Improving the management procedures in farms infected with the Porcine Reproductive and Respiratory Syndrome virus using PDP models

Colomer, M. Angels; Margalida, Antoni; Fraile, Lorenzo

doi:10.1038/s41598-019-46339-w

Cited by 9 publications

(15 citation statements)

References 38 publications

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“…Porcine reproductive and respiratory syndrome virus (PRRSV), swine influenza virus (SIV) and porcine circovirus type 2 virus (PCV2) are the most prevalent viral agents [1][2][3][4][5][6]. On the other hand, many non-infectious predisposing factors are also involved in PRDC, such as poor environmental conditions, density, stressors, season of the year, genetic background and production flow (all-in-all out versus continuous flow) [7][8][9]. As a general approach, preventive medicine programs should be based on applying measures to control PRDC in a cost-effective way, such as improving environmental conditions, decreasing density and stressors, combined with vaccination against the major viral and bacterial infectious etiologic factors [10].…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial Susceptibility Pattern of Porcine Respiratory Bacteria in Spain

Vilaró¹,

Novell²,

Enrique-Tarancón³

et al. 2020

Antibiotics

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The monitoring of antimicrobial susceptibility of pig pathogens is critical to optimize antimicrobial treatments and prevent development of resistance with a one-health approach. The aim of this study was to investigate the antimicrobial susceptibility patterns of swine respiratory pathogens in Spain from 2017 to 2019. Bacterial isolation and identification were carried out following standardized methods from samples coming from sacrificed or recently deceased pigs with acute clinical signs compatible with respiratory tract infections. Minimum inhibitory concentration (MIC) values were determined using the broth microdilution method containing a total of 10 and 7–8 antimicrobials/concentrations respectively, in accordance with the recommendations presented by the Clinical and Laboratory Standards Institute (CLSI). The obtained antimicrobial susceptibility varies between pig respiratory pathogens. Actinobacillus pleuropneumoniae (APP) and Pasteurella multocida (PM) were highly susceptible (≥90%) to ceftiofur, florfenicol and macrolides (tilmicosin, tildipirosin and tulathromycin). However, the antimicrobial susceptibility was intermediate (>60% but <90%) for amoxicillin and enrofloxacin in the case of APP and sulfamethoxazole/trimethropim and tiamulin in the case of PM. Both bacteria showed low (<60%) antimicrobial susceptibility to doxycycline. Finally, Bordetella bronchiseptica was highly susceptible only to tildipirosin and tulathromycin (100%) and its susceptibility for florfenicol was close to 50% and <30% for the rest of the antimicrobial families tested. These results emphasize the need of determining antimicrobial susceptibility in pig respiratory cases in order to optimize the antimicrobial treatment in a case-by-case scenario.

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Section: Introductionmentioning

confidence: 99%

Antimicrobial Susceptibility Pattern of Porcine Respiratory Bacteria in Spain

Vilaró¹,

Novell²,

Enrique-Tarancón³

et al. 2020

Antibiotics

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“…двічі з інтервалом 3 тижні. У разі виникнення хвороби заходи боротьби з мікоплазмозом свиней грунтуються на розриві епізоотичної ланцюга, запобіганні контакту між хворими та здоровими тваринами, поліпшенні умов утримання, годівлі та виключення стресових чинників, що знижують резистентність організму (Colomer, Margalida, & Fraile, 2019;Nathues et. al., 2013).…”

Section: актуальність темиunclassified

Etiology of porcine enzootic pneumonia and control strategies on the farms of Zaporizhzhya and Poltava regions

Golovko¹,

Severyn²,

Ivanchenko³

et al. 2019

VTTP

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Porcine enzootic pneumonia is a multifactorial disease, it leads to large and significant economic losses in pig farms and it remains a relevant veterinary problem. The involvement of new etiological agents in the association of pathogens and the constantly changing conditions on the farms lead to the fact that previously developed control schemes and methods of disease lost their effectiveness. Therefore, the identification of all the infectious agents that make up the association, as well as the concomitant factors that led to the occurrence of the disease in each case is the only correct way to control measures.When we studied the situation in pig farms in the south and in the central region of Ukraine, we found that mycoplasmas were the main etiological agent for Porcine enzootic pneumonia. We noted that mycoplasmosis as a monoinfection was recorded only in 9-12 % of cases. In most outbreaks Mycoplasmas were only members of associations along with Porcine reproductive and respiratory syndrome infection (6%), Type 2 Circovirus infection (6%), enterbacterias (19%) and pasterellas (59%).The course of the disease was also aggravated by the stress of early weaning of piglets and violations of the conditions of feeding and animal welfare.The most difficult enzootic pneumonia occurred in those farms where mycoplasmosis and pasteurellosis were exacerbated by the presence of pathogens of actinobacillus pleuropneumonia. In such farms the average daily weight gain decreased in piglets by a third and feed consumption increased to 28 %.Piglets on affected farms were ill with obvious respiratory clinical signs. And 82% of dead or killed piglets had signs of fibrinous pleuropneumonia or catarrhal pneumonia.In those farms where we recorded associated respiratory infections, we also found reproductive-neonatal infections of pigs.In such farms treatment and prophylactic measures using traditional antimicrobial special remedies and monovaccines, did not give the expected effect.We proposed the use of autovaccines for associated enzootic pneumonia.

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“…Several studies have documented that the type of farm management practices and antibiotic use affect the incidence of swine respiratory diseases, including Glässer's disease [20][21][22]. For instance, Hurnik et al [23] reported several risk factors in the epidemiology of enzootic pneumonia such as feeding methods, housing type, farm size and management practices.…”

Section: Introductionmentioning

confidence: 99%

Variations in association of nasal microbiota with virulent and non-virulent strains of Glaesserella (Haemophilus) parasuis in weaning piglets

Mahmmod

Correa‐Fiz

Aragón

2020

Vet Res

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Glaesserella (formerly Haemophilus) parasuis causes Glässer's disease, which results in high economic loss in the swine industry. To understand the polymicrobial interactions of G. parasuis and the nasal microbiota, the statistical association patterns of nasal colonizing bacteria with virulent and non-virulent strains of G. parasuis were studied accounting for the farm management practices as potential risk factors for the occurrence of Glässer's disease. The nasal microbiota from 51 weaned-piglets from four farms with Glässer's disease and three farms with no respiratory diseases was previously characterized and included in this study. The presence of virulent and/or non-virulent G. parasuis strains in the nasal cavities was determined in order to establish the potential association with other members of the nasal microbiota. Multivariate logistic and linear regression models were performed among the various members of nasal microbiota and G. parasuis. The multi-site production system and disease presence in the farm were both significantly associated with the presence of G. parasuis virulent strains in the nose of the piglets. Differential bacterial associations were observed with virulent or non-virulent G. parasuis. Chitinophagaceae, Corynebacteriaceae and Corynebacterium were positively associated with the virulent G. parasuis strains, while Enterobacteriaceae, Peptostreptococcaceae, Clostridium XI, and Escherichia/Shigella were negatively associated with virulent G. parasuis. On the other hand, Flavobacteriaceae, Planobacterium, and Phascolarctobacterium were positively associated with the non-virulent G. parasuis strains, while Rikenellaceae, Enterococcaceae, Odoribacter, and Corynebacterium were negatively associated with non-virulent G. parasuis. In conclusion, the nasal microbiota communities showed variations in the association with the G. parasuis strains type.

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Improving the management procedures in farms infected with the Porcine Reproductive and Respiratory Syndrome virus using PDP models

Cited by 9 publications

References 38 publications

Antimicrobial Susceptibility Pattern of Porcine Respiratory Bacteria in Spain

Antimicrobial Susceptibility Pattern of Porcine Respiratory Bacteria in Spain

Etiology of porcine enzootic pneumonia and control strategies on the farms of Zaporizhzhya and Poltava regions

Variations in association of nasal microbiota with virulent and non-virulent strains of Glaesserella (Haemophilus) parasuis in weaning piglets

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