Investigation on the thermo-mechanical properties and thermal stability of polylactic acid tissue engineering scaffold material

Wang, Fang; Guo, Gepu; Ma, Qingyu; Gu, Minfeng; Wu, XuYing; Sheng, Shenjun; Wang, Xiaoshu

doi:10.1007/s10973-013-3221-1

Cited by 18 publications

(10 citation statements)

References 26 publications

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“…Thus, foams of smaller cell size exhibited higher activation energy and longer conversion time at constant heating rate, as also reported by Wang et al. [ 307 ]…”

Section: Degradation Studies Of Biodegradable Foamssupporting

confidence: 79%

Foamability and Special Applications of Microcellular Thermoplastic Polymers: A Review on Recent Advances and Future Direction

Banerjee¹,

Ray

2020

Macro Materials & Eng

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Figure 6. a) Schematic of underwater pelletization as a following unit of a foam extrusion system. For expandable beads, the water pressure is set above the vapor pressure of the blowing agent; for expanded, it lies at atmospheric pressure. b) Bead foam processing in a steam-chest molding machine: 1: closing and 2: filling the mold, 3: steaming, 4: cooling, 5: ejection of molded part. Reproduced with permission. [53] Copyright 2015, Elsevier.

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“…Thus, foams of smaller cell size exhibited higher activation energy and longer conversion time at constant heating rate, as also reported by Wang et al. [ 307 ]…”

Section: Degradation Studies Of Biodegradable Foamssupporting

confidence: 79%

Foamability and Special Applications of Microcellular Thermoplastic Polymers: A Review on Recent Advances and Future Direction

Banerjee¹,

Ray

2020

Macro Materials & Eng

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“…Increase of fiber proportion in fiber‐reinforced PLA was said to lower the permeability of volatile degradation products, which further extended the thermal degradation process. [ 225–227 ] Gunti et al, [ 201 ] reported that initial degradation occurred at 322°C for neat PLA. Most degradation occurred in the temperature range of 322 to 430°C and the char residues after combustion were 0.3%.…”

Section: Fiber‐reinforced Plamentioning

confidence: 99%

Flame retardancy and thermal stability of agricultural residue fiber‐reinforced polylactic acid: A Review

et al. 2020

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Biocomposites containing natural fibers and biopolymers are an ideal choice for developing substantially biodegradable materials for different applications. Polylactic acid is a biopolymer produced from renewable resources and has drawn numerous interest in packaging, electrical, and automotive application in recent years. However, its potential application in both electrical and automotive industries is limited by its flame retardancy and thermal properties. One way to offset this challenge has been to incorporate natural or synthetic flame retardants in polylactic acid (PLA). The aim of this article is to review the trends in research and development of composites based on agricultural fibers and PLA biopolymers over the past decade. This article highlights recent advances in the fields of flame retardancy and thermal stability of agricultural fiber‐reinforced PLA. Typical fiber‐reinforced PLA processing techniques are mentioned. Over 75% of the studies reported that incorporation of agricultural fibers resulted in enhanced flame retardancy and thermal stability of fiber‐reinforced PLA. These properties are further enhanced with surface modifications on the agricultural fibers prior to use as reinforcement in fiber‐reinforced PLA. From this review it is clear that flame retardancy and thermal stability depends on the type and pretreatment method of the agricultural fibers used in developing fiber‐reinforced PLA. Further research and development is encouraged on the enhancement of the flame retardancy properties of agricultural fiber‐reinforced PLA, especially using agricultural fibers themselves as flame retardants as opposed to synthetic flame retardants that are typically used.

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“…Synthetic biomaterials such as polycaprolactone [ 4 ], polyvinyl alcohol [ 5 ], and polylactic acid [ 6 ] have well-defined mechanical and rheological properties and transport of molecules by modulating degree of substitution and crosslinking density [ 7 ]. However, these materials are inert and lack biological cues that can promote cell adhesion, proliferation, and chondrogenic differentiation.…”

Section: Introductionmentioning

confidence: 99%

Carboxymethyl Cellulose Entrapped in a Poly(vinyl) Alcohol Network: Plant-Based Scaffolds for Cartilage Tissue Engineering

et al. 2021

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Cartilage has a limited inherent healing capacity after injury, due to a lack of direct blood supply and low cell density. Tissue engineering in conjunction with biomaterials holds promise for generating cartilage substitutes that withstand stress in joints. A major challenge of tissue substitution is creating a functional framework to support cartilage tissue formation. Polyvinyl alcohol (PVA) was crosslinked with glutaraldehyde (GA), by varying the mole ratios of GA/PVA in the presence of different amounts of plant-derived carboxymethyl cellulose (CMC). Porous scaffolds were created by the freeze-drying technique. The goal of this study was to investigate how CMC incorporation and crosslinking density might affect scaffold pore formation, swelling behaviors, mechanical properties, and potential use for engineered cartilage. The peak at 1599 cm−1 of the C=O group in ATR–FTIR indicates the incorporation of CMC into the scaffold. The glass transition temperature (Tg) and Young’s modulus were lower in the PVA/CMC scaffold, as compared to the PVA control scaffold. The addition of CMC modulates the pore architecture and increases the swelling ratio of scaffolds. The toxicity of the scaffolds and cell attachment were tested. The results suggest that PVA/CMC scaffolding material can be tailored in terms of its physical and swelling properties to potentially support cartilage formation.

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Investigation on the thermo-mechanical properties and thermal stability of polylactic acid tissue engineering scaffold material

Cited by 18 publications

References 26 publications

Foamability and Special Applications of Microcellular Thermoplastic Polymers: A Review on Recent Advances and Future Direction

Foamability and Special Applications of Microcellular Thermoplastic Polymers: A Review on Recent Advances and Future Direction

Flame retardancy and thermal stability of agricultural residue fiber‐reinforced polylactic acid: A Review

Carboxymethyl Cellulose Entrapped in a Poly(vinyl) Alcohol Network: Plant-Based Scaffolds for Cartilage Tissue Engineering

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