1966
DOI: 10.1002/1097-0142(196604)19:4<557::aid-cncr2820190415>3.0.co;2-3
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Kaposi's sarcoma.Management with vincaleucoblastine

Abstract: The successful management of Kaposi's sarcoma with a systemic chemotherapeutic agent, Vincaleucoblastine, is presented. All patients, including the initial case treated in 1961, are presently free from disease. This method of treatment could be of considerable value in Central Africa, where the incidence is greater and facilities for radiotherapy and perfusion less.

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Cited by 31 publications
(2 citation statements)
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“…Cook treated six cases by intraarterial perfusion of nitrogen mustard and reported a complete regression that endured for nearly two years in one case and improvement that endured for more than one‐half year in three cases. Scott and Voight treated three patients with vinblastine and effected shrinkage of tumid lesions and short‐term palliation of symptoms . On the brighter side, Cohen treated 58 patients between 1949 and 1960 by radiotherapy limited to grossly visible lesions in doses that varied from a single exposure of 1,000 rads to 2,500 rads in divided doses over four weeks, and reported disappearance of those lesions in 36 of 65 sites treated.…”
Section: Review Of the Literaturementioning
confidence: 99%
“…Cook treated six cases by intraarterial perfusion of nitrogen mustard and reported a complete regression that endured for nearly two years in one case and improvement that endured for more than one‐half year in three cases. Scott and Voight treated three patients with vinblastine and effected shrinkage of tumid lesions and short‐term palliation of symptoms . On the brighter side, Cohen treated 58 patients between 1949 and 1960 by radiotherapy limited to grossly visible lesions in doses that varied from a single exposure of 1,000 rads to 2,500 rads in divided doses over four weeks, and reported disappearance of those lesions in 36 of 65 sites treated.…”
Section: Review Of the Literaturementioning
confidence: 99%
“…Άλλος χηµειοθεραπευτικός παράγοντας που χρησιµοποιείται για τη θεραπεία του κλασικού ΚΣ είναι η πεγκυλιοµένη λιποσωµιακή δοξορουβικίνη (pegylated liposomal doxorubicin) µε καλά αποτελέσµατα (71% ανταπόκριση σε 55 ασθενείς). [132][133][134][135] Έχουν γίνει πολλές έρευνες για την ένταξη και άλλων φαρµάκων µε ενδοφλέβια, per os αλλά και τοπική χορήγηση. Σε µια µελέτη δοκιµάστικε η βινκριστίνη (vincristine ) σε έναν άρρωστο ενέσιµα εντός της βλάβης µε δόση 0,25 έως 0,50 mg. Το αποτέλεσµα ήταν η πλήρης εξαφάνιση της δερµατικής βλάβης.…”
Section: κλασικό κςunclassified