“…Barley ( Hordeum vulgare L), particularly, contains various phenolic compounds, which have been shown to have antioxidant activity and to be effective for improving health (Giriwono, Shirakawa, Hokazono, Goto, & Komai, 2011; Mattila, Pihlava, & Hellström, 2005; Pérez‐Jiménez & Saura‐Calixto, 2005), including anticancer (Robles‐Escajeda et al., 2013) and probiotic gastroprotective (Charalampopoulos, Pandiella, & Webb, 2003) activities. Fermentation procedures can lead to increase the availability of secondary metabolites and functionality of these phenolic compounds (Ye, Morimura, Han, Shigematsu, & Kida, 2004; Yoshimoto et al., 2004), especially the antioxidative effects (Giriwono et al., 2010, 2011). A number of barley extracts produced from fermentation have been reported to be potent pharmacological effects, especially antioxidant (Giriwono et al., 2011), uric acid lowering (Hokazono, Omori, Yamamoto, Akaoka, & Ono, 2010), antiatopic dermatitis (Hokazono, Omori, & Ono, 2010; Iguchi, Kawata, Watanabe, Mazumder, & Tanabe, 2009), hepatoprotective (Giriwono et al., 2010, 2011), and immunostimulatory (Kim et al., 2007) activities, compared with nonfermented extracts.…”