datasets that reported donor age and gender, and used Affymetrix and Illumina microarray platforms (8 datasets, 2,088 samples). Raw microarray expression data were re-analyzed, and normalized across arrays. We then performed an analysis of variance, using a linear model that incorporated age, tissue type, sex, and disease state as effects, as well as study to account for batch effects, and included binary interactions between factors. Our results identified 3,735 statistically significant (Bonferroni adjusted p < 0.05) gene expression differences between AD and healthy controls, which we filtered for biological effect (10% two-tailed quantiles of mean differences between groups) to obtain 352 genes. Interesting pathways identified as enriched comprised of neurodegenerative diseases pathways (including AD), and also mitochondrial translation and dysfunction, synaptic vesicle cycle and GABAergic synapse, and gene ontology terms enrichment in neuronal system, transmission across chemical synapses and mitochondrial translation. Overall our approach allowed us to effectively combine multiple available microarray datasets and identify gene expression differences between AD and healthy individuals including full age and tissue type considerations. Our findings provide potential gene and pathway associations that can be targeted to improve AD diagnostics and potentially treatment or prevention.

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“… 2 Economic evaluations have become increasingly integrated with demographic trends. 3 These data can provide unbiased estimates for the calculation of cost-effectiveness to suggest decisions on the effective and efficient use of health care resources. 4 , 5 For example, in the UK, the National Institute for Health Research’s Health Technology Assessment (HTA) program is involved in funding research, including clinical trials, to investigate the clinical relevance and cost-effectiveness of a range of health technologies (eg, medicines, devices, procedures, and screening) used to promote health, prevent and treat diseases, and improve rehabilitation and long-term care.…”

Section: Introductionmentioning

confidence: 99%

FIMA, the questionnaire for health-related resource use in the elderly population: validity, reliability, and usage of the Polish version in clinical practice

Mazurek¹,

Sutkowska²,

Szczęśniak³

et al. 2018

CIA

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PurposeThe purpose of this study was to determine the validity and reliability of the Polish version of the Questionnaire for Health-Related Resource Use in an Elderly Population [Fragebogen zur Inanspruchnahme medizinischer und nicht-medizinischer Versorgungsleistungen im Alter (FIMA)].Patients and methodsThis was a cross-sectional study conducted in a rehabilitation care unit in Poland between January and June of 2017. Sixty-one patients aged ≥65 years who had been admitted to the unit were enrolled into the study. Each participant was evaluated twice: once within 48 hours of admission (T1) and once after 2 weeks (T2).ResultsThe translated instrument was understood by most respondents in a selected population and it maintained a reading and comprehension level that was accessible by most respondents, even of a low education level. With the aid of the prevalence-adjusted bias-adjusted kappa (PABAK) and intraclass correlation coefficient (ICC), 100% test–retest reliability for 10 out of the 12 questions that were subjected to analysis was indicated. The most frequent health-related resource uses were appointments at the general practitioner (90.2%) and orthopedist (54.1%), medication (93.4%), and the necessity to have glasses as supportive equipment (70.5%).ConclusionThe Polish FIMA demonstrated very good test–retest reliability, good validity, and ease of use for elderly people. Further investigation is required. In the future, the routine use of this instrument could be encouraged to assess the use and demand for medical and nonmedical services among the elderly.

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How an aging society affects the economic costs of inactivity in Germany: empirical evidence and projections

Cited by 25 publications

References 41 publications

Physical Activity and Healthcare Costs: Projections for Poland in the Context of an Ageing Population

Physical Activity and Healthcare Costs: Projections for Poland in the Context of an Ageing Population

Data-Driven Analysis of Age, Sex, and Tissue Effects on Gene Expression Variability in Alzheimer's Disease

FIMA, the questionnaire for health-related resource use in the elderly population: validity, reliability, and usage of the Polish version in clinical practice

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