IL-6 gene promoter polymorphisms in Korean generalized aggressive periodontitis

Th2 cell regulatory and effector molecules single nucleotide polymorphisms and periodontitis

“…Twenty articles were found reporting rs1800796 of IL6 and periodontitis 20,43‐61 . Special attention was paid upon the full text and reported absolute values.…”

“…Twenty articles were found reporting rs1800796 of IL6 and periodontitis. 20,[43][44][45][46][47][48][49][50][51][52][53][54][55][56][57][58][59][60][61] Special attention was paid upon the full text and reported absolute values. Regarding articles on rs1800796 of IL6 and periodontitis, 2 of the 20 studies were suspected reporting data from almost same cohort, 49,52 and only the recent report with a bigger sample size was included in the final analysis.…”

“…20,51 Reports citing and cited by the included studies were looked up and no additional relevant study was detected. As a result, a total of 17 studies 20,[43][44][45]47,48,[50][51][52][53][54][56][57][58][59][60][61] together with data of the current study were finally included in the meta-analysis (Fig. 4, Supporting Information Table S4; controls = 2760, periodontitis = 2442).…”

Factors associated with gingival bleeding by tooth brushing in college students

“…치주질환의 위험요인으로는 치태, 연령, 사회･경제적 요인, 심리적 요인, 유전, 구강관리습관, 당뇨, 비만 등이 있 고, 또한 치주질환이 관상동맥질환, 뇌졸중, 조산, 저체중아 출산, 오연성 폐렴, 면역⋅알레르기질환 등에 영향을 주는 것으로 알려져 있다 3,10) . 치태관련 치은염은 치은에만 국한되고 부착소실이 없으 나 치주염은 치주낭 형성, 부착상실을 동반한 치은퇴축, 치 주인대와 치조골의 점진적 파괴를 초래한다, 치주염의 증상 은 치은에서 출혈이 있거나 잇몸이 붓고 시리며, 치아가 흔 들리거나 음식을 씹을 때 치아통증 등이 있다 7,11) . 특히 치 아상실은 저작능력 감소와 소화기능의 저하로 전신건강 및 발음과 외모에 영향을 주어 대인관계 및 사회생활에 큰 지 장을 준다 9) .…”