Implantable SiC based RF antenna biosensor for continuous glucose monitoring

Afroz, Shamima; Thomas, Sylvia; Mumcu, Gökhan; Saddow, Stephen E.

doi:10.1109/icsens.2013.6688379

Cited by 29 publications

(34 citation statements)

References 23 publications

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“…The material also is a semiconductor, and as such can be fabricated into electrical devices which can be used for sensing or signal reception and transmission. We have shown that the crystalline form of this material does not cause cytotoxic response in vitro and has not initiated chronic inflammatory response within animal models in vivo [41,44,57,128,155]. We have shown that it is a promising material to solve the longevity and reliability issues plaguing both continuous glucose monitors as well as neural implants [41,44,128,155].…”

Section: Sic Biomedical Perspectivesmentioning

confidence: 93%

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Silicon Carbide Materials for Biomedical Applications

Frewin

Coletti

et al. 2014

Carbon for Sensing Devices

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Section: Sic Biomedical Perspectivesmentioning

confidence: 93%

“…The sensing mechanism is based upon a shift in resonant frequency as a function of change in glucose levels which electrically manifests itself as a change in blood permittivity and conductivity (Fig. 7.18b) [127,128].…”

Section: Glucose Sensormentioning

confidence: 99%

Silicon Carbide Materials for Biomedical Applications

Frewin

Coletti

et al. 2014

Carbon for Sensing Devices

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“…Unlike biosensors that require direct contact with interstitial fluids to trigger chemical reactions to operate, this biocompatible SiC sensor doesn't require a direct interface [39]. The sensing mechanism is based upon a shift in resonant frequency as a function of change in glucose levels which electrically manifests itself as a change in blood permittivity and conductivity [40,41].…”

Section: Continuous Glucose Sensormentioning

confidence: 99%

3C-SiC on Si: A Versatile Material for Electronic, Biomedical and Clean Energy Applications

Frewin

Reyes

et al. 2014

MRS Proc.

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Silicon carbide (SiC) has long been known as a robust semiconductor with superior properties to silicon for electronic applications. Consequently a tremendous amount of international activity has been on-going for over four decades to develop high-power solid state SiC electronics. While this activity has focused on the hexagonal polytypes of SiC, the only form that can be grown directly on Si substrates, 3C-SiC (or cubic SiC), has been researched for non-electronic applications such as MEMS and biosensors. In particular in our group we have pioneered several biomedical devices using 3C-SiC grown on Si substrates, and recently have been investigating the use of this novel material for clean energy applications. This paper first reviews progress made in the area of 3C-SiC electronic devices. Next a review of nearly a decade of biomedical activity is presented, with particular emphasis on the most promising applications: in vivo glucose monitoring, biomedical implants for connecting the human nervous system to advanced prosthetics, and MEMS/NEMS research aimed at allowing for in vivo diagnostic and therapeutic systems for advanced biomedical applications. Recent published work in the area of hydrogen production via electrolysis using 3C-SiC closes the paper as this last application is extremely promising for the burgeoning hydrogen economy and demonstrates a third important application of 3C-SiC on Si -its potential use in clean energy systems.

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“…3 shows experimental setup, which represents as an antenna is placed in the human body, near to high-density blood vessels. Synthetic blood fluid was prepared by dissolving the appropriate quantities of 9 separate chemicals in distilled water [2]. Four different samples of 50 ml each were made with different glucose levels for different diabetic conditions as shown in the Table 1.…”

Section: Experimental Verificationmentioning

confidence: 99%

“…These biosensors rely on interstitial fluids within the dermis to measure interstitial glucose level (IG) and can function only for 10 to 30 days after implantation in the body. They may degrade or fail and may damage surrounding tissues [2]. To increase the functional time of implant sensor, the proper biocompatible design should take into consideration.…”

Section: Introductionmentioning

confidence: 99%

Design of Implantable MSA for Glucose Monitoring

Khadase¹,

Nandgaonkar²

2017

Proceedings of the International Conference on Communication and Signal Processing 2016 (ICCASP 2016)

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Abstract. The emerging techniques in the sensor field include an antenna as a bio-sensor. A simple Planar Inverted F antenna (PIFA) as an implantable glucose sensor to detect variation in glucose level is presented in this paper. The work includes design of PIF antenna using HFSS software and in vitro testing as a sensor with various glucose level in synthetic blood. The antenna is designed to resonate at frequency 530 MHz for demonstration purpose. The shift in the resonant frequency of 3.54 kHz per 1 mg/dl is observed with respect to change in glucose level concentration.

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Implantable SiC based RF antenna biosensor for continuous glucose monitoring

Cited by 29 publications

References 23 publications

Silicon Carbide Materials for Biomedical Applications

Silicon Carbide Materials for Biomedical Applications

3C-SiC on Si: A Versatile Material for Electronic, Biomedical and Clean Energy Applications

Design of Implantable MSA for Glucose Monitoring

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