Interventions for chronic suppurative otitis media

Acuin, Jose M; Smith, Andrew W.; Mackenzie, Ian C.

doi:10.1002/14651858.cd000473

Cited by 94 publications

(156 citation statements)

References 31 publications

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“…aluminium acetate, boric acid, iodine powder, and povidone-iodine are commonly used for CSOM because of their low cost and availability [81][82][83]. Eardrops containing antimicrobial agents either with or without an anti-inflammatory component have been promoted as an effective therapy for CSOM since the 1950s [84][85][86].…”

Section: Topical Treatmentmentioning

confidence: 99%

“…The effectiveness of ototopical drops was evaluated in a Cochrane Review [82]. CSOM was defined according to WHO criteria, i.e.…”

Section: Topical Treatmentmentioning

confidence: 99%

“…The overall quality of the studies included in these three reviews [82,89,[93][94][95][96][97], was generally considered low. The definition of CSOM, duration of discharge (3 weeks-40 years), age range of the patients (21 months-79 years) and follow-up varied considerably.…”

Section: Topical Treatmentmentioning

confidence: 99%

“…Potential ototoxicity of antibiotics, solvents, and antiseptics has been demonstrated in animal studies, but information regarding these adverse effects in humans is scarce [85]. In the studies reviewed by Acuin et al [82] negligible rates of ototoxicity were found.…”

Section: Topical Treatmentmentioning

confidence: 99%

“…However, no prospective, randomised, controlled trials justifying this guidance have been published [82]. Only three retrospective studies on surgical treatment for CSOM are available.…”

Section: Surgical Treatmentmentioning

confidence: 99%

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Chronic suppurative otitis media: A review

Verhoeff

Veen

Rovers

et al. 2006

International Journal of Pediatric Otorhinolaryngology

284

229

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Section: Topical Treatmentmentioning

confidence: 99%

“…The effectiveness of ototopical drops was evaluated in a Cochrane Review [82]. CSOM was defined according to WHO criteria, i.e.…”

Section: Topical Treatmentmentioning

confidence: 99%

Section: Topical Treatmentmentioning

confidence: 99%

Section: Topical Treatmentmentioning

confidence: 99%

“…However, no prospective, randomised, controlled trials justifying this guidance have been published [82]. Only three retrospective studies on surgical treatment for CSOM are available.…”

Section: Surgical Treatmentmentioning

confidence: 99%

See 3 more Smart Citations

Chronic suppurative otitis media: A review

Verhoeff

Veen

Rovers

et al. 2006

International Journal of Pediatric Otorhinolaryngology

284

229

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Predictors of Chronic Suppurative Otitis Media in Children

Veen

Schilder²,

Heerbeek³

et al. 2006

Arch Otolaryngol Head Neck Surg

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To determine which factors predict development of chronic suppurative otitis media (CSOM) in children. Design: Case-control study, with univariate and multivariate logistic regression analysis applied to determine which factors independently predict CSOM. Subjects: Prognostic factors for CSOM were identified in (1) 100 children with CSOM and 161 controls aged 1 to 12 years and (2) 83 children who developed CSOM in the presence of a tympanostomy tube and 136 children with tympanostomy tubes who did not develop CSOM. Results: Independent predictors for CSOM were previous tympanostomy tube insertion (odds ratio [OR], 121.4 [95% confidence interval {CI}, 38.9-379.3]); having had more than 3 upper respiratory tract infections in the past 6 months (OR, 12.2 [95% CI, 3.5-42.3]); having parents

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Estimated Monetary Value of Future Research Clarifying Uncertainties Around the Optimal Adult Hearing Screening Schedule

et al. 2022

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ImportanceAdult hearing screening is not routinely performed, and most individuals with hearing loss (HL) have never had their hearing tested as adults.ObjectiveTo project the monetary value of future research clarifying uncertainties around the optimal adult hearing screening schedule.Design, Setting, and ParticipantsIn this economic evaluation, a validated decision model of HL (DeciBHAL-US: Decision model of the Burden of Hearing loss Across the Lifespan) was used to simulate current detection and treatment of HL vs hearing screening schedules. Key model inputs included HL incidence (0.06%-10.42%/y), hearing aid uptake (0.54%-8.14%/y), screening effectiveness (1.62 × hearing aid uptake), utility benefits of hearing aids (+0.11), and hearing aid device costs ($3690). Distributions to model parameters for probabilistic uncertainty analysis were assigned. The expected value of perfect information (EVPI) and expected value of partial perfect information (EVPPI) using a willingness to pay of $100 000 per quality-adjusted life-year (QALY) was estimated. The EVPI and EVPPI estimate the upper bound of the dollar value of future research. This study was based on 40-year-old persons over their remaining lifetimes in a US primary care setting.ExposuresScreening schedules beginning at ages 45, 55, 65, and 75 years, and frequencies of every 1 or 5 years.Main Outcomes and MeasuresThe main outcomes were QALYs and costs (2020 US dollars) from a health system perspective.ResultsThe average incremental cost-effectiveness ratio for yearly screening beginning at ages 55 to 75 years ranged from $39 200 to $80 200/QALY. Yearly screening beginning at age 55 years was the optimal screening schedule in 38% of probabilistic uncertainty analysis simulations. The population EVPI, or value of reducing all uncertainty, was $8.2 to $12.6 billion varying with willingness to pay and the EVPPI, or value of reducing all screening effectiveness uncertainty, was $2.4 billion.Conclusions and RelevanceIn this economic evaluation of US adult hearing screening, large uncertainty around the optimal adult hearing screening schedule was identified. Future research on hearing screening has a high potential value so is likely justified.

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Interventions for chronic suppurative otitis media

Cited by 94 publications

References 31 publications

Chronic suppurative otitis media: A review

Chronic suppurative otitis media: A review

Predictors of Chronic Suppurative Otitis Media in Children

Estimated Monetary Value of Future Research Clarifying Uncertainties Around the Optimal Adult Hearing Screening Schedule

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