Leiomyosarcoma of the Spermatic Cord in a Seventy-Five-Year-Old man

Dehghan, Arash; Sami, Ghazal; Eskandari, Nika

doi:10.5812/numonthly.24308

Cited by 3 publications

(4 citation statements)

References 9 publications

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“…Intimate pathophysiologic mechanisms that lead to the occurrence of these neoplasms are unknown, although it is speculated with the role that could play an occasional degeneration of a leiomyoma originated prior from funicular structures constructed by smooth-muscle. 1 , 2 …”

Section: Discussionmentioning

confidence: 99%

Spermatic Cord Leiomyosarcoma Rare Case

Frigerio

Muruato-Araiza

Marcos-Morales

et al. 2016

Urology Case Reports

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Case description of a male patient of 64 years who presents a left groin-scrotum painless tumor, growing, from several months of evolution. Physical examination demonstrated the existence of a mass effect of the left distal spermatic cord, and was later confirmed by ultrasound and CT. Laboratory parameters were normal. The performed surgery consisted in a radical orchiectomy with high ligation of the left cord. In conclusion, preoperative diagnosis of spermatic cord leiomyosarcoma is difficult we need the combination of present illness, physical examination, exams and the gold standard histopathological and immunohistochemical studies allowed a definitive diagnosis.

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Section: Discussionmentioning

confidence: 99%

Spermatic Cord Leiomyosarcoma Rare Case

Frigerio

Muruato-Araiza

Marcos-Morales

et al. 2016

Urology Case Reports

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“…Only about 115 cases of spermatic cord leiomyosarcoma have been reported in the world literature, and only about 43 cases in the English literature. [4][5][6][7][8][9] Thus, the present case seems important, because the present case adds a case in the lists of spermatic cord leiomyosarcoma. Immunohistochemically, the present tumor was positive for vimentin, α-smooth muscle actin, h-caldesmon, desmin (focal), p53, and Ki-67 antigen (labeling = 34%), but negative for pancytokeratin AE1/3, pancytokeratin CAM5.2, KIT (CD117), CD34, S100 protein, and myoglobin.…”

Section: Discussionmentioning

confidence: 99%

“…The most recent study also reported that there are only about 115 cases of leiomyosarcoma of the spermatic cord in the world literature. [4][5][6][7] This pathological entity in spermatic cord was first reported by Wessel in 1953. [8] All of these reported cases of leiomyosarcoma in spermatic cord are case reports, and there have been no comprehensive studies using many cases.…”

Section: Introductionmentioning

confidence: 99%

Leiomyosarcoma of the spermatic cord

Terada

2016

CRCP

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Leiomyosarcoma of spermatic cord is very rare. The patient is 65-year-old man who presented with a tumor in scrotum. Excision of tumor was performed and it showed a solid tumor measuring 4 cm × 3 cm × 3 cm in left spermatic cord. Histologically, it showed proliferation of hypercellular atypical spindle cells with hyperchromatic nuclei. The tumor cells were arranged with fascicles of cigar-shaped spindled cells with scant acidophilic cytoplasm. The tumor was not encapsulated, and mild invasive features into surrounding tissue were noted. The mitotic index was 17; 17 mitotic figures were seen in 10 high-power-fields. Atypical mitosis was also seen. Immunohistochemically, tumor cells were positive for vimentin, α-smooth muscle actin, hcaldesmon, desmin (focal), p53, and Ki-67 (labeling index = 34%). No other tumors were identified in the body, and the patient further treated with auxiliary local radiation and chemotherapy (cisplatin and doxorubicin). He is now healthy and free from tumors in the body 15 months after the operation.

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“…LMS of the spermatic cord are uncommon neoplasia of non-testicular origin and generally arises in the sixth or seventh decade. Originally considered to be malignant smooth muscle tumors or leiomyosarcomas arise from embryologic undifferentiated mesenchymal cells of the cremasteric mucle or vas deferens cells [7] . Most paratesticular LMS are 2 to 9 cm in diameter [5] .…”

Section: Discussionmentioning

confidence: 99%

Leiomyosarcoma of Spermatic Cord: Mimicking Inguinal Hernia

Koyuncuer¹

2017

APALM

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Leiomyosarcomas of the spermatic cord are very rare malignant neoplasms.We report one case, a 64-year-old man presented with the painless, swelling, ball shaped mass in the right inguinal canal.Histopathological evaluation including immunohistochemistrystudiesconfirmed a conventional leiomyosarcoma. Currently there has been no evidence local recurrence or distant metastasis for three months of follow-up. Leiomyosarcoma is a extremely malignant tumor; survival is poor. The long-termprognosis of leiomyosarcoma depends principally on stage and histologic grade.There appears to be a lack of concurrence aboutdiagnostic criteria for malignancy opposite the leiomyosarcoma spectrum, but more studies are needed.This article reviews in the literature and the criteria of these tumors is also discussed.

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Leiomyosarcoma of the Spermatic Cord in a Seventy-Five-Year-Old man

Cited by 3 publications

References 9 publications

Spermatic Cord Leiomyosarcoma Rare Case

Spermatic Cord Leiomyosarcoma Rare Case

Leiomyosarcoma of the spermatic cord

Leiomyosarcoma of Spermatic Cord: Mimicking Inguinal Hernia

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