Investigation of Melatonin Content and Antioxidant Capacity in Grape Berries

Yılmaz, Uğur

doi:10.33715/inonusaglik.987625

Cited by 6 publications

(2 citation statements)

References 32 publications

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“…Melatonin, a hormone primarily associated with regulating sleep–wake cycles, has been identified in various plant sources, including goji berries. Studies have shown that goji berries contain significant levels of melatonin, although the exact concentration may vary depending on factors such as growing conditions, maturity at harvest, and post-harvest handling [ 116 ].…”

Section: Bioactive Composition Of L Barbarummentioning

confidence: 99%

Antitumor Mechanisms of Lycium barbarum Fruit: An Overview of In Vitro and In Vivo Potential

Miranda,

Vestuto,

Amodio

et al. 2024

Life

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Lycium barbarum, known as goji berry or wolfberry, is a fruit long associated with health benefits, showing a plethora of effects ranging from antioxidant, anticancer, anti-inflammatory, and immunomodulatory effects. Its potential is attributed to the significant presence of polysaccharides, glycopeptides, polyphenols, flavonoids, carotenoids, and their derivatives. These compounds effectively counteract the action of free radicals, positively influencing cellular balance and intracellular signaling, contributing to overall cell health and function acting on multiple molecular pathways. Several fractions extracted from goji berries demonstrate antitumor properties, particularly effective against breast cancer, without showing cytotoxic effects on normal human cells. Hence, the review explored the fundamental traits of bioactive elements in Lycium barbarum and their potential in cancer treatment and, specifically, breast cancer. It focused on elucidating wolfberry’s influenced biochemical pathways, its synergism with anticancer drugs, and its potential to alleviate the side effects associated with existing cancer treatments.

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Section: Bioactive Composition Of L Barbarummentioning

confidence: 99%

Antitumor Mechanisms of Lycium barbarum Fruit: An Overview of In Vitro and In Vivo Potential

Miranda,

Vestuto,

Amodio

et al. 2024

Life

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“…2 Tanaman murbei memiliki kandungan antioksidan yang baik untuk kesehatan pada buah dan daunnya. 3,4 Selain itu, bahan aktif daun murbei dapat digunakan untuk mengobati beberapa penyakit, seperti hipertensi, diabetes, hiperlipidemia, dan sebagai imunomodulasi. 5 Pengembangan dan penelitian berbasis tanaman ini sangat diperlukan karena sumber bahan alamnya tersedia banyak diwilayah Indonesia.…”

Section: Pendahuluanunclassified

Identifikasi Senyawa Kimia Pada Ekstrak Daun Murbei (Morus ALBA.L)

Purnama

2022

SPICM

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Nutrisi yang alami khususnya tadabbur dari Al-Qur’an dan Sunnah perlu diulas secara ilmiah. Salah satu contoh adalah tanaman murbei (Morus Alba L). Tanaman murbei memiliki kandungan antioksidan yang baik untuk kesehatan pada buah dan daunnya. Penelitian ini bertujuan untuk mengindentifikasi senyawa kimia dalam daun murbei dengan analisis secara kualitatif. Hasil penelitian kami menunjukkan bahwa kandungan ekstrak methanol daun murbei mengandung senyawa alkaloid, flavonoid, saponin, tannin dan terpenoid. Hal tersebut dibuktikan dengan adanya perubahan warna pada setiap sampel yang diberikan pereaksi tertentu. Daun murbei terbukti memiliki senyawa antioksidan yang baik untuk tubuh.

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Relationship Between Phenolic Content Determined by LC/MS/MS and Antioxidant Capacity and Enzyme Inhibition of Cyclotrichium niveum L.

Güzel

2023

Chemistry & Biodiversity

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Cyclotrichium niveum (Boiss.) Manden & Scheng belonging to the Lamiaceae family, which is an endemic species in the eastern Anatolian region of Turkey, has an important place in terms of ethno-botany. The phytochemical composition of the plant, inhibition of acetylcholinesterase (AChE) (which hydrolyzes the neurotransmitter acetylcholine), inhibition of paraoxonase for antiatherosclerotic activity (hPON 1) (which detoxifies organophosphates), and antioxidant capacity were all investigated in this study. Phytochemical content was determined by LC/MS/MS, and enzyme inhibition and antioxidant capacity studies were determined by spectrophotometer. Antioxidant capacity of C. niveum extracts (methanol, hexane, and water) was determined by applying ABTS * + , DPPH * , FRAP, and CUPRAC methods. Both the water and the methanol extracts of the C. niveum exhibited significant inhibition on the AChE (IC 50 value for methanol and water extract 0.114 � 0.14 mg/ mL (R2:0.997) and 0.178 � 0.12 mg/mL (R 2 : 0.994), respectively). In contrast, the methanol and water extracts of the C. niveum did not exhibit the inhibition effect on hPON 1. The highest activity for ABTS * + was 66.53 % in the water extract, and DPPH * was 55.03 % in the methanol extract. In the metal-reducing power assay, the absorbance was 0.168 � 0.04 for FRAP water extract and 0.621 � 0.01 for CUPRAC methanol extract. According to LC/MS/MS analyses, hydroxybenzoic acid, salicylic acid, syringic acid, acetohydroxamic acid and luteolin determined in the plant extract. As a consequence, C. niveum which has antioxidant, anti-atherogenic and antineurodegenerative properties has the potential to be used as a natural medication instead of synthetic drugs used in Alzheimer's patients.

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Investigation of Melatonin Content and Antioxidant Capacity in Grape Berries

Cited by 6 publications

References 32 publications

Antitumor Mechanisms of Lycium barbarum Fruit: An Overview of In Vitro and In Vivo Potential

Antitumor Mechanisms of Lycium barbarum Fruit: An Overview of In Vitro and In Vivo Potential

Identifikasi Senyawa Kimia Pada Ekstrak Daun Murbei (Morus ALBA.L)

Relationship Between Phenolic Content Determined by LC/MS/MS and Antioxidant Capacity and Enzyme Inhibition of Cyclotrichium niveum L.

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