Inactivation of porcine epidemic diarrhea virus with electron beam irradiation under cold chain conditions

Liu, Yan; Shao, Yang; Wang, Lu; Lu, Weilai; Li, Shihua; Xu, Defu; Fu, Yu

doi:10.1016/j.eti.2022.102715

Cited by 6 publications

(5 citation statements)

References 75 publications

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“…PEDV and TGEV are structurally similar to SARS-CoV-2 according to previous reports ( Liu et al, 2022 ; Singh et al, 2021b ; Zhu et al, 2017 ). Their genomes encode three structural proteins: spike (S) glycoprotein, envelope (E) protein, and membrane (M) protein ( Tai et al, 2021 ).…”

Section: Discussionsupporting

confidence: 69%

“…According to Liu et al’ study, an irradiation dose of 10 kGy reduced the PEDV virus titer by 1.68–1.76 log10 TCID50/100 μL in a cold-chain environment (−20 °C) ( Liu et al, 2022 ). In this study, the D 10 values of PEDV and TGEV in DMEM and virus-inoculated Large yellow croaker are all less than 2 kGy ( Table 2 ).…”

Section: Discussionmentioning

confidence: 99%

“…Unlike SARS-CoV-2, PEDV and TGEV infect only pigs and can be easily cultured and processed in BSL2 facilities ( Singh et al, 2021a ). These two viruses are considered good surrogates to SARS-CoV-2 for their biophysiological properties and genomic structure are highly similar compared to SARS-CoV-2 ( Liu et al, 2022 ; Singh et al, 2021b ; Zhu et al, 2017 ).…”

Section: Introductionmentioning

confidence: 99%

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Inactivation of two SARS-CoV-2 virus surrogates by electron beam irradiation on large yellow croaker slices and their packaging surfaces

Luo

Zhou

et al. 2023

Food Control

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Section: Discussionsupporting

confidence: 69%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Inactivation of two SARS-CoV-2 virus surrogates by electron beam irradiation on large yellow croaker slices and their packaging surfaces

Luo

Zhou

et al. 2023

Food Control

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“…Historically, the irradiation of feed ingredients and complete diets has been shown to reduce the concentration of bacteria within feed and improves growth performance [15,16]. Additionally, irradiation has been shown to inactivate swine viruses including PEDV [8,17]. Given the high degree of efficacy for feed sanitation, irradiation has been commonly used in biomedical research settings to ensure that feed provided to animals is free of pathogenic agents.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Extended Storage of Swine Complete Feed for Inactivation of Viral Contamination and Effect on Nutritional, Microbiological, and Toxicological Profiles

Gebhardt,

Dee,

Little

et al. 2024

Animals

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The extended storage of feed ingredients has been suggested as a method to mitigate the risk of pathogen transmission through contaminated ingredients. To validate the approach of extended storage of complete swine feed for the inactivation of swine viruses, an experiment was conducted wherein swine feed was inoculated with 10 mL of 1 × 105 TCID50/mL of porcine reproductive and respiratory syndrome virus (PRRSV), porcine epidemic diarrhea virus (PEDV), and Senecavirus A (SVA) and stored for 58 d at 23.9 °C. Measures of feed quality were also evaluated at the initiation and conclusion of the storage period including screening for mycotoxins, characterization of select microbiological measures, and stability of phytase and dietary vitamins. Storing feed for 58 d under either ambient or anaerobic and temperature-controlled storage conditions did not result in substantial concerns related to microbiological profiles. Upon exposure to the feed following 58 d of storage in a swine bioassay, previously confirmed naïve pigs showed no signs of PEDV or SVA replication as detected by the PCR screening of oral fluids and serum antibody screening. Infection with SVA was documented in the positive control room through diagnostic testing through the State of Minnesota. For PRRSV, the positive control room demonstrated infection. For rooms consuming inoculated feed stored for 58 d, there was no evidence of PRRSV infection with the exception of unintentional aerosol transmission via a documented biocontainment breach. In summary, storing feed for 58 d at anaerobic and temperature-controlled environmental conditions of 23.9 °C validates that the extended storage of complete swine feed can be a method to reduce risks associated with pathogen transmission through feed while having minimal effects on measures of nutritional quality.

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“…In addition, the recent epidemics of global security issues such as the COVID-19 virus and monkeypox virus are caused by the spread of viruses that threaten all human beings and have a great impact on human production, life, and health [11][12][13][14]. Similar to bacteria and pathogenic microorganisms, epidemic viruses are always difficult to eradicate due to the abuse of antibiotics and various disadvantages of disinfectants [15,16]. In view of the above situation, it is crucial to explore more effective solutions and approaches.…”

Section: Introductionmentioning

confidence: 99%

Recent Progress in ZnO-Based Nanostructures for Photocatalytic Antimicrobial in Water Treatment: A Review

Xin

Wang

et al. 2022

Applied Sciences

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Advances in nanotechnology have led to the development of antimicrobial technology of nanomaterials. In recent years, photocatalytic antibacterial disinfection methods with ZnO-based nanomaterials have attracted extensive attention in the scientific community. In addition, recently widely and speedily spread viral microorganisms, such as COVID-19 and monkeypox virus, have aroused global concerns. Traditional methods of water purification and disinfection are inhibited due to the increased resistance of bacteria and viruses. Exploring new and effective antimicrobial materials and methods has important practical application value. This review is a comprehensive overview of recent progress in the following: (i) preparation methods of ZnO-based nanomaterials and comparison between methods; (ii) types of nanomaterials for photocatalytic antibacterials in water treatment; (iii) methods for studying the antimicrobial activities and (iv) mechanisms of ZnO-based antibacterials. Subsequently, the use of different doping strategies to enhance the photocatalytic antibacterial properties of ZnO-based nanomaterials is also emphatically discussed. Finally, future research and practical applications of ZnO-based nanomaterials for antibacterial activity are proposed.

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Inactivation of porcine epidemic diarrhea virus with electron beam irradiation under cold chain conditions

Cited by 6 publications

References 75 publications

Inactivation of two SARS-CoV-2 virus surrogates by electron beam irradiation on large yellow croaker slices and their packaging surfaces

Inactivation of two SARS-CoV-2 virus surrogates by electron beam irradiation on large yellow croaker slices and their packaging surfaces

Evaluation of Extended Storage of Swine Complete Feed for Inactivation of Viral Contamination and Effect on Nutritional, Microbiological, and Toxicological Profiles

Recent Progress in ZnO-Based Nanostructures for Photocatalytic Antimicrobial in Water Treatment: A Review

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