Kejadian Tuberkulosis Multi Drug Resistant di RSUP dr. Kariadi

Triandari, Devi; Rahayu, Sri

doi:10.15294/higeia.v2i2.19388

Cited by 4 publications

(4 citation statements)

References 7 publications

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“…Current study showed the most dominant determinants of drug-resistant PTB were the history of previous treatment and AFB gradation. These findings consistent and similarly with previous studies [11][12][13][14], while the recent study in Dr. Kariadi General Hospital showed that previous treatment was not the determinant of drug-resistant PTB [9]. The current study confirmed well-known common knowledge of the determinants for drug-resistant PTB.…”

Section: And Figsupporting

confidence: 93%

“…This finding also have been proved by previous study in Dr. Kariadi General Hospital as the most dominat factor that related to the MDR-TB cases. Patients with duration of treatment more than 7 months had 3.23 times higher risk to be resistant [9]. Based on bivariate analysis, current study also concluded that patients with duration of treatment more than 6 months would have 6.9 times higher risk to get drug-resistant PTB case as shown in Table II.…”

Section: And Figmentioning

confidence: 50%

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Determinants of Drug-resistant Pulmonary Tuberculosis in Dr. Kariadi General Hospital, Indonesia

Azam¹,

Yulia²,

Saefurrohim³

et al. 2019

Proceedings of the 5th International Conference on Physical Education, Sport, and Health (ACPES 2019)

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Indonesia ranked 6th from countries with the highest burden of drug-resistant pulmonary tuberculosis (PTB). A rate of 1.9% of new cases develop to be resistant and even 12% from previous treated cases. Previous studies concluded determinants of drug-resistant PTB, however, the study in Indonesia, especially in the scope of hospitals is still limited. Our study aims to explore the determinant of drug-resistant PTB in Dr. Kariadi General Hospital. We conducted a case-control study, using data from medical records. A sample of 76 cases and 76 controls have met the criterion and were involved in the study. The status of drug-resistant cases determined by rapid molecular test. We observed the subject's characteristics and determinants of drug-resistant PTB. Study shows that there is no significant difference in the subject's characteristics, i.e. age, sex, level of education, and working status between the group of cases and controls. Chi-square analysis shows that history of previous treatment, HIV infection, drug side-effects status, Acid-Fast Bacilli (AFB) gradation, and duration of treatment were related to drug-resistant pulmonary TB. After conducted Binary Logistic Regression, we concluded that history of treatment (OR=24.3; 95%CI: 8.49-69.33) and AFB gradation (OR=13.8; 95% CI: 2.76-68.60) altogether as dominant determinants of drug-resistant PTB.

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Section: And Figsupporting

confidence: 93%

Section: And Figmentioning

confidence: 50%

Determinants of Drug-resistant Pulmonary Tuberculosis in Dr. Kariadi General Hospital, Indonesia

Azam¹,

Yulia²,

Saefurrohim³

et al. 2019

Proceedings of the 5th International Conference on Physical Education, Sport, and Health (ACPES 2019)

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“…Riwayat pengobatan TB sebelumnya paling dominan berhubungan dengan kejadian MDR. Riwayat pengobatan TB gagal dan putus berobat merupakan faktor terjadinya TB MDR 5 . Hal yang sama juga dibuktikan dengan penelitian lain yaitu riwayat pengobatan TB berhubungan dengan kejadian MDR TB 6 .…”

Section: Pendahuluanunclassified

Riwayat Pengobatan dan Komorbid Diabetes Mellitus Berhubungan Dengan Kejadian Tuberkulosis Resisten Obat

Manggasa

Suharto

2022

JIK

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Tujuan penelitian untuk menganalisis hubungan antara riwayat pengobatan Tuberkulosis (TB) sebelumnya dan komorbid Diabetes Mellitus (DM) dengan kejadian Tuberkulosis Resisten Obat (TB RO) di Kabupaten Poso. Metode penelitian yaitu observasional analitik dengan desain studi case control. Populasi yaitu seluruh pasien penderita TB di Kabupaten Poso. Sampel yaitu 32 pasien TB RO sebagai kelompok kasus dan 32 penderita TB Sensitifi Obat (TB SO) sebagai kelompok kontrol. Pengambilan data dengan mengidentifikasi data Sistem Informasi Tuberkulosis (SITB). Analisis statistik menggunakan uji chi Square. Hasil penelitian menunjukkan pasien TB yang pernah menjalani pengobatan sebelumnya yaitu TB RO sebesar 65,5% dan TB SO sebesar 18,8%, dengan nilai p = 0,000, pasien TB yang tidak teratur minum obat yaitu TB RO sebesar 71,9% dan TB SO sebesar 15,6% dengan nilai p = 0,000, pasien TB yang menderita komorbid DM yaitu TB RO sebesar 31,3% dan TB SO sebesar 6,3% dengan nilai p = 0,025. Kesimpulan terdapat hubungan antara riwayat pengobatan sebelumnya dan adanya komorbid DM dengan kejadian TB RO pada pasien TB di Kabupaten Poso. Saran agar fasilitas pelayanan kesehatan meningkatkan manajemen program layanan TB untuk menjamin keteraturan minum obat sehingga mencegah terjadinya TB RO.

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“…Penelitian Triandari menyatakan terdapat hubungan antara pendapatan seseorang dengan kejadian MDR-TB. 28 Pendapatan yang rendah berisiko 3 kali untuk menjadi MDR-TB. 29 Seseorang dengan pendapatan rendah akan sulit untuk memenuhi kebutuhan gizi keluarganya sehingga akan berdampak terhadap kesehatannya.…”

Section: Pembahasan Karakteristik Subjek Penelitianunclassified

Gambaran Riwayat Pengobatan Tuberkulosis pada Pasien Multi Drug Resistant Tuberculosis di RSUP Dr. M. Djamil Padang

Annisatuzzakiyah¹,

Bahar

Putri

2021

JIKESI

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Background. The incidence of MDR-TB becomes a health issue that must be addressed immediately. According to a 2014 WHO report, the incidence of deaths from MDR-TB reached 190,000 cases. In 2015 there were 250,000 deaths and in 2016 there were 240,000 deaths. The incidence of MDR-TB cases in Indonesia has been reported in 2013 reaching 1,094 cases. In 2014 there were 1,752 cases and in 2015 there were 1,860. MDR-TB events can occur due to failure in the treatment of previous TB. Objective. This research aim to know overview of tuberculosis treatment history in patient with multy drug resistant (MDR-TB) in RSUP Dr. M. Djamil Padang Methods.This research an descriptive study with cros sectional designed, based on medical record of MDR-TB patient in RSUP Dr. M. Djamil Padang in 2018-2019, a sample of 37 people sample using total sampling and it was analyzed by univariate analysis. Result. The result of this research showed the characteristics of MDR-TB were found most in the age group of 35-44 years(27%), male gender (64,9%), self imployed (35,1%). with the most history of treatment in the form of relapsing cases (32,4%). Conclusion. the conclusion of this study is the patient with MR-TB in RSUP Dr. M. Djamil Padang dominated by age of 35-44 years old, male and self imployed and the history of TB treatment in MDR-TB patients founnd the most cases of relaps

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Kejadian Tuberkulosis Multi Drug Resistant di RSUP dr. Kariadi

Cited by 4 publications

References 7 publications

Determinants of Drug-resistant Pulmonary Tuberculosis in Dr. Kariadi General Hospital, Indonesia

Determinants of Drug-resistant Pulmonary Tuberculosis in Dr. Kariadi General Hospital, Indonesia

Riwayat Pengobatan dan Komorbid Diabetes Mellitus Berhubungan Dengan Kejadian Tuberkulosis Resisten Obat

Gambaran Riwayat Pengobatan Tuberkulosis pada Pasien Multi Drug Resistant Tuberculosis di RSUP Dr. M. Djamil Padang

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