Isolation and Identification of the Causative Agent in Epidemic Keratoconjunctivitis (Superficial Punctate Keratitis) and Herpetic Keratoconjunctivitis*

Maumenee, A. Edward; Hayes, Guy S.; Hartman, Thomas L.

doi:10.1016/s0002-9394(45)90112-7

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1997

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Cited by 31 publications

(3 citation statements)

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“…* Epidemiologic investigation. Using the case definitions described in the Material and Methods section, 34 nosocomial and 103 communityacquired cases of EKC were identified by the ICC and DHMH. Fifteen nosocomial cases were found to be related to exposure in the emergency department and 19 were related to exposure in the resident clinic.…”

Section: Employee Furloughsmentioning

confidence: 99%

Surveillance and control of epidemic keratoconjunctivitis

Gottsch¹

1997

American Journal of Ophthalmology

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Section: Employee Furloughsmentioning

confidence: 99%

Surveillance and control of epidemic keratoconjunctivitis

Gottsch¹

1997

American Journal of Ophthalmology

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“…Maumenee et al (1945) reported isolation of herpes simplex virus from a patient with bilateral keratoconjunctivitis with no evidence of dendritic ulcers or facial herpetic lesions. Jawetz et al (1955) isolated herpes simplex virus in 2 patients with acute keratoconjunctivitis.…”

Section: Symptoms and Signsmentioning

confidence: 99%

Acute follicular conjunctivitis and keratoconjunctivitis due to herpes simplex virus in London.

Darougar¹,

Hunter²,

Viswalingam³

et al. 1978

British Journal of Ophthalmology

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This report presents the findings in 25 cases of acute herpetic follicular conjunctivitis which presented without characteristic lid, face, or corneal signs of herpetic infections. In most of them, the correct diagnosis could be made only by cultural or serological tests for HSV infection. Methods and patientsPatients with acute follicular conjunctivitis or keratoconjunctivitis without facial, lid, or corneal lesions typical of HSV infection at the first visit, but with positive cultural or serological tests for HSV, were included.The patients were examined with a Haag-Streit

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“…

It has been shown by virus isolation, serologic and human volunteer experiments that epidemic keratoconjunctivitis (EKC) is caused by adenovirus Type 8.In the acute conjunctivitis stage of EKC, characteristic inclu sion bodies can be seen in the cytoplasm of conjunctival epithelial cells (Wriyht, 1930; Zur Ncdden, 1938;Maumenee et al, 1945; SieBoen-Lian, 1948, 1962Silva, 1948;Lepri, 1952; Hofmann, 1955;Imre et al, 1963, and Necsei, 1963). The nature of the inclusion bodies is not clear; they may correspond to aggregates of virus particles of metabolic products formed by the interaction of virus and host cell.

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confidence: 99%