Incidence of Hashimoto's thyroiditis and its relationship to age, sex, smoking and blood groups.

Abstract

This study was aimed to demonstrate the incidence of Hashimoto's disease in Iraqi patients and its correlation to some of the sociodemographic features. The research groups involved (50 patients with Hashimoto?s disease and 50 healthy subjects). All of them were subjected to the estimation of levels of free triiodothyronine (FT3), free thyroxine (FT4), TSH, anti-thyroid peroxidase (anti-TPO), and anti-thyroglobulin (anti-Tg). The results demonstrated that there is a dramatic increase in the occurrence of HT in older patients. The age group (41-50 years old) was the most age group affected by Hashimoto's disease, followed by the age groups (31-40, 21-30, and 9-20 years old) respectively. A significant proportional correlation (R:0.952, P:0.024) was found between HT disease and aging. According to the gender, the results found that the vast majority (82%) of patients were females (P = 0.01). Also, the smoking percent was (40%) of patients. The presence of autoimmune thyroid disease in one or more individuals within the family (family history) was also evaluated and the results found that (28%) of the Hashimoto?s disease group have a positive family history of thyroid autoimmune diseases. It can be concluded from these results that females are more prone to developing Hashimoto?s disease compared to males, in other words, the female gender is a risk factor for the occurrence of autoimmune hypothyroidism. Also, the negative impact of smoking and family history gives an indication that these parameters are independent and don’t associate with Hashimoto?s disease at least in the current study.

Evaluation Serum levels of Leptin,CRP and Lipid profile in Hypothyroid Women in Kirkuk city/Iraq

“…The thyroid hormones are responsible of the basal metabolic rate (BMR) in hypothyroid status the decrease in the T3 and T4 concentration lead to a lack in the rate of the metabolism and that's why hypothyroidisim causes obesity [27] Our Findings Showed a significant difference (decrease) in serum T3 levels (P≤ 0.011) and T4 levels (P≤0.001) and a significant increase in TSH levels (P<0.001) in hypothyroid patients compared to the control group as shown in These results agreed with other results [28] and [29] and also with [24], Chin and his assistants estimated that the raising of TSH levels in hypothyroid patients would be a compensative response to counteract the decrease levels of THs trying of hypothalamus to acquire into a homeostasis [30].…”

Estimation of LH, FSH, Prolactin, Ferritin and Vitamin B12 of Hypothyroid Women in Kirkuk City/Iraq

“…The results showed a significant increase in serum TSH levels (P<0.001) and a significant decrease in serum levels T4 (P ≤ 0.001) and T3 (P≤0.011) in hypothyroid patients compared to control group as shown in Table 1 These findings agreed with [25] and [26] and also with [27] Chin and his assistants estimated that the raising of TSH levels in hypothyroid patients would be a compensative response to counteract the decrease levels of THs trying of hypothalamus to acquire into a homeostasis [28].…”

Research Title: ABO Blood Types Can Play a Role in Determining Prognosis of Thyroid Cancer in Adult Patients: A Single-centre Retrospective Study.

“…Tam Abass et al and Younus et al both reported a higher prevalence of thyroiditis among individuals with blood group O (57.3% and 52%, respectively) (21,32). A number of studies suggest that ABO blood type antigens may be associated with a general in ammatory response (33)(34)(35).…”