Long-term results of surgical treatment of pigmented villonodular synovitis of the knee

Abstract

PVNS is a disease with a high risk of recurrence. No individual or combined treatment method can offer a definitive solution. Open or arthroscopic radical synovectomy is still considered as the gold standard. If necessary, adjuvant intraarticular or extraarticular radiotherapy can be added to the treatment.

Pigmented villonodular synovitis: a crowdsourcing study of two hundred and seventy two patients

“…Mean follow-up of approximately six years (range 1-31) was longer when compared with the majority of previously published reports [3,19,23,29,31,32]. Together with the relatively high recurrence rates in this study (58-77 % after arthroscopic and 36-64 % after open synovectomy), this may indicate that to date, an underestimate of the true local recurrence rate of PVNS has been published.…”

“…Functional results after surgical treatment for PVNS have been reported (Table 5) [3,[18][19][20][21][22][23][24][25][26][27][28][29][30][31][32], but comparison is difficult, as functional results were not specified for diffuse and localized disease, type of surgery, primary or recurrent disease and different localizations. In this study, there was no difference in functional outcome and QOL between patients who underwent primary arthroscopic or open synovectomy.…”

A severe systemic presentation of pigmented villonodular synovitis in a child with underlying Chediak–Higashi syndrome

“…There are two broad classifications for PVNS presentation: localized (with involvement of a single synovial nodule) and diffuse (destruction of the entire joint synovium) [5]. The clinical manifestations observed are highly variable and may be nonspecific, including joint stiffness, a dull ache and a palpable mass [7,8]. There remains much uncertainty concerning the underlying pathogenesis, with a range of hypotheses proposed such as chronic inflammation and tissue reaction to hemarthrosis or trauma [6].…”

“…PVNS is a locally aggressive disorder of the synovium, tendon sheaths and bursae, usually presenting between 20 and 40 years of age, and it is rare in children [5,7]. There are two broad classifications for PVNS presentation: localized (with involvement of a single synovial nodule) and diffuse (destruction of the entire joint synovium) [5].…”

Pigmented villonodular synovitis

“…Es de etiología desconocida. Tres formas clínicas son conocidas: focal, difusa y tenosinovitis nodular 2,3 . Dada su presentación clínica como monoartritis crónica inespecífica, en ausencia de sintomatología sistémica, el diagnóstico no es fácil y el intervalo hasta llegar al mismo es largo, luego de varios episodios de derrame articular sin etiología definida.…”