Immunology and Prevention of Infection in Feedlot Cattle

Roth, James A.; Perino, Louis J.

doi:10.1016/s0749-0720(15)30252-8

Cited by 11 publications

(14 citation statements)

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“…The interactions of stress, nutrition, and fertility with the innate and adaptive immune systems are important for cattle (Lippolis, 2008). The innate immune system (particularly phagocytic cell function), is susceptible to stress and nutrition impacts in cattle (Roth and Perino, 1998), and stress including social factors may impact their adaptive immune system (Salak-Johnson and McGlone, 2007).…”

Section: The Mammalian and Bovine Responses To Alphaherpesvirus Infecmentioning

confidence: 99%

Immunity to Bovine Herpesvirus 1: I. Viral lifecycle and innate immunity

Levings

Roth

2013

Anim. Health. Res. Rev.

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Bovine herpesvirus 1 (BHV-1) causes a variety of diseases and is globally distributed. It infects via mucosal epithelium, leading to rapid lytic replication and latent infection, primarily in sensory ganglia. Large amounts of virus can be excreted by the host on primary infection or upon recrudescence of latent infection, resulting in disease spread. The bovine immune response to BHV-1 is rapid, robust, balanced, and long-lasting. The innate immune system is the first to respond to the infection, with type I interferons (IFNs), inflammatory cytokines, killing of infected host cells, and priming of a balanced adaptive immune response. The virus possesses a variety of immune evasion strategies, including inhibition of type I IFN production, chemokine and complement binding, infection of macrophages and neutrophils, and latency. BHV-1 immune suppression contributes to the severity of its disease manifestations and to the bovine respiratory disease complex, the leading cause of cattle death loss in the USA. RightsWorks produced by employees of the U.S. Government as part of their official duties are not copyrighted within the U.S. The content of this document is not copyrighted. AbstractBovine herpesvirus 1 (BHV-1) causes a variety of diseases and is globally distributed. It infects via mucosal epithelium, leading to rapid lytic replication and latent infection, primarily in sensory ganglia. Large amounts of virus can be excreted by the host on primary infection or upon recrudescence of latent infection, resulting in disease spread. The bovine immune response to BHV-1 is rapid, robust, balanced, and long-lasting. The innate immune system is the first to respond to the infection, with type I interferons (IFNs), inflammatory cytokines, killing of infected host cells, and priming of a balanced adaptive immune response. The virus possesses a variety of immune evasion strategies, including inhibition of type I IFN production, chemokine and complement binding, infection of macrophages and neutrophils, and latency.

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Section: The Mammalian and Bovine Responses To Alphaherpesvirus Infecmentioning

confidence: 99%

Immunity to Bovine Herpesvirus 1: I. Viral lifecycle and innate immunity

Levings

Roth

2013

Anim. Health. Res. Rev.

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“…[1][2][3][4][5] In 1995, BRDC cost beef cattle producers nearly $500 million. 6 The most common infectious agents associated with BRDC are Mannheimia haemolytica, Pasteurella multocida, Haemophilus somnus, bovine herpesvirus type 1 (BHV-1), bovine viral diarrhea virus (BVDV), parainfluenza virus type 3 (PI3), and bovine respiratory syncytial virus (BRSV).…”

mentioning

confidence: 99%

“…6 The most common infectious agents associated with BRDC are Mannheimia haemolytica, Pasteurella multocida, Haemophilus somnus, bovine herpesvirus type 1 (BHV-1), bovine viral diarrhea virus (BVDV), parainfluenza virus type 3 (PI3), and bovine respiratory syncytial virus (BRSV). 4 Substantial epidemiologic and experimentally derived data have been used to document the relationship between viral and bacterial pathogens and their combined contribution to the incidence of pneumonia in cattle. 4,[7][8][9] The complexity of this pathogenic synergism makes accurate diagnosis and treatment difficult.…”

mentioning

confidence: 99%

“…4 Substantial epidemiologic and experimentally derived data have been used to document the relationship between viral and bacterial pathogens and their combined contribution to the incidence of pneumonia in cattle. 4,[7][8][9] The complexity of this pathogenic synergism makes accurate diagnosis and treatment difficult. Development of an analytic tool to indicate the health status of feedlot cattle would be valuable to food animal veterinarians as well as the beef cattle industry.…”

mentioning

confidence: 99%

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Relationship of vitamin E supplementation and antimicrobial treatment with acute-phase protein responses in cattle affected by naturally acquired respiratory tract disease

Carter¹,

Meredith²,

Montelongo³

et al. 2002

ajvr

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“…This in turn affects resistance of the host to microbial insults, uncontrolled proliferation of neoplastic cells and recrudescence of viral infections (Roth and Perino, 1998). Most d the research emphasis with stress and animal health has been laid to the study of heat and cold ambient conditions.…”

Section: Introductionmentioning

confidence: 99%