Intraocular pressure rise and recurrence of capsular block syndrome after neodymium:YAG laser anterior capsulotomy

Colakoglu, Ahmet; Kucukakyuz, Necmettin; Topcuoglu, Iffet E.; Akar, Solmaz

doi:10.1016/j.jcrs.2007.02.041

Cited by 17 publications

(12 citation statements)

References 6 publications

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“…Durak et al24 recommend performing anterior capsulotomy first, as this technique may be technically easier and safer than the posterior technique 24. Nevertheless, Colakoglu et al25 raised the issue of whether this approach is the best approach. These authors found a significantly lower success rate and higher recurrence rate among patients who underwent anterior capsulotomy compared with those who underwent posterior capsulotomy.…”

Section: Treatmentmentioning

confidence: 99%

Capsular block syndrome: a case report and literature review

Vélez¹,

Velásquez²,

Rojas³

et al. 2014

OPTH

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PurposeTo report the case of a patient who developed late capsular block syndrome and to review the current literature regarding this complication of phacoemulsification procedures.MethodsThe literature was reviewed to summarize the diagnosis, classification, use of diagnostic aids, and the current treatments for this complication.ResultsA 69-year-old patient complained of decreased visual acuity 11 months after undergoing phacoemulsification. She was found to have a secondary myopization. Anterior segment ultrabiomicroscopy confirmed the diagnosis of capsular block syndrome. The patient underwent neodymium-doped yttrium aluminum garnet (Nd:YAG) laser posterior capsulotomy, which resulted in complete resolution of her symptoms.ConclusionCapsular block syndrome is a fairly rare complication of phacoemulsification procedures that, depending primarily on the timing of its occurrence following surgery, can develop into one of the three following possible clinical scenarios: intraoperatory, early postoperatory, and late postoperatory. In this patient, Nd:YAG laser capsulotomy was shown to be a safe and effective treatment option for this type of complication.

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Section: Treatmentmentioning

confidence: 99%

Capsular block syndrome: a case report and literature review

Vélez¹,

Velásquez²,

Rojas³

et al. 2014

OPTH

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“…Colakoglu et al demonstrated that anterior laser capsulotomy would release opaque substance containing collagen and extracellular matrix into the anterior chamber that may be difficult to drain via anterior chamber angle resulting in uncontrollable IOP elevation. Meanwhile, milky-white fluid may reform soon after such procedure [22]. Koh et al surmised that LEC proliferation and anterior capsulotomy opening clogging may cause recurrence of late-onset CBS [23].…”

Section: Discussionmentioning

confidence: 99%

Outcome of Surgical Treatment in Late-Onset Capsular Block Syndrome

Huang

et al. 2017

Journal of Ophthalmology

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Purpose To further investigate the pathogenesis of late-onset capsular block syndrome (CBS) and to evaluate the safety of surgical treatment. Methods Seven patients diagnosed with late-onset CBS were retrospectively analyzed. Anterior chamber depth (ACD), intraocular pressure (IOP), refractive diopter, and best-corrected visual acuity (BCVA) before and after surgery were recorded. The opaque substance was tested with Western blot, and a flow cytometer multiple array assay system was utilized to evaluate the levels of inflammatory cytokines from opaque substance and aqueous humor, respectively. Results Patients who had undergone surgical treatment showed a significant BCVA and spherical equivalent refractive error improvement (P = 0.002, P = 0.021, resp.). Nevertheless, ACD and IOP before and after surgery were in normal range with no difference (P = 0.165, P = 0.749, resp.). αB-crystallin and βB-crystallin were detected in all opaque substances. Tumor necrosis factor-alpha (TNF-α) and interlukin-1β (IL-1β) levels in opaque substance were significantly higher than those in aqueous humor (P = 0.038, P = 0.007, resp.), while IL-2 and IL-6 were not detected in any samples. Conclusions Opaque substance is derived from human lens epithelial cells. Inflammatory cytokines may be involved in the pathogenesis of late-onset CBS. In addition, surgical treatment is an effective approach. This trial is registered with ChiCTR-IOR-17011287.

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“…13 Colakoglu et al 13 report that the milkywhite fluid may reform soon after anterior capsulotomy in cases of late CBS without posterior capsulotomy. In our series, Nd:YAG capsulotomy treatment failed in 3 cases and 1 patient chose drainage surgery based on the risk for increased IOP and liquid reformation after Nd:YAG capsulotomy.…”

Section: Discussionmentioning

confidence: 99%