“…The results of the field efficacy test indicated that M. anisopliae formula can still live in the field, beside its presence in the field, is still able to control C. pavonana larvae until the 4 th day after application, both pellet formulations and flour formulations [14]. The results of bioassays of the suspension of M. anisopliase in tween 80 showed that from the day 3, M. anisopliase could produces mycotoxins, the amount of mycotoxins production was directly proportional to the growth period of the fungi, and optimal production occurs on day 7, these mycotoxins include myroridins, destruxins, hydroxyfungerins A dan B, metacytophilin, fusarin C, cytochalasins C and D [23]. Destruxin known to be the most abundant most abundant mycotoxins produced by Metharhizium, however, its virulence varies depend on the variety of species Metharhizium [24], Until now, destruxin, a mycotoxins from M. anisopliase is known to have insecticidal activity, destruxin can reduce insect immunity, however, its mode of action is not widely known [25].…”