Karakteristik Fisik dan Aktivitas Antibakteri Sabun Cair Minyak Nilam (Pogostemon cablin Benth.) yang Berbasis Surfaktan Sodium Lauril Eter Sulfat

Anggraeni, Yuni; Nisa, Fakhrun; Betha, Ofa Suzanti

doi:10.22435/jki.v10i1.499

Cited by 8 publications

(7 citation statements)

References 3 publications

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“…HPMC is a cellulose derivative that stabilizes foam through gelatinization in addition to its main function as a thickening agent. The HPMC polymer structure strengthens the walls of the foam bubbles and slows the flow of water; hence, the foam becomes denser and more stable (Anggraeni et al, 2020). The formula with the largest amount and highest foam stability was F3, which contained an extract concentration of 5%.…”

Section: Resultsmentioning

confidence: 99%

LIQUID SOAP FORMULATION FROM ETHANOLIC EXTRACT OF CASSAVA LEAVES (Manihot esculenta Crantz) WITH COCAMIDE DEA AS SURFACTANT

Martihandini,

Putria Angelica,

Isasi Sutiswa

2024

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The ethanol extract of cassava leaves contains various secondary metabolites that have antibacterial activity against Escherichia coli, Staphylococcus aureus, and Shigella sp., and thus can be used as active ingredients in liquid soap preparation. Liquid soap formulations generally use sodium lauryl sulfate (SLS) as a surfactant, which can cause irritation and skin dryness. This study aimed to formulate an ethanol extract from cassava leaves into a liquid soap preparation using cocamide DEA as a surfactant to reduce skin irritation. The study was conducted in an experimental laboratory. Cassava leaves were extracted by maceration using ethanol. Three liquid soap formulas from cassava leaf extract were developed with different extract concentrations: F1 (1%), F2 (3%), and F3 (5%). The liquid soaps were evaluated in terms of organoleptic properties, pH, homogeneity, viscosity, foam height, and foam stability. The study showed that cassava leaves extract could be formulated into a homogeneous liquid soap with a pH range of 7.0–7.5, viscosity of 143.6–306.2 cps, foam height of 53.33–60.00 mm, and foam stability of 75.01–82.36%. F3 is the optimum formula with the best physical characteristics of the preparation in terms of organoleptic properties, foam height, and foam stability. Keywords: cocamide DEA, cassava leaves, liquid soap, surfactant

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Section: Resultsmentioning

confidence: 99%

LIQUID SOAP FORMULATION FROM ETHANOLIC EXTRACT OF CASSAVA LEAVES (Manihot esculenta Crantz) WITH COCAMIDE DEA AS SURFACTANT

Martihandini,

Putria Angelica,

Isasi Sutiswa

2024

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“…The use of surfactant is based on the suitability of the HLB value needed to form a stable and not easily broken emultion. Anggraeni et al, (2020) stated that the ability of an antimicrobial agent to eliminate the viability of microorganisms depends on the concentration of the antimicrobial agent. By the observations, it was found that the average diameter of the inhibition zone was getting bigger as the concentration of patchouli oil was added.…”

Section: Resultsmentioning

confidence: 99%

Formulation of patchouli oil spray gel (Pogostemon cablin Benth) and irritation test in rabbit

et al. 2023

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Patchouli plant (Pogostemon cablin Benth) is one of the essential oil-producing plants widely used in perfume, cosmetic, aromatherapy, antiseptic, antibacterial, and antifungal industries. The essential oil derived from patchouli leaves contains terpenoid compounds with antibacterial and antifungal activity. This study aims to determine the optimum formulation of patchouli oil spray gel as a wound antiseptic and to observe the irritation test of the samples. The spray gel formulations of patchouli oil were prepared in various concentrations i.e. 5%, 7.5%, and 10% (v/v), solved in aquadest with the addition of carbopol 940 as the gelating agent. The spray gels were tested to determine their physical characteristics, including the organoleptic test, homogeneity test, pH, adhesive dispersion test, viscosity test, and spray pattern test. The results showed that the patchouli oil spray gels were yellowish-white and had a distinctive odor and homogeneous texture with a pH 5. They all had adhesive dispersion, and the optimum viscosity of the spray gel was found at a 7.5% (v/v) concentration of patchouli oil. The irritation test was carried out using the patch test method with a score of erythema and edema. The results showed that all three formulas very mild irritation.

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“…Uji viskositas akan berpengaruh terhadap pengaplikasian saat digunakan oleh konsumen seperti mudah dituang dan tidak mudah tumpah (10). Oleh karena itu, viskositas dapat berpengaruh terhadap tingkat presepsi pemakaian masyarakat terkait penerimaan produk.…”

Section: Tabel 4 Uji Viskositasunclassified

Formulasi Basis Sabun Cair sebagai Metode Penghantaran Sediaan Antiseptik

Johan

Darma

Aryani

2022

BCSP

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Abstract. Most people use liquid soap as a cleanser in their daily lives. Chemicals known as antiseptics are used to stop or eliminate bacteria from growing on living tissues, thus preventing skin infections. By preventing the growth of bacteria, antiseptic liquid soap lowers the risk of infection and the development of diseases. Flavonoids and polyphenols are active substances and have antibacterial properties. A preparation called antiseptic liquid soap is used to clean the skin's surface of debris and bacteria. Its objectives are to determine the liquid soap formula that satisfies the requirements and to ascertain the liquid soap's antibacterial activity toward the germs Escherichia coli and Staphylococcus aureus. The method carried out is the evaluation of the soap base and the test of antibacterial activity on the soap base. In formula 3 in accordance with SNI 2017, which is in the form of a homogeneous liquid, different aromas, pH 8.98, viscosity 2570 cPs, type weight 1.042, foam stability 69.5%, free fatty acids 0.20%, and alkali-free 0.096%, and has antibacterial activity with a strong category, namely Escherichia 19.37 mm and Staphylococcus aureus 20.15 mm. Abstrak. Sabun cair adalah sediaan pembersih yang cukup banyak digunakan dalam kehidupan sehari-hari. Antiseptik adalah senyawa kimia yang digunakan untuk menghambat atau membunuh mikroorganisme pada jaringan hidup, serta dapat mencegah infeksi kulit. Sabun cair antiseptik berfungsi untuk menghambat pertumbuhan bakteri dan mengurangi resiko infeksi serta timbulnya penyakit. Senyawa aktif yang mempunyai aktivitas antibakteri yaitu flavonoid dan polifenol. Sabun cair antiseptik berfungsi sebagai sediaan yang dapat menghilangkan kotoran dan mikroorganisme pada permukaan kulit. Tujuannya adalah untuk mengetahui formula basis sabun cair yang memenuhi persyaratan dan untuk mengetahui aktivitas antibakteri terhadap bakteri Escherichia coli dan Staphylococcus aureus dalam basis sabun cair. Metode yang dilakukan yaitu evaluasi basis sabun dan uji aktivitas antibakteri pada basis sabun. Pada pembuatan sediaan sabun cair formula 3 dengan menghasilkan evaluasi yang sesuai dengan SNI 2017 yaitu berbentuk cairan yang homogen, berbau khas, pH 8,98, viskositas 2570 cPs, bobot jenis 1,042, stabilitas busa 69,5%, asam lemak bebas 0,20% dan alkali bebas 0,096% serta memiliki aktivitas antibakteri dengan kategori kuat yaitu Escherichia coli 19,37 mm dan Staphylococcus aureus 20,15 mm.

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Karakteristik Fisik dan Aktivitas Antibakteri Sabun Cair Minyak Nilam (Pogostemon cablin Benth.) yang Berbasis Surfaktan Sodium Lauril Eter Sulfat

Cited by 8 publications

References 3 publications

LIQUID SOAP FORMULATION FROM ETHANOLIC EXTRACT OF CASSAVA LEAVES (Manihot esculenta Crantz) WITH COCAMIDE DEA AS SURFACTANT

LIQUID SOAP FORMULATION FROM ETHANOLIC EXTRACT OF CASSAVA LEAVES (Manihot esculenta Crantz) WITH COCAMIDE DEA AS SURFACTANT

Formulation of patchouli oil spray gel (Pogostemon cablin Benth) and irritation test in rabbit

Formulasi Basis Sabun Cair sebagai Metode Penghantaran Sediaan Antiseptik

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