Infantile obesity: A situation of atherothrombotic risk?

Prevalence and Cluster of Cardiometabolic Biomarkers in Overweight and Obese Schoolchildren: Results from a Large Survey in Southwest Germany

“…This observation is consistent with findings from a study among German children 12 years old (31 ) and with a small case-control study from Spain (19 ). Fibrinogen correlates with inflammatory markers and plays a central role in the coagulation cascade (16 ).…”

“…Inflammatory markers such as interleukin (IL)- 6 (16 ) and in particular C-reactive protein (CRP) are considered risk factors for the metabolic syndrome (17 ) and cardiovascular disease (7 ). Fibrinogen, an acute-phase reactant that also plays a central role in the coagulation cascade, has been linked to obesity in adults (18 ) and children (19 ).…”

Association of metabolic biomarkers of cardiovascular disease in overweight and obese children in Emohua Local Government Area of Rivers State, Nigeria

“…This is in keeping with reports from other studies [19,29]. Fibrinogen plays a central role in coagulation [16] and correlates with inflammatory markers.…”

“…Inflammatory markers such as interleukin-6 (IL-6) [16] and in particular C-reactive protein (CRP) are considered risk factors for the metabolic syndrome [17] and cardiovascular disease [7]. Fibrinogen, an acute-phase reactant that also plays a central role in the coagulation cascade, has been linked to obesity in adults [18] and children [19].…”

Plasminogen activator inhibitor 1: Mechanisms of its synergistic regulation by growth factors

“…Obese patients, especially those with abdominal fat tissue distribution, have a high level of PAI-1 antigen and activity (Valle, Gascon et al 2000).…”